Preparation of Molecularly Imprinted Optical Sensors for The Real Time Detection of Phenol

Abstract

Son yıllarda, canlılar ve halk sağlığı için önemli bir tehdit oluşturan fenol ve bileşiklerinin tespit edilmesi önem kazanmaktadır. Bu çalışmada, fenolün tespiti için moleküler baskılama yöntemi temel alınarak yüzey plazmon rezonans (SPR) sensörler tasarlanmıştır. Fenol moleküllerine ait boşluklara sahip polimerik film hazırlanarak UV polimerizasyonu ile SPR sensör yüzeyinden oluşturulmuştur. 0.15 ila 10 nM arasındaki tayin aralığında en düşük saptama sınırı 0.011 nM’dir. Ayrıca, biz katekolün yarışmacı ajan olarak seçicilik deneylerini gerçekleştirdik. Genel olarak, moleküler baskılama yaklaşımı ile hazırlanan fenol baskılanmış SPR sensörünün fenol için oldukça hassas ve seçici olduğu bulunmuştur. Fenol baskılı SPR sensörleri, yüksek seçicilikleri, tekrarlayan kullanımları ve hızlı yanıtları özelliği ile mevcut fenol belirleme yöntemlerine yeni bir yöntem olarak kullanılmak düşünülmektedir.

Keywords

• Phenol
• molecular imprinting
• sensor
• surface plasmon resonance

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