Öz
Akciğerin primer tükrük bezi benzeri tümörü oldukça nadir görülür. Bu tip tümörler submukozal bronşial bezlerden orijin alırlar. Çoğunlukla ana bronşta lokalizedirler. Komplet rezeksiyon önerilen tedavi şeklidir. Adjuvan radyoterapi veya kemoterapi verilebilir. Kırkdört yaşında erkek olgu sağ omuz ve sırt ağrısı, hemoptizi ve nefes darlığı yakınmaları ile başvurdu. Posteroanterior akciğer grafisinde sağ akciğer üst zonda homojen dansite artışı izlendi. Toraks bilgisayarlı tomografisinde sağ apekste mediasten ve ana vasküler yapılara invaze tümöral lezyon ve bilateral multipl hematojen metastaz ile uyumlu lezyonlar saptandı. Bronkoskopide trakea alt uçtan başlayan sağ ana bronş girişinde submukozal tümöral infiltrasyon ve sağ üst lob bronş lümenini daraltan kitle lezyonu izlendi. Histopatolojk ve immunohistokimyasal inceleme sonucu akciğerin tükrük bezi benzeri tümörü olarak rapor edildi. Uzak metastazı saptanmayan ve Evre 4 olarak evrelendirilen olguya cisplatin bazlı kemoterapi verildi. Olgumuz nadir görülmesi nedeniyle literatür bilgileri eşliğinde sunulmuştur.
Anahtar Kelimeler
Tükrük bezi benzeri tümör akciğer immunohistokimyasal boyama
Kaynakça
- Moran CA. Primary salivary gland-type tumors of the lung. Semin Diagn Pathol 1995; 2: 106-22.
- Bennett AK, Mills SE, Wick MR. Salivary-type neoplasms of the breast and lung. Semin Diagn Pathol 2003; 20: 279-304.
- Moran CA, Suster S, Aksin FB, Koss MN. Benign and malignant salivary gland-type mixed tumors of the lung. Clinicopathologic and immuno- histochemical study of eight cases. Cancer 1994; 73: 2481-90.
- Rosai J. Ackerman’s Surgical Pathology . 9th ed. St Louis, Mosby 2004: 406-7.
- Carretta A, Libretti L, Taccagni G, Zannini P. Salivary gland-type mixed tumor (pleomorphic adenoma) of the lung. Interact CardioVasc Thorac Surg 2004; 3: 663-5.
- Wilson RW, Moran CA. Epithelial-myoepithelial carcinoma of the lung: Immunohistochemical and ultrastructural observations and review of the literature. Hum Pathol 1997; 28: 631-5.
- Matsumoto M, Sonobe H, Furihata M, Nonami Y, Ohmori Y, Ohtsuki Y. A case of Salivary gland- type mixed tumor of the lung differentiating toward type II alveolar Epithelial cells in glan- dular components with a literature review. Virchows Arch 2002; 441: 618-21.
- Yazıcı Ü, Topçu S, Altınok T, Kurul C, Alper A, Sarıca E, Tafltepe İ. Trakea ve Ana Bronflların Adenoid Kistik Karsinomu. Toraks Dergisi 2003; 4: 69-72. Yazıflma Adresi: Dr. Günseli BALCI
- Dr. Suat Seren Göğüs Hastalıkları ve Cerrahisi
- Eğitim ve Arafltırma Hastanesi, Göğüs Hastalıkları
- Bölümü, Yeniflehir / İZMİR
- e-posta: dr_gunselibalci@yahoo.com
Öz
Salivary gland type tumor primarily arising in the lung is extremely rare. These types of tumors originate from submucosal bronchial glands. Most of them are located within the main bronchus. Complete surgical resection is recommended for treatment of this tumor usually followed by adjuvant radiation or chemotherapy. The patient is a 44-years-old man applied with complaints of right shoulder and right sided back pain, hemoptysis and shortness of breath. There was homogenius lesion in right upper lobe on posterior-anterior chest radiography. The right upper lobe contained a tumor mass extending into the large vessels and the mediastinum on thorax computerized tomography. Bilateral multipl pulmonary paranchymal metastasis were identified radiographically. In bronchoscopy, tumoral lesion that is starting from the proximal portion of the trakea and causing submucosal tumoral infiltration in right main bronchus and narrowing the lumen of right upper lobe bronchus was seen. Primary salivary gland type tumor of lung was reported in histopathological and immuno¬histochemical examination of biopsy that was taken from this regions. There were no distant metastasis. The case was accepted as stage 4 and received cisplatin based chemotheraphy. The case was presented with the review of literature as a rare entity.
Anahtar Kelimeler
Kaynakça
- Moran CA. Primary salivary gland-type tumors of the lung. Semin Diagn Pathol 1995; 2: 106-22.
- Bennett AK, Mills SE, Wick MR. Salivary-type neoplasms of the breast and lung. Semin Diagn Pathol 2003; 20: 279-304.
- Moran CA, Suster S, Aksin FB, Koss MN. Benign and malignant salivary gland-type mixed tumors of the lung. Clinicopathologic and immuno- histochemical study of eight cases. Cancer 1994; 73: 2481-90.
- Rosai J. Ackerman’s Surgical Pathology . 9th ed. St Louis, Mosby 2004: 406-7.
- Carretta A, Libretti L, Taccagni G, Zannini P. Salivary gland-type mixed tumor (pleomorphic adenoma) of the lung. Interact CardioVasc Thorac Surg 2004; 3: 663-5.
- Wilson RW, Moran CA. Epithelial-myoepithelial carcinoma of the lung: Immunohistochemical and ultrastructural observations and review of the literature. Hum Pathol 1997; 28: 631-5.
- Matsumoto M, Sonobe H, Furihata M, Nonami Y, Ohmori Y, Ohtsuki Y. A case of Salivary gland- type mixed tumor of the lung differentiating toward type II alveolar Epithelial cells in glan- dular components with a literature review. Virchows Arch 2002; 441: 618-21.
- Yazıcı Ü, Topçu S, Altınok T, Kurul C, Alper A, Sarıca E, Tafltepe İ. Trakea ve Ana Bronflların Adenoid Kistik Karsinomu. Toraks Dergisi 2003; 4: 69-72. Yazıflma Adresi: Dr. Günseli BALCI
- Dr. Suat Seren Göğüs Hastalıkları ve Cerrahisi
- Eğitim ve Arafltırma Hastanesi, Göğüs Hastalıkları
- Bölümü, Yeniflehir / İZMİR
- e-posta: dr_gunselibalci@yahoo.com
Ayrıntılar
| Diğer ID | JA85SF96HC |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Aralık 2008 |
| Yayımlandığı Sayı | Yıl 2008 Cilt: 22 Sayı: 3 |