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Yıl 2021, Cilt: 5 Sayı: 1, 39 - 56, 30.04.2021
https://doi.org/10.30704/http-www-jivs-net.892668

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Current invasive and non-invasive biomarkers in canine mammary tumors

Yıl 2021, Cilt: 5 Sayı: 1, 39 - 56, 30.04.2021
https://doi.org/10.30704/http-www-jivs-net.892668

Öz

In bitches, the incidence of mammary tumors is determined at %50 of all neoplasms. Most of the cases are malignant and tend to metastasize. Because of this, early diagnosis has an important value. Due to the molecular and clinical similarities of canine mammary tumors to human breast cancers, human breast cancer markers are also detectable in cases of canine mammary tumors. Generally, biomarkers provide information about criteria such as clinical diagnosis, early diagnosis, prognosis, and determination of the treatment protocol. When choosing the appropriate biomarker, it should be taken into account that it is easy to apply, has a positive correlation with tumor specificity and malignancy, and whether gives precise information about prognosis. Due to the heterogeneous nature of canine mammary tumors, an ideal biomarker has not determined yet. However, new studies have revealed the existence of many biomarkers. In this review it is given to qualified and current biomarkers can be used in dogs, including invasive and non-invasive mammary tumor biomarkers.

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  • 155. Tavares, W. L., Lavalle, G. E., Figueiredo, M. S., Souza, A. G., Bertagnolli, A. C., Viana, F. A. B., … & Cassali, G. D. (2010). Evaluation of adverse effects in tamoxifen exposed healthy female dogs. Acta Veterinaria Scandinavica, 52 (1), 67.
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  • 170. Zha, C., Jiang, X. H., & Peng, S. F. (2015). iTRAQ-based quantitative proteomic analysis on S100 calcium binding protein A2 in metastasis of laryngeal cancer. Public Library of Science One, 10 (4), e0122322.
  • 171. Zhang, S., Wang, Z., Liu, W., Lei, R., Shan, J., Li, L., & Wang, X. (2017). Distinct prognostic values of S100 mRNA expression in breast cancer. Scientific Reports, 7 (1), 1-11.
  • 172. Zhang, Y., Sun, H., Wu, H., Tan, Q., & Xiang, K. (2015). Interleukin 35 is an independent prognostic factor and a therapeutic target for nasopharyngeal carcinoma. Contemporary Oncology, 19 (2), 120.
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  • 174. Zuccari, D. A., Santana, A. E., Cury, P. M., & Cordeiro, J. A. (2004). Immunocytochemical study of Ki‐67 as a prognostic marker in canine mammary neoplasia. Veterinary Clinical Pathology, 33 (1), 23-28.
Toplam 172 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Veteriner Cerrahi
Bölüm Derleme Makaleler
Yazarlar

Aslihan Baykal 0000-0002-2107-1874

Özge Turna 0000-0002-7638-0519

Yayımlanma Tarihi 30 Nisan 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 5 Sayı: 1

Kaynak Göster

APA Baykal, A., & Turna, Ö. (2021). Current invasive and non-invasive biomarkers in canine mammary tumors. Journal of Istanbul Veterinary Sciences, 5(1), 39-56. https://doi.org/10.30704/http-www-jivs-net.892668

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