Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications

Yıl 2020, , 459 - 481, 01.11.2020

Brabu Balusamy Anitha Senthamizhan Tamer Uyar

https://doi.org/10.15671/hjbc.789186

Cited By: 4

Öz

Electrospinning has received tremendous attention in the fabrication of nanofibrous scaffolds over recent years and employed in different biomedical applications because of their biomimetic nature. Especially, the electrospun nanofibers exhibit several beneficial features including natural extracellular matrix (ECM), interconnected pores, large surface area, ease of functionalization and mechanical performance that holds huge importance in influencing the cell adhesion, differentiation and proliferation behaviour. To date, acknowledging the wide range of beneficial features, the electrospun nanofibers have been used in wound dressing and tissue engineering applications. This review summarizes various efforts have been made in these areas with several representative examples indicating use of various materials and approaches. Further the concerns for future direction regard to clinical phase transfer has been discussed.

Anahtar Kelimeler

Electrospinning, Nanofibers, Wound Dressing, Tissue Engineering

Kaynakça

• 1. T. Lin, J. Fang, Fundamentals of electrospinning & electrospun nanofibers, DEStech Publications, Inc, Pennsylvania, USA, 2017.
• 2. Z. Li, C. Wang, One-dimensional nanostructures: Electrospinning technique and unique nanofibers, Springer-Verlag, Berlin Heidelberg, Germany, 2013.
• 3. B. Ding, X. Wang, J. Yu, Electrospinning: Nanofabrication and applications, William Andrew, Elsevier, Amsterdam, Netherland, 2019.
• 4. G.R. Mitchell, Electrospinning: Principles, practice and possibilities, The Royal Society of Chemistry, Cambridge, UK, 2015.
• 5. J.H. Wendorff, S. Agarwal, A. Greiner, Electrospinning: Materials, processing, and applications, Wiley, Weinheim, Germany, 2012.
• 6. J. Xue, T. Wu, Y. Dai, Y. Xia, Electrospinning and electrospun nanofibers: Methods, materials, and applications, Chem. Rev., 119 (2019) 5298–5415.
• 7. S. Mohammadzadehmoghadam, Y. Dong, S. Barbhuiya, L. Guo, D. Liu, R. Umer, X. Qi, Y, Tang, Electrospinning: Current status and future trends, In: S. Fakirov (eds), Nano-size polymers, Springer, Cham, Switzerland, 2016, pp. 89-154.
• 8. F. Topuz, T. Uyar, Electrospinning of cyclodextrin functional nanofibers for drug delivery applications, Pharmaceutics, 11 (2019) 6.
• 9. A.F. Ismail, N. Hilal, J. Jaafar, C. Wright, Nanofiber membranes for medical, environmental, and energy applications, CRC Press, Boca Raton, FL, USA 2019.
• 10. B. Ding, J. Yu, Electrospun nanofibers for energy and environmental applications, Springer, Berlin/Heidelberg, Germany, 2014.
• 11. G. Sun, L. Sun, H. Xie, J. Liu, Electrospinning of nanofibers for energy applications, Nanomaterials, 6 (2016), 129.
• 12. H. Liu, C.R. Gough, Q. Deng, Z. Gu, F. Wang, X. Hu, Recent advances in electrospun sustainable composites for biomedical, environmental, energy, and packaging applications, Int. J. Mol. Sci., 21 (2020) 4019.
• 13. Z. Tong, L. Huang, W. Lei, H. Zhang, S. Zhang, Carbon-containing electrospun nanofibers for lithium–sulfur battery: Current status and future directions, J. Energy Chem., 54 (2021), 254–273.
• 14. M. Focarete, C. Gualandi, S. Ramakrishna, Filtering media by electrospinning, Springer, Cham, Switzerland, 2018.
• 15. B. Balusamy, A. Senthamizhan, T. Uyar, Functionalized electrospun nanofibers as a versatile platform for colorimetric detection of heavy metal ions in water: A review, Materials, 13 (2020), 2421.
• 16. A. Senthamizhan, A. Celebioglu, B. Balusamy, T. Uyar, Immobilization of gold nanoclusters inside porous electrospun fibers for selective detection of Cu(II): A strategic approach to shielding pristine performance, Sci. Rep., 5 (2015), 15608.
• 17. A. Senthamizhan, B. Balusamy, Z. Aytac, T. Uyar, Grain boundary engineering in electrospun ZnO nanostructures as promising photocatalysts, CrystEngComm., 18 (2016), 6341–6351.
• 18. B. Balusamy, A. Senthamizhan, T. Uyar, Surface functionalized electrospun nanofibers for removal of toxic pollutants in water, In: A.F. Ismail, N. Hilal, J. Jaafar, C. Wright (Eds.), Nanofiber Membranes for Medical, Environmental, and Energy Applications, CRC Press, Boca Raton, FL, USA, 2019, pp. 189–213.
• 19. A. Senthamizhan, B. Balusamy, T. Uyar, Electrospun filters for organic pollutants removal, In: M. Focarete, C. Gualandi, S. Ramakrishna, (Eds.), Filtering Media by Electrospinning, Springer, Cham, Switzerland, 2018, pp. 115–150.
• 20. A. Senthamizhan, A. Celebioglu, T. Uyar, T, Real-time selective visual monitoring of Hg2+ detection at ppt level: An approach to lighting electrospun nanofibers using gold nanoclusters, Sci. Rep., 5 (2015), 10403.
• 21. A. Senthamizhan, B. Balusamy, A. Celebioglu, T. Uyar, “Nanotraps” in porous electrospun fibers for effective removal of lead(II) in water, J. Mater. Chem. A, 4 (2016), 2484–2493.
• 22. B. Balusamy, O.F. Sarioglu, A. Senthamizhan, T. Uyar, Rational design and development of electrospun nanofibrous biohybrid composites, ACS Appl. Bio. Mater., 2 (2019), 3128–3143.
• 23. A. Senthamizhan, T. Uyar, Electrospun fluorescent nanofibers for explosive detection, in: A. Macagnano, E. Zampetti, E. Kny (Eds.), Electrospinning for High Performance Sensors, Springer, Cham, Switzerland, 2015, pp. 179–204.
• 24. S. Anitha, B. Brabu, K.P. Rajesh, T.S. Natarajan, Fabrication of UV sensor based on electrospun composite fibers, Mater. Lett. 92 (2013), 417–420.
• 25. X. Wang, J. Yu, G. Sun, B. Ding, Electrospun nanofibrous materials: a versatile medium for effective oil/water separation, Mater. Today, 19 (2016), 403–414.
• 26. A. Senthamizhan, A. Celebioglu, T. Uyar, Flexible and highly stable electrospun nanofibrous membrane incorporating gold nanoclusters as an efficient probe for visual colorimetric detection of Hg(II), J. Mater. Chem. A 2 (2014), 12717–12723.
• 27. B. Balusamy, A. Senthamizhan, T. Uyar, Functionalized electrospun nanofibers as colorimetric sensory probe for mercury detection: A review, Sensors 19 (2019), 4763.
• 28. D. Lv, M. Zhu, Z. Jiang, S. Jiang, Q. Zhang, R. Xiong, C. Huang, Green electrospun nanofibers and their application in air filtration, Macromol. Mater. Eng., 303 (2018) 1800336.
• 29. B. Balusamy, A. Celebioglu, A. Senthamizhan, T. Uyar, Progress in the design and development of “fast-dissolving” electrospun nanofibers based drug delivery systems - A systematic review, J. Control. Release, 326 (2020) 482–509.
• 30. A.B. Tekinay, B. Balusamy, A. Senthamizhan, T. Uyar, Neuroregenerative Nanotherapeutics, In: A.B. Tekinay (Ed.), Nanomaterials for Regenerative Medicine. Stem Cell Biology and Regenerative Medicine, Springer, Humana, Cham, Switzerland, 2019, pp. 143–181.
• 31. T. Uyar, E. Kny, Electrospun Materials for Tissue Engineering and Biomedical Applications: Research, Design and Commercialization, first ed., Woodhead Publishing Series in Biomaterials, Elsevier, Cambridge, 2017.
• 32. A. Senthamizhan, B. Balusamy, T. Uyar, Recent progress on designing electrospun nanofibers for colorimetric biosensing applications, Curr. Opin. Biomed. Eng., 13 (2020), 1–8.