TİP II DİYABETLİ HASTALARDA SOLUNUM FONKSİYONLARI VE DİYABET KONTROLÜ ARASINDAKİ İLİŞKİ

Yıl 2011, Cilt: 25 Sayı: 2, 101 - 106, 01.10.2011

Erkan Ceylan Mehmet Nuri Turan Faruk Günak

Öz

-

Anahtar Kelimeler

Diyabetes mellitus, difüzyon kapasitesi, solunum fonksiyon testi

RELATIONSHIP BETWEEN DIABETES CONTROL AND PULMONARY FUNCTIONS WITH TYPE II DIABETES MELLITUS PATIENTS

Öz

The lungs ar e affected as a result of the widespread microvascular changes in the patients of Diabetes mellitus. The relations of this effect among respiratory functions control of DM and survey time were explored. 37 cases with DM and 25 healthy control cases of the same age group were recruited in the study. Respiratory function tests and carbon monoxide diffusion capacity (DLCO) measurement were performed in all cases. HbA1c level was high in 24 diabetic cases (15%±1.3) with respiratory function abnormalities. Duration in diabetic patients of the disease was 7±5.1 years. Although restrictive type disorders were detected in 24 (65%) of 37 diabetic patients none of the cases had obstructive type respiratory disorder. With high levels of HbA1c in diabetic patients, found a lower DLCO values.

Anahtar Kelimeler

Diabetes mellitus, diffusing capacity, pulmonary function test

Kaynakça

• 1. Boulbou MS, Gourgoulianis KI, Klisiaris VK, Tsikrikas TS, Stathakis NE, Molyvdas PA. Diabetes mellitus and lung function. Med Princ Pract 2003; 12: 87-91.
• 2. American Thoracic Society. Standardization of spirometry: 1987 update. Am Rev Respir Dis 1987; 136: 1286–96.
• 3. American Thoracic Society. Single-breath carbon monoxide diffusing capacity (transfer factor). Recommendations for a standard technique 1995 update. Am J Respir Crit Care Med 1995; 152: 2185-98.
• 4. Hsia CC, Raskin P. The diabetic lung: relevance of alveolar microangiopathy for the use of inhaled insulin. Am J Med 2005; 118: 205-11.
• 5. Erdo¤an BB, Uzaslan E. Diabet ve Akci¤er. Uluda¤ Üniversitesi T›p Fakültesi Dergisi 2005; 31: 71-74.
• 6. Weynand B, Jonckheere A, Frans A, Rahier J. Diabetes mellitus induces a thickening of the pulmonary basal lamina.Respiration 1999; 66: 14-9.
• 7. Scano G, Filippelli M, Romagnoli I, Mancini M, Misuri G, Duranti R, Rosi E. Hypoxic and hypercapnic breathlessness inpatients with type 1 diabetes mellitus. Chest 2000; 117: 960-7.
• 8. Turaçlar UT, Candan F, Sümer H. Tip 2 diyabetik hastalarda solunum fonksiyon testleri. Tüberküloz ve Toraks Dergisi 1999; 47: 54-7.
• 9. Weir DC, Jennings PE, Hendy MS, et al. Transfer factor for carbon monoxide in patients with diabetes with and without microangiopathy. Thorax 1988; 43: 725-6.
• 10. Çelik P, Özmen B, Yorganc›o¤lu A, Özmen D. Pulmonary function parameters in patients with diabetes mellitus. Turkish J of End and Metab 1999; 1: 5-10.
• 11. Genç H, Müftüo¤lu O, Kayatürk N. Diabetes mellitusta akci¤er fonksiyonlar›. Türk Diyabet Y›ll›¤› 1988-1989; 295-305.
• 12. fienyi¤it A, Söker M, Asan E, Leblebici ‹H. Tip 1 Diyabetli Çocuklarda Solunum Fonksiyonlar›nda Saptanan Bozukluklar ile Bunun Diyabet Kontrolü ve Hastal›k Süresi ile ‹liflkisi. Tüberküloz ve Toraks Dergisi 2002; 50: 351-357.
• 13. Ar› G, ‹til O,Çömlekçi A, Özdo¤an Ö, De¤irmenci B, Yeflil S, Akkoçlu A. Tip 2 Diabetes Mellituslu Hastalarda Solunum Fonksiyon Testi ve ‹nhalasyon Perfüzyon Sintigrafisi Bulgular›. Toraks Dergisi 2002; 3: 257-265
• 14. Lange P, Groth S, Kastrup J, Mortensen J, Appleyard M, Nyboe J, Jensen G, Schnohr P. Diabetes mellitus, plasma glucose and lung function in a cross-sectional population study. Eur Respir J 1989; 2: 14-9.
• 15. Ramirez LC, Dal Nogare A, Hsia C, Arauz C, Butt I, Strowig SM, Schnurr-Breen L, Raskin P. Relationship between diabetes control and pulmonary function in insulin-dependent diabetes mellitus. Am J Med 1991; 91: 371-6.
• 16. Mori H, Okubo M, Okamura M, Yamane K, Kado S, Egusa G, Hiramoto T, Hara H, Yamakido M. Abnormalities of pulmonary function in patients with noninsulin-dependent diabetes mellitus. Internal Medicine 1992; 31: 189-93.
• 17. Sandler M, Bunn AE, Steward RI. Pulmonary function in young insulin-dependent diabetic subjects. Chest 1986; 90: 670-5.
• 18. Innocenti F, Fabbri A, Anichini R, Tuci S, Pettinà G, Vannucci F, De Giorgio LA, Seghieri G. Indications of reduced pulmonary function in type 1 (insulin-dependent) Diabetes mellitus. Diabetes Res Clin Pract 1994; 25: 161-8.
• 19. Sandler M, Bunn AE, Steward RI. Cross-section study of pulmonary function in patients with insulin-dependent diabetes mellitus. Am Rev Respir Dis 1987; 135: 223-9.