Mekanik Ventilasyon Desteğindeki Hastalarda Vip Önlemek İçin Kullanılan Ağız Bakım Solüsyonlarının Etkinliği: Sistematik İnceleme ve Meta-Analiz

Öz

Bu araştırma mekanik ventilasyon desteğindeki hastalarda farklı ağız bakım solüsyonlarının ventilatörle ilişkili pnömoni üzerine etkisini belirlemek amacıyla yapılmıştır. Mekanik ventilasyon desteğindeki hastalarda ağız bakımı solüsyonlarının VİP'i önlemedeki etkinliğini değerlendirmek için PubMed, EBSCO, Embase, Web of Science, Clinical Trials gibi veri tabanlarından ve Türkiye Ulusal elektronik veri tabanlarından randomize kontrollü çalışmalar tarandı. Genel olarak, 2028 taramadan elde edilen toplam 10 randomize kontrollü deneysel çalışma analize dahil edildi. Çalışmaların toplam örneklem büyüklüğü 777'dir (müdahale grubu: 417; kontrol grubu: 360). Bu meta-analizde kapsamlı ağız bakımı VİP enfeksiyonu olasılığını azaltmada etkiliydi ancak hangi çözümün daha etkili olduğu konusunda net bir sonuca varılamadı. Bu sonuçlara dayanarak, mekanik ventilasyondaki hastalarda VİP'i önlemede hangi ağız bakım çözümlerinin daha etkili olduğu konusunda bir sonuca varmak için daha güçlü kanıtlara ihtiyaç vardır.

Anahtar Kelimeler

• yoğun bakım ünitesi
• meta-analiz
• ağız bakımı
• ağız bakım solüsyonları
• ventilatör ilişkili pnömoni

Effectiveness of oral care solutions to prevent VAP in patients on mechanical ventilation: Systematic review and meta-analysis

Öz

This study was conducted to determine the effect of different oral care solutions on ventilator-associated pneumonia in patients under mechanical ventilation. To evaluate the effectiveness of oral care solutions in preventing VAP in patients under mechanical ventilation, randomized controlled studies were searched from databases such as PubMed, EBSCO, Embase, Web of Science, Clinical Trials and Turkey’s National electronic databases. Overall, a total of 10 randomized controlled experimental studies from 2028 scans were included in the analysis. The total sample size of the studies was 777 (intervention group: 417; control group: 360). In this meta-analysis, comprehensive oral care was effective in reducing the likelihood of VAP infection, but did not provide a clear conclusion as to which solution was more effective. Based on these results, stronger evidence is needed to reach to a conclusion about which of the oral care solutions are more effective in preventing VAP in patients on mechanical ventilation.

Anahtar Kelimeler

• intensive care unit
• meta-analysis
• oral care
• oral care solution
• ventilator-associated pneumonia

Destekleyen Kurum

This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.

Etik Beyan

Not applicable as this is systematic review, this paper was provided based on researching in global databases.

Kaynakça

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