Chlorhexidine Gluconate Bathing in Hospital-Based Infection Prevention and Control: A Bibliometric Analysis
Öz
Objective: This study aimed to provide a comprehensive bibliometric analysis of the scientific literature on chlorhexidine gluconate (CHG) bathing in hospital-based infection prevention and control (IPC).
Methods: A bibliometric analysis was conducted using publications retrieved from the Web of Science Core Collection database on March 15, 2026. A structured search strategy combining terms related to chlorhexidine, bathing or decolonization practices, healthcare settings, and infection prevention was applied. Following title and abstract screening according to predefined eligibility criteria, 305 publications were included. Bibliometric indicators and network analyses were performed to examine publication trends, citation performance, collaboration patterns, and research themes.
Results: The findings demonstrated a steady increase in CHG bathing research over time, with a marked growth beginning around 2016. The 305 publications received 11,506 citations, with an average of 37.72 citations per publication and an h-index of 52. The United States was the leading contributor in terms of publication output and international collaboration. Keyword co-occurrence analysis revealed that the literature is primarily focused on intensive care units, healthcare-associated infection prevention, decolonization strategies, and multidrug-resistant organisms. Citation-based analyses indicated that the field is supported by a cohesive and clinically oriented evidence base dominated by influential intervention studies and infection prevention journals.
Anahtar Kelimeler
- Bibliometrics
- Chlorhexidine gluconate
- healthcare-associated infections
- Infection control
- Intensive care units
Destekleyen Kurum
Etik Beyan
Kaynakça
- Armellino, D., Woltmann, J., Parmentier, D., Musa, N., Eichorn, A., Silverman, R., … Farber, B. (2014). Modifying the risk: once-a-day bathing "at risk" patients in the intensive care unit with chlorhexidine gluconate. American Journal of Infection Control, 42(5), 571-573. doi:10.1016/j.ajic.2013.12.026
- Babiker, A., Lutgring, J. D., Fridkin, S., & Hayden, M. K. (2021). Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections. Clinical Infectious Diseases, 72(5), 891-898. doi:10.1093/cid/ciaa1103
- Bleasdale, S. C., Trick, W. E., Gonzalez, I. M., Lyles, R. D., Hayden, M. K., & Weinstein, R. A. (2007). Effectiveness of chlorhexidine bathing to reduce catheter-associated bloodstream infections in medical intensive care unit patients. Archives of Internal Medicine, 167(19), 2073-2079. doi:10.1001/archinte.167.19.2073
- Bode, L. G. M., Kluytmans, J., Wertheim, H. F. L., Bogaers, D., Vandenbroucke-Grauls, C., Roosendaal, R., . . . Vos, M. C. (2010). Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus. The New England Journal of Medicine, 362(1), 9-17. doi:10.1056/NEJMoa0808939
- Centers for Medicare & Medicaid Services. (2026). Hospital-Acquired Condition Reduction Program. Retrieved from https://www.cms.gov/medicare/payment/prospective-payment-systems/acute-inpatient-pps/hospital-acquired-condition-reduction-program-hacrp
- Chen, W. S., Lin, J. Z., Zhang, K., Fang, X. P., Wang, R., Sun, Q. M., . . . Zhuang, G. H. (2025). Bathing with 2% chlorhexidine gluconate versus routine care for preventing surgical site infections after pancreatic surgery: a single-centre randomized controlled trial. Clinical Microbiology and Infection, 31(5), 825-831. doi:10.1016/j.cmi.2025.01.004
- Chlebicki, M. P., Safdar, N., O'Horo, J. C., & Maki, D. G. (2013). Preoperative chlorhexidine shower or bath for prevention of surgical site infection: A meta-analysis. American Journal of Infection Control, 41(2), 167-173. doi:10.1016/j.ajic.2012.02.014
- Climo, M. W., Sepkowitz, K. A., Zuccotti, G., Fraser, V. J., Warren, D. K., Perl, T. M., . . . Wong, E. S. (2009). The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Critical Care Medicine, 37(6), 1858-1865. doi:10.1097/CCM.0b013e31819ffe6d
Ayrıntılar
Birincil Dil
İngilizce
Konular
Hemşirelik Esasları
Bölüm
Araştırma Makalesi
Yazarlar
Yayımlanma Tarihi
14 Ağustos 2026
Gönderilme Tarihi
19 Haziran 2026
Kabul Tarihi
3 Ağustos 2026
Yayımlandığı Sayı
Yıl 2026 Cilt: 28 Sayı: 2