Paliperidon palmitat enjeksiyonu sonrasi gelişen akatizinin mirtazapinle başarili tedavisi: Bir olgu sunumu

Yıl 2018, Cilt: 15 Sayı: 3, 259 - 261, 12.12.2018

Hamza Ayaydın Şermin Bilgen Ulgar

Öz

Paliperidon palmitat uzun etkili enjekte edilebilir bir preparattır ve şizofreninin akut ve idame tedavisinde endikedir. Akatizi, iç huzursuzluk ve hareket etmeye devam etme gereksinimi ile karakterize ekstrapiramidal bir semptomdur. Antipsikotikle indüklenen akatizi tedavisinde β-blokerler, benzodiazepinler ve antikolinerjikler kullanılmasına rağmen, mirtazapinin de etkili olduğu gösterilmiştir. Ancak, literatür taramamızda, uzun etkili antipsikotiklerin kullanımıyla ilişkili akatizi tedavisinde mirtazapin kullanımıyla ilgili bir olguya rastlanmamıştır. Bu olgu rutin akatizi tedavisiyle fayda görmeyip, sadece mirtazapinden yarar görmüştür.

Anahtar Kelimeler

Antipsikotik, Şizofreni, Paliperidon palmitat, Akatizi, Mirtazapin

Successful treatment of paliperidone palmitate induced akathisia with mirtazapine: A case report

Öz

Paliperidone palmitate is a long-acting injectable preparation and is indicated in acute and maintenance treatment of schizophrenia. Akathisia is an extrapyramidal symptom characterized by inner restlessness and the need to keep moving. Although β-blockers, benzodiazepines and anticholinergics have been used in the treatment of antipsychotic-induced akathisia, mirtazapine is also effective in the treatment of antipsychotic-induced akathisia. However, our search of literature did not reveal any cases of use mirtazapine in the treatment of akathisia associated with the use of long-acting antipsychotics. In this case, we used each treatment line to be used in the treatment of akathisia; however, the patient could be stabilized only by mirtazapine.

Anahtar Kelimeler

Schizophrenia, Paliperidone palmitate, Akathisia, Mirtazapine, Antipsychotic

Kaynakça

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