The Effect of Interval Training Program on Nuclear Factor Erythroid-Derived 2-like 2 (NFE2L2/Nrf2) Gene Expression in Women

Yıl 2019, Cilt: 47 Sayı: 4, 410 - 414, 01.12.2019

Neşe Akpınar

https://doi.org/10.15671/hjbc.546962

Cited By: 1

Öz

Purpose in this
work, to investigate whether interval training
program has an effect on Nuclear factor
erythroid-derived 2-like 2 (NFE2L2/Nrf2)
gene expression in women.The research
was made on 12 women. Participants
were given a medium-term interval training program for 8 weeks, 3 days a week. The 
blood samples of the participants were collected before and after the 8
weeks of training. RNA isolation was performed using TRIzol Reagent from
peripheral blood mononuclear cells. NFE2L2 gene expression was
determined by Biomark Real-Time PCR (RT-PCR). The participants  was a significant increase in heart rate and
maximal oxygen use capacity (VO₂ max ) after the exercise (p
<0.001). There was a significant decrease in the body weight and body mass
index of women after the exercise (p <0.001). There was a decrease in NFE2L2
gene expressions after 8 weeks of the training program (p <0.05,). It shows that
interval exercise reduces NFE2L2 gene expression in women. 

Anahtar Kelimeler

Exercise, gene expression, NFE2L2 gene, interval training

Kaynakça

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