The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.)

Sevda Yuksel; Kalender Arıkan; Çağlan Günal

doi:10.15671/hjbc.1658711

The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.)

Abstract

In this study, the acute toxic effects of cyromazine and hexaflumuron, which are used in vector control, were investigated on the larvae of the common vector mosquito, Aedes aegypti. Mortality rates of Aedes aegypti larvae exposed to six different concentrations of cyromazine and five different concentrations hexaflumuron, two insect growth regulators (IGRs) used for vector control, were determined. Using the obtained data, the concentrations between LC10 and LC99 were calculated by applying the probit analysis method. The knockdown times were also measured based on concentration, and the LT50 was calculated for each concentration. All tests were conducted at Hacettepe University, Pesticide Research and Reference Laboratory. The experiments revealed that the 14-days LC50 for cyromazine was 38.191 g a.i./ha (0.254 ppm) (95% Confidence Interval (CI): 33.296 g a.i./ha or 0.222 ppm and 43.497 g a.i./ha or 0.289 ppm). For hexaflumuron, the 14-days LC50 was 1.247 g a.i./ha (0.00831 ppm) (CI: 0.670 g a.i./ha or 0.00446 ppm and 1.736 g a.i./ha or 0.01157 ppm). For cyromazine, the LT50 values ranged from 5.002 days to 37,59 days, depending on the application doses between 30 g a.i/ha and 100 g a.i/ha, while for hexaflumuron, the LT50 values ranged from 5.677 days to 11.366 days, depending on the application doses between 1 g a.i/ha and 10 g a.i/ha (95% Confidence Interval (CI). Hexaflumuron was found to be more toxic than cyromazine on mosquito larvae. It has been concluded that, for the effective use of both active ingredients in mosquito larval control, cyromazine should be applied at a dose of approximately 65.846 g a.i/ha (0.439 ppm) and hexaflumuron at a dose of 4.707 g a.i/ha (0.0313 ppm).

Keywords

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Details

Primary Language

English

Subjects

Ecology (Other)

Journal Section

Research Article

Authors

Sevda Yuksel ^*
0009-0003-2441-6334
Türkiye

Kalender Arıkan
0000-0002-9862-9629
Türkiye

Çağlan Günal
0000-0002-9072-543X
Türkiye

Publication Date

October 1, 2025

Submission Date

March 15, 2025

Acceptance Date

June 20, 2025

Published in Issue

Year 2025 Volume: 53 Number: 4

DOI

https://doi.org/10.15671/hjbc.1658711

IZ

https://izlik.org/JA73RW58MD

Cite

RIS / Bibtex

APA

Yuksel, S., Arıkan, K., & Günal, Ç. (2025). The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.). Hacettepe Journal of Biology and Chemistry, 53(4), 83-90. https://doi.org/10.15671/hjbc.1658711

AMA

1.Yuksel S, Arıkan K, Günal Ç. The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.). HJBC. 2025;53(4):83-90. doi:10.15671/hjbc.1658711

Chicago

Yuksel, Sevda, Kalender Arıkan, and Çağlan Günal. 2025. “The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes Aegypti L.)”. Hacettepe Journal of Biology and Chemistry 53 (4): 83-90. https://doi.org/10.15671/hjbc.1658711.

EndNote

Yuksel S, Arıkan K, Günal Ç (October 1, 2025) The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.). Hacettepe Journal of Biology and Chemistry 53 4 83–90.

IEEE

[1]S. Yuksel, K. Arıkan, and Ç. Günal, “The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.)”, HJBC, vol. 53, no. 4, pp. 83–90, Oct. 2025, doi: 10.15671/hjbc.1658711.

ISNAD

Yuksel, Sevda - Arıkan, Kalender - Günal, Çağlan. “The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes Aegypti L.)”. Hacettepe Journal of Biology and Chemistry 53/4 (October 1, 2025): 83-90. https://doi.org/10.15671/hjbc.1658711.

JAMA

1.Yuksel S, Arıkan K, Günal Ç. The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.). HJBC. 2025;53:83–90.

MLA

Yuksel, Sevda, et al. “The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes Aegypti L.)”. Hacettepe Journal of Biology and Chemistry, vol. 53, no. 4, Oct. 2025, pp. 83-90, doi:10.15671/hjbc.1658711.

Vancouver

1.Sevda Yuksel, Kalender Arıkan, Çağlan Günal. The Toxic Effect of Cyromazine and Hexaflumuron on Mosquito Larvae (Aedes aegypti L.). HJBC. 2025 Oct. 1;53(4):83-90. doi:10.15671/hjbc.1658711