Toxicity and phytochemical analysis of petroleum-ether, ethanolic and aqueous extracts of Ceratotheca sesamoides

Yıl 2020, Cilt: 3 Sayı: 2, 148 - 155, 15.08.2020

Williams Chintem D.g. , İsmaila Yada Sudi , Manaseh Sılas

https://doi.org/10.38001/ijlsb.681349

Öz

This research investigated the toxicity and phytochemical analysis of aqueous ethanol and pet ether extract of Ceratotheca sesamoides leaves in albino wistar rats. Qualitative and quantitative phytochemical screening of Ceratotheca sesamoides were carried out. The result of the toxicity test revealed that aqueous extracts of Ceratotheca sesamoides leaf did not show any fatality with dosage range (300 mg-5000 mg). This shows that the LD50 is greater than 5000 mg/Kg body weight.The phytochemical investigation shows the presence of glycoside, carbohydrate and alkaloid in all the extract and only flavonoid was found in Aqueous and ethanol extracts. This shows that C. sesamoides is safe for consumption and is rich in polyphenols, flavonoids and tannins.

Anahtar Kelimeler

toxicity, phytochemical, fatality, Ceratotheca sesamoides

Kaynakça

• Fasakin, K. (1991). Studies on the effect of sowing depth and planting density on vegetative growth and leaf yield of two local cultivars of ceratotheca sesamoides Endl. M.Sc. Project, University of 11 or in, llorin. 128.
• Gbile, Z. O. (1983). Indigenous and adapted African vegetables. In 6th African symposium on Hort. Crops, Ibadan, Nigeria. Ed. Omidiji, M.O. Acta Horticulturae, 123, 76.
• Adegoke, E., Akinnsanya A. and Nagu, A. (1968). Studies of Nigerian medicinal plants. J West Afr Sci Ass.13: 13-39
• Obi, R.K., Iroagba, I.I. and Ojiako. O.A. (2006). Virucidal potential of some edible Nigerian vegetables. African Journal of Biotechnology. 5 (19): 1785-1788.
• Bakare, S.O., (1987). Effect of niUogen on yield of Ceratotheca sesamoides Endl. B. Agric. Project, Department of Crop Production, University of Ilorin, Ilorin, 87 p
• Anon, (2003). Medicinal plants. In: International Trade Forum- The Quarterly Magazine of the International Trade Centre. Retrieved from www, tradeforum.org. Grubben, G. J. H. and Denton, O. A. (2004). Plant Resources of Tropical Africa 2: Vegetables. PROTA Foundation, Netherlands/Beckluys Publishers, Wageningen. 63 - 176.
• Burkill, H.M. (1985).The Useful Plants of West Tropical Africa, Royal Botanic Gardens, 4. Yakubu, M. T., Opakunle, F. K., Salimon, S.S., Ajiboye, T. O., Bamisaye, F. A and Quadiri, A.L. (2012). Antidiarrhoeal activity of aqueous leaf extract of Ceratotheca sesamoides in rat. Journal of Bangladesh Pharmocological society.