Uyku, melatonin ve kanser ilişkisi

Yıl 2018, Cilt: 3 Sayı: 1-2 , 38 - 41 , 04.04.2019

Ali Çimen Yasemin Akbaş Oytun Erbaş

https://izlik.org/JA43GF88UN

Öz

Pineal bezinden salgılanan melatoninin sentezi primer olarak karanlığa bağlıdır. Uyku sırasında yapay ışığa maruz kalmak, pineal fonksiyonları akut olarak baskıladığından melatoninin salgılanmasını bozar. Bu bozukluk birçok patolojik duruma ek olarak hormon bağımlı kanserlerden olan meme ve prostat kanseri riskini de artırabilir. Melatonin, antioksidan ve hücre siklusunu yavaşlatıcı özellikleri sayesinde kemoterapi ajanının etkinliğini artırır. Bu nedenle melatonin, hem tek başına hem de diğer tedavilerle birlikte meme ve prostat kanseri için güvenli ve etkili bir tedavi olarak kullanılabilir.

Anahtar Kelimeler

Kanser , sirkadiyen ritim , melatonin , pineal bez , uykusuzluk

Kaynakça

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