Kanser Tanı ve Tedavisinde Manyetik Nanopartikülker

Yıl 2018, Cilt: 1 Sayı: 1, 23 - 30, 01.06.2018

Ali Erdoğan

Öz

Son zamanlarda, geleneksel kanser tanı
ve tedavisinin ortaya koyduğu yan etkileri azaltmak ya da ortadan kaldırmak için
etkili yaklaşımlar bulmaya yönelik önemli çalışmalar yapılmıştır. Bu nedenle, manyetik
nanopartiküller (MNP) benzersiz fiziksel özellikleri, manyetik duyarlılık, biyouyumluluk
ve kararlılıklarından dolayı çok ilgi çekmiştir. Özellikle in vivo biyomedikal uygulamalarda
kullanılacak manyetik nanomalzemeler; boyut, morfoloji, yüzey kimyası, biyobozunurluk
ve isteğe bağlı spesifik hedefleme gibi özel kriterleri karşılamaya ihtiyaç duyar.
Biyomedikal uygulamalar için, nanopartiküller en çok hipertermi, ilaç salımı ve
Manyetik Rezonans Görüntüleme (MRG) için kontrast ajanları olarak kullanılmaktadır.

Anahtar Kelimeler

Kanser, Manyetik Nanopartikül, Manyetik Rezonans Görüntüleme, Hipertermi, İlaç Salımı

Magnetic Nanoparticles In The Diagnosis And Treatment Of Cancer

Öz

Recently, significant studies have
been carried out to find effective approaches to reduce or eliminate the side
effects of traditional cancer diagnosis and treatment. In this context,
magnetic nanoparticles (MNP) have attracted much attention due to their unique
physical properties, magnetic susceptibility, biocompatibility and stability.
Magnetic nanoparticles particularly to be used for in vivo biomedical applications
need to fulfill special criteria such as size, morphology, surface chemistry, biodegradation,
and specific targeting in biomedical applications, the nanoparticles are mostly
used as contrast agents for hyperthermia, drug release and Magnetic Resonance
Imaging (MRI).

Anahtar Kelimeler

Cancer, Magnetic Nanoparticle, Magnetic Resonance Imaging, Hyperthermia, Drug Release

Kaynakça

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