A Bioactive dihydroflavonol-3-O-α-L-rhamnoside from Bracystelma togoense Schtlr
Öz
A compound isolated from the MeOH extract Brachystelma togoense showed activity against some pathogenic microorganisms which included Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella typhi, and Candida albicans ˂ 3 mg/ml. The compound had minimum inhibitory concentration ranging from 0.18 to 0.75mg/ml and minimum bactericidal concentration ranging from 0.75 to 1.50 mg/ml. The compound, dihydroflavonol-3-O-α-L-rhamnoside was identified using 1D and 2D NMR spectroscopic methods and mass spectrometry and by comparison with literature data. The compound is reported for the first time from Brachystelma togoense.
Anahtar Kelimeler
Destekleyen Kurum
Proje Numarası
Teşekkür
Kaynakça
- Bello, I.A., Ndukwe, G.I., Audu, O.T., Habila, J.D., 2011a. A bioactive flavonoid from Pavetta crassipes K. Schum. Organic and Medicinal Chemistry Letters 1, 14.
- Bello, I.A., Ndukwe, G.I., Audu, O.T., Habila, J.D., 2011b. A bioactive flavonoid from Pavetta crassipes K . Schum. Organic and Medicinal Chemistry Letters 1:14, 10–15.
- Britto, S.J., Bruyns, P. V, 2016. Three new species of Brachystelma from Tamil Nadu, India. Haseltonia 48–54.
- Bruyns, P. V, 2009. Three New Species of Brachystelma (Apocynaceae, Asclepiadoideae, Ceropegieae) from South Tropical and Southern Africa. SPIE.
- CLSI. Performing Standards for Antimicrobial Susceptibility Testing, Clinical and Laboratory Standards Institute, 2017:32, n.d. PL, 27 th. ed.
- Cushnie, T.P.T., Lamb, A.J., 2005. Antimicrobial activity of flavonoids. International Journal of Antimicrobial Agents 26, 343–356.
- De Britto, J., Soosai Manickam, V., Gopalakrishnan, S., Ushioda, T., Tanaka, N., 1995. Chemical and chemotaxonomical studies of ferns. Determination of aglycone chirality in dihydroflavonol 3-O-.ALPHA.-L-rhamnosides by 1H-NMR spectroscopy.
- Ekalu, A., Ayo, R.G., Habila, J.D., Hamisu, I., 2019. Phaeophytin and Triterpenoids from Brachystelma togoense Schltr , a Nigerian Medicinal Herb. Asian Journal of Chemical Sciences 6, 1–5.
Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
Araştırma Makalesi
Yazarlar
Abiche Ekalu
*
0000-0002-6471-5019
Nigeria
Yayımlanma Tarihi
30 Haziran 2019
Gönderilme Tarihi
25 Mayıs 2019
Kabul Tarihi
25 Haziran 2019
Yayımlandığı Sayı
Yıl 2019 Cilt: 2 Sayı: 1