BibTex RIS Kaynak Göster

TEK TARAFLI HİPERİNFLASYONA NEDEN OLAN PULMONER MALT LENFOMA (OLGU SUNUMU)

Yıl 2002, Cilt: 16 Sayı: 2, 0 - 0, 01.10.2002

Öz

İlk olarak 1983'de Isaacson ve Wright tarafından tanımlanmış olan MALT (mukoza ile ilişkili lenfoid doku kökenli) lymphoma, ekstranodal lenfomaların en sık görülen formudur.Sadece midede değil çeşitli gastrointestinal sistem dışı organlarda da görülebilir. Son bir yıldır nefes darlığından yakınan otuz iki yaşında kadın olgu astım bronşiyale düşünülerek tedavi edilmişi di. Akciğer grafisinde; mediasten ve kalpte sağa doğru yer değiştirme, sol akciğer de hiperinflasyon, solunum fonksiyon testlerinde hafif restriktif bozukluk saptandı. Toraksspiral tomografisinde;sol ana bronşu, karinadan itibaren beş santimlik segment boyunca daraltan kitle izlendi. Fiberoptik bronkoskopide; sol ana bronş girişini tama yakın tıkayan, milimetrik polipoid lezyonlar görüldü.Bronkoskopik biopside mukozayı tamamen örten lenfositlerden oluşan monoton hücre infiltrasyonu izlendi. Histopatolojik ve immünhistokimyasal olarak düşük dereceli MALT lenfoma teşhis edildi. Kemoterapiye iyi yanıt alınan olgu tedavisiz radyolojik takibe alındı. Ana bronş obstrüksiyonu ve tek taraflı hiperinflasyona neden olan, sadece akciğer lokalizasyonlu MALT lenfoma olgusunu literatür bilgileri eşliğinde sunduk.

Kaynakça

  • 1. Salhany KE, Pietra GG. Lymphoproliferative and hematologic diseases involving the lung. In: Fishman AP (ed). Fishman’s pulmonary diseases and disorders. New York: Mc. GrawHill Book Company; 1998: 1861-79.
  • 2. Besien KV, Cabanillas F. Clinical manifestations, staging, and treatment of non-hodgkin lymphoma. In: Hoffman V, Benz EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P (eds). Hematology basic principles and practice. Philadelphia: Churchill Livingstone; 2000: 1293- 339.
  • 3. Wislez M, Cadranel J, Antoine M et al. Lymphoma of pulmonary mucosa-associated lymphoid tissue: CT scan findings and pathological correlations. Eur Respir J 1999; 14: 423-9.
  • 4. Cavalli F, Isaacson PG et al. MALT lymphomas. Hematology 2001; 1: 241-58.
  • 5. Thieblemont C, Berger F et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood 2000; 95(3): 802-6.
  • 6. Center DM, Berman JS. Lymhocyte- and macrophagemediated inflammation in the lung. In: Fishman AP (ed). Fishman’s pulmonary diseases and disorders. New York: Mc. GrawHill Book Company; 1998: 275-87.
  • 7. Sato A. Basic and clinical aspects of bronchus-associated lymphoid tissue. Nihon Kokyuki Gakkai Zasshi 2000; 38(1): 3-11.
  • 8. Richmond I, Pritchard GE, Ashcroft T et al. Bronchus associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non-smokers. Thorax 1993; 48: 1130-4.
  • 9. Ren Y, Raitz EN, Lee KR et al. Pulmonary small lymphocytic lymphoma (mucosa-associated lymphoid tissue type) associated with pulmonary hyalinizing granuloma. Chest 2001; 120: 1027-30.
  • 10. Liaw YS, Yang PC, Su IJ et al. Mucosa-associated lymphoid tissue lymphoma of the lung with cold reacting autoantibody-mediated hemolytic anemi. Chest 1994; 105: 288-90.
  • 11. King LJ, Padley SPG, Wotherspoon AC, Nicholson AG. Pulmonary MALT lymphoma: imaging findings in 24 cases. Eur Radiol 2000; 10: 1932-8.
  • 12. McCulloch GL, Sinnatamby R et al. High resolution computed tomographic appearance of MALToma of the lung. Eur Radiol 1998; 8: 1669-73.
  • 13. Poletti V, Romagna M et al. Bronchoalveolar lavage in the diagnosis of low grade, MALT type, B-cell lymphoma in the lung. Monaldi Arch Chest Dis 1995; 50(3): 191-4.
  • 14. Zinzani PL, Magagnoli M et al. Nongastrointestinal low grade mucosa associated lymphoid tissue lymphoma: Analysis of 75 patients. J Clin Oncology 1999; 17(4): 1254.

PULMONARY MALT LYMPHOMA CAUSING UNILATERAL HYPERINFLATION (CASE REPORT)

Yıl 2002, Cilt: 16 Sayı: 2, 0 - 0, 01.10.2002

Öz

Mucosa-associated lymphoid tissue-derived lymphoma (MALT lymphoma), first described in 1983 by Isaacson and Wright, is the most common subset of the extranodal lymphomas. They arise not only from the stomach but also from various nongastrointestinal sites. Thirty two years old woman, who suffers from breathlessness for one year had been treated for asthma bronchiale. In chest roentgenogram; mediastinum and heart transposition to the right side, hiperinflation of the left lung, moderate restriction in respiratory function tests. In thorax spiral tomography; a mass narrowing left main bronchi, along a five centimeters part from carina, was seen. Fiberoptic bronchoscopy revealed milimetric polypoid lesions those nearly total obstructed left main bronchi. Bronchoscopic biopsy showed monotone cell infiltration that formed with lymphocytes covering mucosa totally. MALT lymphoma was diagnosed histopathology and immunhistopathology. The response to chemotherapy was good and it was planned to follow her without treatment. A case, having MALT lymphoma only being established in lung, causing main bronchi obstruction and unilateral hiperinflation, was presented with literature.

Kaynakça

  • 1. Salhany KE, Pietra GG. Lymphoproliferative and hematologic diseases involving the lung. In: Fishman AP (ed). Fishman’s pulmonary diseases and disorders. New York: Mc. GrawHill Book Company; 1998: 1861-79.
  • 2. Besien KV, Cabanillas F. Clinical manifestations, staging, and treatment of non-hodgkin lymphoma. In: Hoffman V, Benz EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P (eds). Hematology basic principles and practice. Philadelphia: Churchill Livingstone; 2000: 1293- 339.
  • 3. Wislez M, Cadranel J, Antoine M et al. Lymphoma of pulmonary mucosa-associated lymphoid tissue: CT scan findings and pathological correlations. Eur Respir J 1999; 14: 423-9.
  • 4. Cavalli F, Isaacson PG et al. MALT lymphomas. Hematology 2001; 1: 241-58.
  • 5. Thieblemont C, Berger F et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood 2000; 95(3): 802-6.
  • 6. Center DM, Berman JS. Lymhocyte- and macrophagemediated inflammation in the lung. In: Fishman AP (ed). Fishman’s pulmonary diseases and disorders. New York: Mc. GrawHill Book Company; 1998: 275-87.
  • 7. Sato A. Basic and clinical aspects of bronchus-associated lymphoid tissue. Nihon Kokyuki Gakkai Zasshi 2000; 38(1): 3-11.
  • 8. Richmond I, Pritchard GE, Ashcroft T et al. Bronchus associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non-smokers. Thorax 1993; 48: 1130-4.
  • 9. Ren Y, Raitz EN, Lee KR et al. Pulmonary small lymphocytic lymphoma (mucosa-associated lymphoid tissue type) associated with pulmonary hyalinizing granuloma. Chest 2001; 120: 1027-30.
  • 10. Liaw YS, Yang PC, Su IJ et al. Mucosa-associated lymphoid tissue lymphoma of the lung with cold reacting autoantibody-mediated hemolytic anemi. Chest 1994; 105: 288-90.
  • 11. King LJ, Padley SPG, Wotherspoon AC, Nicholson AG. Pulmonary MALT lymphoma: imaging findings in 24 cases. Eur Radiol 2000; 10: 1932-8.
  • 12. McCulloch GL, Sinnatamby R et al. High resolution computed tomographic appearance of MALToma of the lung. Eur Radiol 1998; 8: 1669-73.
  • 13. Poletti V, Romagna M et al. Bronchoalveolar lavage in the diagnosis of low grade, MALT type, B-cell lymphoma in the lung. Monaldi Arch Chest Dis 1995; 50(3): 191-4.
  • 14. Zinzani PL, Magagnoli M et al. Nongastrointestinal low grade mucosa associated lymphoid tissue lymphoma: Analysis of 75 patients. J Clin Oncology 1999; 17(4): 1254.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA74PS57KT
Bölüm Olgu Sunumu
Yazarlar

Dr. Ahmet Emin Erbaycu Bu kişi benim

Dr. İşıl Karasu Bu kişi benim

Dr. Füsun Özdemir Kıran Bu kişi benim

Dr. Nur Yücel Bu kişi benim

Dr. Ayşe Özsöz Bu kişi benim

Dr. Oktay Bilger Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2002
Yayımlandığı Sayı Yıl 2002 Cilt: 16 Sayı: 2

Kaynak Göster

APA Erbaycu, D. A. E., Karasu, D. İ., Kıran, D. . F. Ö., Yücel, D. N., vd. (2002). TEK TARAFLI HİPERİNFLASYONA NEDEN OLAN PULMONER MALT LENFOMA (OLGU SUNUMU). İzmir Göğüs Hastanesi Dergisi, 16(2).