In this study, the antibacterial and cytotoxic activities of some amino acid methyl esters (L-methionine, L-phenylalanine, L-histidine, L-lysine, L-tryptophan, and L-tyrosine) were investigated. The effect of amino acid methyl ester compounds on antibacterial performance was determinated against Gram-negative and Gram-positive bacteria. The effect of amino acid esters on cell viability was investigated against cancerous and non-cancerous cell lines using the MTS assay. The results showed the substances had low antimicrobial effect on both Gram-negative and Gram-positive bacteria. In addition, it was found that the studied substances did not have a toxic effect on cell growth in non-cancerous cells. For this reason, it is thought that the results obtained will contribute to research on new synthesizable compounds based on amino acid esters and studies on drug development.
Amino Acid Esters Antibacterial Activity Antiproliferative Activity Cytotoxicity
Birincil Dil | İngilizce |
---|---|
Konular | Mühendislik |
Bölüm | Articles |
Yazarlar | |
Yayımlanma Tarihi | 1 Nisan 2023 |
Kabul Tarihi | 1 Kasım 2022 |
Yayımlandığı Sayı | Yıl 2023 Cilt: 51 Sayı: 2 |
HACETTEPE JOURNAL OF BIOLOGY AND CHEMİSTRY
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