In-vivo evaluation of an innovative feed additive formulation of Pinus Brutia Ten. resin containing turpentine and colophony and the effects on milk production performance and somatic cell counts of holstein dairy cows

Yıl 2023, Cilt: 7 Sayı: 1, 1 - 7, 30.04.2023

Ozan Tekdemir Esher Özçelik İsmail Abaş Yıldız Özsoy

https://doi.org/10.30704/http-www-jivs-net.1177127

Öz

The aim of this study was to investigate a feed additive which is expected to be preventative, consist of new active ingredients for mastitis disease which is frequently seen in dairy cattle. For these purposes colophony which has antibacterial and turpentine which has antibacterial, antifungal effects have a potential that is researched in vitro previously. These herbal ingredients were suggested to use for prevention of mastitis in dairy cattle. Powdered herbal material have colophony and turpentine %96.5 0.3 and %3.5 0.3, respectively. Animal assay was studied with two group (experimental, control) which have 15 dairy cattle each and at the end of the study milk parameters, somatic cell count (SCC), average milk productions discussed. Although it was not statistically significant the amount of milk and the amount of fat in the milk increased and SCC decreased more in the experimental group compared to the controlled group within two weeks.

Anahtar Kelimeler

Bovine mastitis, colophony, turpentine, feed additive

Destekleyen Kurum

The Research Fund of Istanbul University

Proje Numarası

TDK-2018-26395

Kaynakça

• Referans 1 Adkins, P. R. F., Middleton, J. R. (2018). Methods for Diagnosing Mastitis, The Veterinary Clinics of North America. Food Animal Practice, 34(3) 479–491.
• Referans 2 Bradley, A. J. (2002). Bovine mastitis: an evolving disease. Veterinary Journal, 164(2), 116–128.
• Referans 3 Dığrak, M., İlçim, A., Hakkı Alma, M. (1999). Antimicrobial activities of several parts of Pinus brutia, Juniperus oxycedrus, Abies cilicia, Cedrus libani and Pinus nigra. Phytherapy Research, 13(7), 584–587.
• Referans 4 Dohoo, I. R., Meek, A. H. (1982). Somatic cell counts in bovine milk. Canadian Veterinary Journal, 23(4), 119–125.
• Referans 5 Golden, R. (2006, January 5). Rosin-Review and Summary of Human Health and Ecological Toxicity Data. Retrieved from https://www.pinechemicals.org/page/ID600TOXROSINRE/ROSIN---REVIEW-AND-SUMMARY-OF-HUMAN-HEALTH-AND-ECOLOGICAL-TOXICITY-DAT.htm.
• Referans 6 Gigante, B., Santos, C., Silva, A. M., Curto, M. J. M., Nascimento, M. S. J., Pinto, E., Pedro, M., Cerqueira, F., Pinto, M. M., Duarte, M. P., Laires, A., Rueff, J., Goncalves ̧ J., Pegado M. I., Valdeira M. L. (2003). Catechols from abietic acid: synthesis and evaluation as bioactive compounds. Bioorganic  Medicinal Chemistry, 11(8), 1631–1638.
• Referans 7 Jan, H. (Ed.). (2009). Method of analysis. In European Pharmacopoeia, vol. 7.
• Referans 8 Kettunen, H., Vuorenmaa, J., Rinttilä, T., Grönberg, H., Valkonen, E.,  Apajalahti, J. (2015). Natural resin acid –enriched composition as a modulator of :intestinal microbiota and performance enhancer in broiler chicken. Journal of Applied Animal Nutrition, 3, e2.
• Referans 9 Koç, A. (2008). A study of somatic cell counts in the milk of Holstein-Friesian cows managed in mediterranean climatic conditions. Turkish Journal of Veterinary Science., 32(1), 13-18.
• Referans 10 Mercier, B., Prost, J.,  Prost, M. (2009). The essential oil of turpentine and its major volatile fraction (α- and β-pinenes): A review. International Journal of Occupational Medicine and Environmental Health. 22(4), 331-342.
• Referans 11 Moran, J. (2005). Tropical Dairy Farming: Feeding Management for Small Holder Dairy Farmers in the Humid Tropics. Collingwood, Australia: Landlinks Press.
• Referans 12 Moreira, M. A. S., Júnior, A. S., Lima, M. C.,  Costa, S. L. (2019). Infectious Diseases in Dairy Cattle, In L. A. Nero,  A. F. De Carvalho (Eds). Raw Milk, (pp. 235–258). London,UK, San Diego, California, USA: Academic Press, Elsevier.
• Referans 13 Roy, K., Lyhs, U., Vuorenmaa, J.,  Pedersen, K. (2018). In vitro inhibition studies of natural resin acids to Clostridium perfringens, Staphylococcus aureus and Escherichia coli O149. Jornal of Applied Animal Nutrition, 6, e2.
• Referans 14 Ruegg, P. L. (2017). A 100-Year Review: Mastitis detection, management, and prevention. Journal of Dairy Science, 100(12), 10381–10397.
• Referans 15 Saeidnia, S. (2014). Turpentine, In P. Wexler (Ed). Encyclopedia of Toxicology (pp. 860–865). Oxford, UK: Academic Press, Elsevier.
• Referans 16 Savluchinske Feio, S., Gigante, B., Roseiro, J. C,  Marcelo-Curto, M. J. (1999). Antimicrobial activity of diterpene resin acid derivatives. Journal of Microbiological Methods, 35(3), 201-206.
• Referans 17 Seegers, H., Fourichon, C.,  Beaudeau, F. (2003). Production effects related to mastitis and mastitis economics in dairy cattle herds. Veterinary Research., 34(5), 475–491.
• Referans 18 Sharma, N., Singh, N. K., & Bhadwal, M. S. (2011). Relationship of Somatic Cell Count and Mastitis: An Overview. Asian-Australasian Journal of. Animal Science., 24(3), 429–438.
• Referans 19 Sierra-Alvarez, R.,  Lettinga, G. (1990). The methanogenic toxicity of wood resin constituents. Biological Wastes, 33(3), 211–226.
• Referans 20 Tanaka, R., Tokuda, H.,  Ezaki, Y. (2008). Cancer chemopreventive activity of ‘rosin’ constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test. Phytomedicine, 15(11), 985–992.
• Referans 21 Ulukanli, Z., Karabörklü, S., Bozok, F., Ateş, B., Erdoğan, S., Cenet, M.,  Karaaslan M.G. (2014). Chemical composition, antimicrobial, insecticidal, phytotoxic and antioxidant activities of Mediterranean Pinus brutia and Pinus pinea resin essential oils. Chinese Journal of Naturel Medicines, 12(12), 901-910.
• Referans 22 Vulava, V. M. (2005). Turpentine, In P. Wexler (Ed). Encyclopedia of Toxicology (pp. 394–397). New York, USA: Academic Press, Elsevier.