Kanser Tanı ve Tedavisinde Manyetik Nanopartikülker

Öz

Son zamanlarda, geleneksel kanser tanı ve tedavisinin ortaya koyduğu yan etkileri azaltmak ya da ortadan kaldırmak için etkili yaklaşımlar bulmaya yönelik önemli çalışmalar yapılmıştır. Bu nedenle, manyetik nanopartiküller (MNP) benzersiz fiziksel özellikleri, manyetik duyarlılık, biyouyumluluk ve kararlılıklarından dolayı çok ilgi çekmiştir. Özellikle in vivo biyomedikal uygulamalarda kullanılacak manyetik nanomalzemeler; boyut, morfoloji, yüzey kimyası, biyobozunurluk ve isteğe bağlı spesifik hedefleme gibi özel kriterleri karşılamaya ihtiyaç duyar. Biyomedikal uygulamalar için, nanopartiküller en çok hipertermi, ilaç salımı ve Manyetik Rezonans Görüntüleme (MRG) için kontrast ajanları olarak kullanılmaktadır.

Anahtar Kelimeler

• Kanser,Manyetik Nanopartikül,Manyetik Rezonans Görüntüleme,Hipertermi,İlaç Salımı

Magnetic Nanoparticles In The Diagnosis And Treatment Of Cancer

Öz

Recently, significant studies have been carried out to find effective approaches to reduce or eliminate the side effects of traditional cancer diagnosis and treatment. In this context, magnetic nanoparticles (MNP) have attracted much attention due to their unique physical properties, magnetic susceptibility, biocompatibility and stability. Magnetic nanoparticles particularly to be used for in vivo biomedical applications need to fulfill special criteria such as size, morphology, surface chemistry, biodegradation, and specific targeting in biomedical applications, the nanoparticles are mostly used as contrast agents for hyperthermia, drug release and Magnetic Resonance Imaging (MRI).

Anahtar Kelimeler

• Cancer,Magnetic Nanoparticle,Magnetic Resonance Imaging,Hyperthermia,Drug Release

Kaynakça

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