Evaluation of the efficiency of TENS therapy to the regeneration in N. ischiadicus injured rats

Yıl 2024, Cilt: 8 Sayı: 3, 335 - 342, 31.12.2024

Ebru Eravcı Yalın , Yalçın Devecioğlu

Öz

Transcutaneous electrical nerve stimulation (TENS) is one of the electrotherapy methods, used for physical therapy, to relieve neuropathic pain in the nervous system lesion. However, the effect on peripheral nerve regeneration has been unknown. This work aims to examine peripheral nervous system diseases in which fullness is preserved, the efficiency of TENS to hasten healing, and the suitability of magnetic resonance imaging to diagnose peripheral nervous system diseases. Also, electrophysiologic findings of functional nerve recuperation will be considered after comparing with histopathologic and magnetic resonance imaging. 72 Sprague Dawley rats were randomly assigned to four groups. Group 1; normal without crush lesion, Group 2; control group with crush lesion, Group 3; stimulated group on lesion area, Group 4; stimulated group on gastrocnemius muscle. The animals were sacrificed post-operatively 21. day and 45. day after the electrophysiological, assessment and walking trace analysis, magnetic resonance imaging and nerve samples were obtained for histologic analysis. According to this study, low-frequency TENS leads to delayed regeneration after a crush lesion of the sciatic nerve in rats.

Anahtar Kelimeler

TENS, rat, nerve regeneration, EMG, electrophysiology

Etik Beyan

I declare that this thesis is my own work, and that I have not engaged in any unethical behavior throughout all stages of the thesis, from its planning to its writing. I obtained all the information in this thesis within academic and ethical guidelines, and I have cited all the information and interpretations that were not derived from my own research. These sources are also included in the reference list. Furthermore, I declare that no patent or copyright laws have been violated during the preparation and writing of this thesis."

Proje Numarası

10347

Kaynakça

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