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Retrospective Examination of İntracranial Metastasis Tumors

Yıl 2021, Cilt: 7 Sayı: 1, 56 - 72, 01.01.2021

Öz

Background: In our study, we aimed to investigate the effects of clinical and imaging findings on the survival of patients with intracranial metastasis.

Materials-Methods: Data of 66 patients with intracranial metastases who applied to Mersin University Faculty of Medicine, Brain and Nerve Surgery outpatient clinic and Emergency Department between January 1, 2009 and November 10, 2013 were retrospectively analyzed.

Result: Of the patients, 39 (59.1%) were male and 27 (40.9%) were female. The average age of the patients was 57 years. Among the cases, 29 (43.9%) lung cancer, 6 (9.2%) malignant melanoma, 5 (7.5%) gastrointestinal system tumors, 4 (6.1%) lymphoma, 10 (15.2%) other tumors (renal cell ca, testicular ca, ovarian ca, bladder ca) were present. Metastasis caused by cancer of unknown primary was detected in 3 (4.5%) of the patients. It was found that 36 (54.6%) of metastases were solitary and 30 (45.4%) were multiple. The brain metastases, 47 (71%) were supratentorial, 12 (18%) were infratentorial, 7 (11%) were both supratentorial and infratentorial. 30 (45.5%) of the patients were treated surgically. Surgical treatment was not applied to 36 (54.5%) patients. The average survival of multiple metastases was 6.1 months, and 8.4 months for solitary metastases. The mean life expectancy was found to be 8.7 months in patients who underwent surgical treatment and 5.6 months in patients who did not undergo surgical treatment.

Conclusion: Factors such as the patient's general condition, neurological condition, and the types of treatment administered affect their lifespan.

Kaynakça

  • 1- Thomas SS, Dunbar EM. Modern Multidisciplinary Management of Brain Metastasis. Curr Oncol Rep 2010;12:34-40.
  • 2- Lin NU, Bellon JR, Winer EP. CNS metastasis in breast cancer. J Clin Oncol 2004;22:3608-3617.
  • 3- K. Ogawa, Y. Yoshii, Y. Aoki et al., “Treatment and prognosis of brain metastasis from gynecological cancers,” Neurologia Medico-Chirurgica, 2008, vol. 48, no. 2, pp. 57–62
  • 4- Graus F, Walker RW, Allen JC: Brain metastasis in children. J Pediatri 1983; 103:558-561
  • 5- Delattre JY, Krol G, Thaler HT, Posner JB. Distribution of brain metastasis. Arch Neurol. 1988;45:741–4
  • 6- Sawaya R, Bindal RK, Lang FF, et al: Metastatic brain tumors. In Kaye AH, Laws ER (eds): Brain Tumors. An Encyclopedic Approach, 2nd ed. Edinburgh, Churchill Livingstone, 2001:999-1026
  • 7- Macchiarini P, Bounaguid IR, Hardin M, et al.: Results and prognosis factors of surgery in the management of non smallcell lung cancer with solitary brain metastasis.Cancer 1991; 68:300-304
  • 8- Loeffler J.S, Patchell R.A, Sawaya R. Metastatic Brain Cancer: Principles and Practice of Oncology 5th Edition Philadelphia, Lippincot-Raven 1997, 2523-2536
  • 9- Nutt S.H, Patchell R.A, İntrakranial Hemorrhage Associated with Primary and Secondary Tumors Neurosurg Clin. North Am, 2008, 3:591-605,192
  • 10- Kizir A,Küçücük S. Onkolojik aciller II (Radyasyon onkolojisinde aciller). In: Topuz E, Aydıner A, Karadeniz AN, eds. Klinik Onkoloji. İstanbul: İ.Ü Onkoloji Enstitüsü Yayınları, 1.Baskı, 2004. P.305-10
  • 11- Ranasinghe MG,sheehan JM. Surgical management of brain metastasis. Neurosurg Focus.2007; 22(3):E2
  • 12- Mehta M, Tremont-Lukats IW. Evaluating and management of brain metastasis. In: Pery MC, ed. American Society of Clinical Oncology Educational Book, 2002:375-82
  • 13- Yokoi K, Kamiya N, Matsuguma H, et al. Detection of brain metastasis in patentially operable non-small cell lung cancer. 1999; 115:714-19
  • 14- Bergqvist MM, Brattsrom D, Bennmarker H, et al. Irradiation of brain metastasis from lung cancer: A retrospective study. Lung Cancer 1998;20:57-6
  • 15- Kula Ö, Bayrak Kula N, Bayram H ve ark. Primer akciğer kanserlerinde beyin metastazları. 20. Yıl Akciğer Günleri Kongre Kitabı. Bursa: Uludağ Üniversitesi Yayınları, 1995;147-52
  • 16- Hsiung CY, Leung SW, Wang CJ, et al. THA prognostic factors of lung cancer patients with brain metastasis treated with radiotherapy. Journal of Neuro-Oncology 1998;36:71-7
  • 17- Olak J, Ferguson MK. Surgical management of second primary and metastatic lung cancer. In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, Minna JD, eds. Lung cancer: Principles and practice. Philadelphia: Lippincott Williams & Wilkins, 2000:730-41
  • 18- Pachell RA. Treatment of brain metastasis. In: Pery MC. American Society of Clinical Oncology Educational Book, 2002: 83-91
  • 19- Ferrigno D, Buccheri G. Cranial computed tomography as a part of the initial staging procedures for patients with non-small-cell lung cancer. Chest 1994;106:1025-9
  • 20- Bonette P, Puyo P, Gabriel C, et al. Surgical management of non-small cell lung cancer with synchronous brain metastasis. Chest 2001;119:1469-75
  • 21- Spiro SG, Porter JC. Lung cancer-where are we today? Current advances in staging and nonsurgical treatment.Am J Respir Crit Care Med 2002;166:1166-96
  • 22- Yılmaz U, Ediboğlu H, Yasan H ve ark. Küçük hücreli dışı akciğer kanserinin başlangıç evrelemesinde bilgisayarlı beyin tomografisi. Solunum Hastalıkları 1998;9:443-51
  • 23- Rodrigus P, de Brouwer P, Raoymakers E. Brain metastasis and non-small cell lung cancer. Prognostic factors and correlation with survival after irradiation. Lung Cancer 2001;32:129-36
  • 24- Penel N, Birchet A, Prevost B, et al. Prognostic factors of synchronous brain metastasis from lung cancer. Lung Cancer 2001;33:143-54
  • 25- Lagerwaard FJ, Lavendag PC, Nowak PJ, et al. Identification of prognostic factors in patients with brain metastasis: A review of 1292 patients. Int J Radiat Oncol Biol Phys 1999;43:795-803
  • 26- Shadidi H, Kvale PA. Long-term survival following surgical treatment of solitary brain metastasis in non-smallcell lung cancer. Chest 1996;109:271-6
  • 27- Kelly K, Bunn Jr PA. Is it time to re evaluate our approach to the treatment of brain metastasis in patients with non-small cell lung cancerLung Cancer 1998;20:85-91
  • 28- Keime-Guibert F, Napolitano M, Delattre JY. Neurological complications of radiotherapy and chemotherapy. J Neurol 1998; 245:695-708
  • 29- Lee AW, Kwong DL, Leung SF, et al. Factors affecting risk of symptomatic temporal lobe necrosis: Significance of fractional dose and treatment time. Int J Radiat Oncol Biol Phys 2002, 53:75-85
Yıl 2021, Cilt: 7 Sayı: 1, 56 - 72, 01.01.2021

Öz

Kaynakça

  • 1- Thomas SS, Dunbar EM. Modern Multidisciplinary Management of Brain Metastasis. Curr Oncol Rep 2010;12:34-40.
  • 2- Lin NU, Bellon JR, Winer EP. CNS metastasis in breast cancer. J Clin Oncol 2004;22:3608-3617.
  • 3- K. Ogawa, Y. Yoshii, Y. Aoki et al., “Treatment and prognosis of brain metastasis from gynecological cancers,” Neurologia Medico-Chirurgica, 2008, vol. 48, no. 2, pp. 57–62
  • 4- Graus F, Walker RW, Allen JC: Brain metastasis in children. J Pediatri 1983; 103:558-561
  • 5- Delattre JY, Krol G, Thaler HT, Posner JB. Distribution of brain metastasis. Arch Neurol. 1988;45:741–4
  • 6- Sawaya R, Bindal RK, Lang FF, et al: Metastatic brain tumors. In Kaye AH, Laws ER (eds): Brain Tumors. An Encyclopedic Approach, 2nd ed. Edinburgh, Churchill Livingstone, 2001:999-1026
  • 7- Macchiarini P, Bounaguid IR, Hardin M, et al.: Results and prognosis factors of surgery in the management of non smallcell lung cancer with solitary brain metastasis.Cancer 1991; 68:300-304
  • 8- Loeffler J.S, Patchell R.A, Sawaya R. Metastatic Brain Cancer: Principles and Practice of Oncology 5th Edition Philadelphia, Lippincot-Raven 1997, 2523-2536
  • 9- Nutt S.H, Patchell R.A, İntrakranial Hemorrhage Associated with Primary and Secondary Tumors Neurosurg Clin. North Am, 2008, 3:591-605,192
  • 10- Kizir A,Küçücük S. Onkolojik aciller II (Radyasyon onkolojisinde aciller). In: Topuz E, Aydıner A, Karadeniz AN, eds. Klinik Onkoloji. İstanbul: İ.Ü Onkoloji Enstitüsü Yayınları, 1.Baskı, 2004. P.305-10
  • 11- Ranasinghe MG,sheehan JM. Surgical management of brain metastasis. Neurosurg Focus.2007; 22(3):E2
  • 12- Mehta M, Tremont-Lukats IW. Evaluating and management of brain metastasis. In: Pery MC, ed. American Society of Clinical Oncology Educational Book, 2002:375-82
  • 13- Yokoi K, Kamiya N, Matsuguma H, et al. Detection of brain metastasis in patentially operable non-small cell lung cancer. 1999; 115:714-19
  • 14- Bergqvist MM, Brattsrom D, Bennmarker H, et al. Irradiation of brain metastasis from lung cancer: A retrospective study. Lung Cancer 1998;20:57-6
  • 15- Kula Ö, Bayrak Kula N, Bayram H ve ark. Primer akciğer kanserlerinde beyin metastazları. 20. Yıl Akciğer Günleri Kongre Kitabı. Bursa: Uludağ Üniversitesi Yayınları, 1995;147-52
  • 16- Hsiung CY, Leung SW, Wang CJ, et al. THA prognostic factors of lung cancer patients with brain metastasis treated with radiotherapy. Journal of Neuro-Oncology 1998;36:71-7
  • 17- Olak J, Ferguson MK. Surgical management of second primary and metastatic lung cancer. In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, Minna JD, eds. Lung cancer: Principles and practice. Philadelphia: Lippincott Williams & Wilkins, 2000:730-41
  • 18- Pachell RA. Treatment of brain metastasis. In: Pery MC. American Society of Clinical Oncology Educational Book, 2002: 83-91
  • 19- Ferrigno D, Buccheri G. Cranial computed tomography as a part of the initial staging procedures for patients with non-small-cell lung cancer. Chest 1994;106:1025-9
  • 20- Bonette P, Puyo P, Gabriel C, et al. Surgical management of non-small cell lung cancer with synchronous brain metastasis. Chest 2001;119:1469-75
  • 21- Spiro SG, Porter JC. Lung cancer-where are we today? Current advances in staging and nonsurgical treatment.Am J Respir Crit Care Med 2002;166:1166-96
  • 22- Yılmaz U, Ediboğlu H, Yasan H ve ark. Küçük hücreli dışı akciğer kanserinin başlangıç evrelemesinde bilgisayarlı beyin tomografisi. Solunum Hastalıkları 1998;9:443-51
  • 23- Rodrigus P, de Brouwer P, Raoymakers E. Brain metastasis and non-small cell lung cancer. Prognostic factors and correlation with survival after irradiation. Lung Cancer 2001;32:129-36
  • 24- Penel N, Birchet A, Prevost B, et al. Prognostic factors of synchronous brain metastasis from lung cancer. Lung Cancer 2001;33:143-54
  • 25- Lagerwaard FJ, Lavendag PC, Nowak PJ, et al. Identification of prognostic factors in patients with brain metastasis: A review of 1292 patients. Int J Radiat Oncol Biol Phys 1999;43:795-803
  • 26- Shadidi H, Kvale PA. Long-term survival following surgical treatment of solitary brain metastasis in non-smallcell lung cancer. Chest 1996;109:271-6
  • 27- Kelly K, Bunn Jr PA. Is it time to re evaluate our approach to the treatment of brain metastasis in patients with non-small cell lung cancerLung Cancer 1998;20:85-91
  • 28- Keime-Guibert F, Napolitano M, Delattre JY. Neurological complications of radiotherapy and chemotherapy. J Neurol 1998; 245:695-708
  • 29- Lee AW, Kwong DL, Leung SF, et al. Factors affecting risk of symptomatic temporal lobe necrosis: Significance of fractional dose and treatment time. Int J Radiat Oncol Biol Phys 2002, 53:75-85
Toplam 29 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Gürkan Berikol 0000-0001-6434-8143

Emel Avcı Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 7 Sayı: 1

Kaynak Göster

APA Berikol, G., & Avcı, E. (2021). Retrospective Examination of İntracranial Metastasis Tumors. Sanitas Magisterium, 7(1), 56-72.
AMA Berikol G, Avcı E. Retrospective Examination of İntracranial Metastasis Tumors. Sanitas magisterium. Ocak 2021;7(1):56-72.
Chicago Berikol, Gürkan, ve Emel Avcı. “Retrospective Examination of İntracranial Metastasis Tumors”. Sanitas Magisterium 7, sy. 1 (Ocak 2021): 56-72.
EndNote Berikol G, Avcı E (01 Ocak 2021) Retrospective Examination of İntracranial Metastasis Tumors. Sanitas Magisterium 7 1 56–72.
IEEE G. Berikol ve E. Avcı, “Retrospective Examination of İntracranial Metastasis Tumors”, Sanitas magisterium, c. 7, sy. 1, ss. 56–72, 2021.
ISNAD Berikol, Gürkan - Avcı, Emel. “Retrospective Examination of İntracranial Metastasis Tumors”. Sanitas Magisterium 7/1 (Ocak 2021), 56-72.
JAMA Berikol G, Avcı E. Retrospective Examination of İntracranial Metastasis Tumors. Sanitas magisterium. 2021;7:56–72.
MLA Berikol, Gürkan ve Emel Avcı. “Retrospective Examination of İntracranial Metastasis Tumors”. Sanitas Magisterium, c. 7, sy. 1, 2021, ss. 56-72.
Vancouver Berikol G, Avcı E. Retrospective Examination of İntracranial Metastasis Tumors. Sanitas magisterium. 2021;7(1):56-72.

https://dergipark.org.tr/tr/download/journal-file/2143321433