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DIAGNOSTIC VALUE OF FIBEROPTIC BRONCHOSCOPY IN PULMONARY TUBERCULOSIS CASES WHO COULD NOT EXPECTORATE AND SMEAR NEGATIVE

Yıl 2002, Cilt: 16 Sayı: 2, 1 - 14, 01.10.2002

Öz

In this study, the diagnostic value of fiberoptic bronchoscopy (FOB) and related applications in pulmonary tuberculosis cases who could not expectorate and smear negative was investigated. One hundred and eleven cases who were diagnosed as active pulmonary tuberculosis and FOB applied for the diagnosis between 1995-99 years involved in the study. Thirtytwo of cases could not expectorate and 79 were smear negative. 7%(2/32) of gastric juice cultures, 33%(26/79) of sputum cultures totally 25%(28/111) of materials which were taken before bronchoscopy were positive. FOB provided early diagnosis in 40(36%) cases. FOB was diagnostic in 64(56%) cases. Smear and culture positivity in FOB related applications was determined as; 16-31% in bronchial lavage, 10-25% in bronchoalveolar lavage, 20-0% in bronchial brushing, 21-0% in transbronchial biopsy and 24-41% in postbronchoscopic sputum respectively. There is no statistically significant difference between the diagnostic values of the methods. FOB and related applications were usefull in pulmonary tuberculosis cases who could not expectorate and smear negative.

Kaynakça

  • 1. Schluger NW, Rom WN. Current approaches to the diagnosis of active pulmonary tuberculosis. Am J Respir Crit Care Med 1994; 149: 264-7.
  • 2. Ginesu F, Pirina P, Sechi LA, et al. Microbiological diagnosis of tuberculosis: a comparison of old and new methods. J Chemother 1998; 10: 295-300.
  • 3. Jett JR, Cortese DA, Dines DE. The value of bronchoscopy in the diagnosis of mycobacterial disease, a five year experience. Chest 1981; 80: 575-8.
  • 4. Willcox PA, Benatar SR, Potgieter PD. Use of flexible fibreoptic bronchoscope in diagnosis of sputum-negative pulmonary tuberculosis. Thorax 1982; 37: 598-601.
  • 5. Pant K, Chawla R, Mann PS, Jaggi OP. Fiberbronchoscopy in smear-negative miliary tuberculosis. Chest 1989; 95: 1151-2.
  • 6. Charoenratanakul S, Dejsomritrutai W, Chaipraseri A. Diagnostic role of fiberoptic bronchoscopy in suspected smear negative pulmonary tuberculosis. Respir Med 1995; 89: 621-3.
  • 7. Fujii H, Ishihara J, Fukaura A, et al. Early diagnosis of tuberculosis by fibreoptic bronchoscopy. Tuber Lung Dis 1992; 73: 167-9.
  • 8. Alp Aİ, Karlıkaya C, Hatipoğlu ON, ark. Yayma negatif akciğer tüberkülozunda fiberoptik bronkoskopinin tanısal değeri. Tüberküloz ve Toraks Dergisi 2002; 50: 278-87.
  • 9. Wallace JM, Deutsch AL, Harrell JH, Moser KM. Bronchoscopy and transbronchial biopsy in evaluation of patients with suspect active tuberculosis. Am J Med 1981; 70: 1189-94.
  • 10.Chan HS, Sun AJM, Hoheise GB. Bronchoscopic aspiration and bronchoalveolar lavage in the diagnosis of sputum smear-negative pulmonary tuberculosis. Lung 1990; 168: 215-20.
  • 11.Kennedy DJ, Lewis WP, Barnes PF. Yield of bronchoscopy for the diagnosis of tuberculosis in patients with human immunodeficiency virus infection. Chest 1992; 102: 1040-4.
  • 12.De Gracia J, Curull V, Vidal R, et al. Diagnostic value of bronchoalveolar lavage in suspected pulmonary tuberculosis. Chest 1988; 93: 329-32.
  • 13.Maartens G, Willcox A, Benatar SR. Miliary tuberculosis: rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults. Am J Med 1990; 89: 291-6.
  • 14.Chawla R, Pant K, Jaggi OP, et al. Fibreoptic bronchoscopy in smear-negative pulmonary tuberculosis. Eur Respir J 1988; 1: 804-6.
  • 15.Khoo KK, Meadway J. Fibreoptic bronchoscopy in rapid diagnosis of sputum smear negative pulmonary tuberculosis. Respir Med 1989; 83: 335-8.
  • 16.Palenque E, Amor E, Bernaldo de Quiros JC. Comparison of bronchial washing, brushing and biopsy for diagnosis of pulmonary tuberculosis. Eur J Clin Microbiol 1987; 6: 191-2.
  • 17.Miro AM, Gibilara E, Powell S, Skamholz SL. The role of fiberoptic bronchoscopy for diagnosis of pulmonary tuberculosis in patients at risk for AIDS. Chest 1992; 101: 1211-4.
  • 18.Russel MD, Torrington KG, Tenholder MF. A ten-year experience with fiberoptic bronchoscopy for mycobacterial isolation. Am Rev Respir Dis 1986; 133: 1069-71.
  • 19.Strange C, Barbarash RA, Heffner JE: Lidocaine concentrations in bronchoscopic specimens. Chest 1988; 93: 547-9.
  • 20.Caminero Luna JA, Rodrigez de Castro F, Campos-Herrero I, et al. The efficacy of bronchoalveolar lavage in the diagnosis of pulmonary tuberculosis. Arc Bronconeumol 1994; 30: 236-9.
  • 21.Baughman RP, Dohn MN, Loudon RG, Frame PT. Bronchoscopy and bronchoalveolar lavage in tuberculosis and fungal infections. Chest 1991; 99: 92-7.
  • 22.Funahashi A, Lohaus GH, Politis J, Hranicka LJ. Role of fiberoptic bronchoscopy in the diagnosis of mycobacterial disease. Thorax 1983; 38: 267-70.
  • 23.Masotti A, Rodella L, Inaspettato G, et al. Clinical and bronchoscopic features of endobronchial tuberculosis. Monaldi Arch Chest Dis 1995; 50: 89-92.

BALGAM ÇIKARAMAYAN VE YAYMA NEGATİF AKCİĞER TÜBERKÜLOZU OLGULARINDA FİBEROPTİK BRONKOSKOPİNİN TANISAL DEĞERİ

Yıl 2002, Cilt: 16 Sayı: 2, 1 - 14, 01.10.2002

Öz

Balgam çıkaramayan ve yayma negatif akciğer tüberkülozu olgularında fiberoptik bronkoskopi (FOB) ile yapılan uygulamaların tanısal değeri araştırıldı. 1995-1999 yılları arasında kliniklerimizde aktif akciğer tüberkülozu tanısı konulmuş ve tanı için FOB yapılmış 111 olgu çalışmaya alındı. Olguların 32'si balgam çıkaramayan, 79'u yayma negatifti. Bronkoskopi öncesi alınan mide suyu kültürlerinde %7 (2/32), balgam kültürlerinde %33 (26/79) olmak üzere toplam %25 (28/111) olguda kültür pozitifliği saptandı. FOB ile 40 (%36) olguya erken tanı konuldu. FOB toplam 64 (%56) olguda tanısaldı. FOB ile yapılan uygulamaların yayma ve kültür pozitiflik oranları sırasıyla, bronş lavajı %16-31, bronkoalveoler lavaj %10-25, bronşiyal fırçalama %20-0, transbronşiyal biyopsi %21-0 ve post bronkoskopik balgam %24-41 olarak saptandı. Uygulanan yöntemlerin tanısal verimlilikleri arasında istatistiksel olarak anlamlı fark saptanmadı. FOB ile yapılan uygulamaların balgam çıkaramayan ve yayma negatif akciğer tüberkülozu olgularında tanısal yarar sağladığı sonucuna varıldı.

Kaynakça

  • 1. Schluger NW, Rom WN. Current approaches to the diagnosis of active pulmonary tuberculosis. Am J Respir Crit Care Med 1994; 149: 264-7.
  • 2. Ginesu F, Pirina P, Sechi LA, et al. Microbiological diagnosis of tuberculosis: a comparison of old and new methods. J Chemother 1998; 10: 295-300.
  • 3. Jett JR, Cortese DA, Dines DE. The value of bronchoscopy in the diagnosis of mycobacterial disease, a five year experience. Chest 1981; 80: 575-8.
  • 4. Willcox PA, Benatar SR, Potgieter PD. Use of flexible fibreoptic bronchoscope in diagnosis of sputum-negative pulmonary tuberculosis. Thorax 1982; 37: 598-601.
  • 5. Pant K, Chawla R, Mann PS, Jaggi OP. Fiberbronchoscopy in smear-negative miliary tuberculosis. Chest 1989; 95: 1151-2.
  • 6. Charoenratanakul S, Dejsomritrutai W, Chaipraseri A. Diagnostic role of fiberoptic bronchoscopy in suspected smear negative pulmonary tuberculosis. Respir Med 1995; 89: 621-3.
  • 7. Fujii H, Ishihara J, Fukaura A, et al. Early diagnosis of tuberculosis by fibreoptic bronchoscopy. Tuber Lung Dis 1992; 73: 167-9.
  • 8. Alp Aİ, Karlıkaya C, Hatipoğlu ON, ark. Yayma negatif akciğer tüberkülozunda fiberoptik bronkoskopinin tanısal değeri. Tüberküloz ve Toraks Dergisi 2002; 50: 278-87.
  • 9. Wallace JM, Deutsch AL, Harrell JH, Moser KM. Bronchoscopy and transbronchial biopsy in evaluation of patients with suspect active tuberculosis. Am J Med 1981; 70: 1189-94.
  • 10.Chan HS, Sun AJM, Hoheise GB. Bronchoscopic aspiration and bronchoalveolar lavage in the diagnosis of sputum smear-negative pulmonary tuberculosis. Lung 1990; 168: 215-20.
  • 11.Kennedy DJ, Lewis WP, Barnes PF. Yield of bronchoscopy for the diagnosis of tuberculosis in patients with human immunodeficiency virus infection. Chest 1992; 102: 1040-4.
  • 12.De Gracia J, Curull V, Vidal R, et al. Diagnostic value of bronchoalveolar lavage in suspected pulmonary tuberculosis. Chest 1988; 93: 329-32.
  • 13.Maartens G, Willcox A, Benatar SR. Miliary tuberculosis: rapid diagnosis, hematologic abnormalities, and outcome in 109 treated adults. Am J Med 1990; 89: 291-6.
  • 14.Chawla R, Pant K, Jaggi OP, et al. Fibreoptic bronchoscopy in smear-negative pulmonary tuberculosis. Eur Respir J 1988; 1: 804-6.
  • 15.Khoo KK, Meadway J. Fibreoptic bronchoscopy in rapid diagnosis of sputum smear negative pulmonary tuberculosis. Respir Med 1989; 83: 335-8.
  • 16.Palenque E, Amor E, Bernaldo de Quiros JC. Comparison of bronchial washing, brushing and biopsy for diagnosis of pulmonary tuberculosis. Eur J Clin Microbiol 1987; 6: 191-2.
  • 17.Miro AM, Gibilara E, Powell S, Skamholz SL. The role of fiberoptic bronchoscopy for diagnosis of pulmonary tuberculosis in patients at risk for AIDS. Chest 1992; 101: 1211-4.
  • 18.Russel MD, Torrington KG, Tenholder MF. A ten-year experience with fiberoptic bronchoscopy for mycobacterial isolation. Am Rev Respir Dis 1986; 133: 1069-71.
  • 19.Strange C, Barbarash RA, Heffner JE: Lidocaine concentrations in bronchoscopic specimens. Chest 1988; 93: 547-9.
  • 20.Caminero Luna JA, Rodrigez de Castro F, Campos-Herrero I, et al. The efficacy of bronchoalveolar lavage in the diagnosis of pulmonary tuberculosis. Arc Bronconeumol 1994; 30: 236-9.
  • 21.Baughman RP, Dohn MN, Loudon RG, Frame PT. Bronchoscopy and bronchoalveolar lavage in tuberculosis and fungal infections. Chest 1991; 99: 92-7.
  • 22.Funahashi A, Lohaus GH, Politis J, Hranicka LJ. Role of fiberoptic bronchoscopy in the diagnosis of mycobacterial disease. Thorax 1983; 38: 267-70.
  • 23.Masotti A, Rodella L, Inaspettato G, et al. Clinical and bronchoscopic features of endobronchial tuberculosis. Monaldi Arch Chest Dis 1995; 50: 89-92.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA47AY89PK
Bölüm Araştırma Makalesi
Yazarlar

Ali Kömürcüoğlu Bu kişi benim

Gülru Polat Bu kişi benim

Gülay Utkaner Bu kişi benim

Sabri Kalenci Bu kişi benim

Gültekin Tibet Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2002
Yayımlandığı Sayı Yıl 2002 Cilt: 16 Sayı: 2

Kaynak Göster

APA Kömürcüoğlu, A., Polat, G., Utkaner, G., Kalenci, S., vd. (2002). BALGAM ÇIKARAMAYAN VE YAYMA NEGATİF AKCİĞER TÜBERKÜLOZU OLGULARINDA FİBEROPTİK BRONKOSKOPİNİN TANISAL DEĞERİ. İzmir Göğüs Hastanesi Dergisi, 16(2), 1-14.