Bazı Kronik Hastalıklarda Orta Zincirli Yağ Asitlerinin Kullanımı

Yıl 2018, Cilt: 3 Sayı: 3, 25 - 29, 05.10.2018

Aylin Bayındır Gümüş Hülya Yardımcı

Öz

Bazı Kronik Hastalıklarda Orta Zincirli Yağ Asitlerinin Kullanımı

 

Özet 

        Orta zincirli yağ asitleri 6-12 karbonlu yağ asitlerinden oluşur ve sindirimleri için pankreas enzimlerine ya da safra tuzlarına gereksinim duymazlar. İnce bağırsağa ulaştıklarında yağ asidi formunda olduklarından hemen karaciğere taşınır ve karaciğerde metabolize edilirler. Orta zincirli yağ asitlerinin sindirilmesindeki bu farklılık pek çok hastalığın tedavisine ışık tuttuğu için son derece önemlidir. Orta zincirli yağ asitleri son yıllarda epilepsi, obezite, anoreksiya nevroza, yağ metabolizması bozuklukları, inflamatuvar bağırsak hastalıkları ve tip 2 diyabet gibi bazı kronik hastalıkların tedavisinde alternatif tedavi olarak düşünülmektedir. Yapılan çalışmalarda orta zincirli yağ asitlerinden zengin diyetin keton cisimlerini arttırdığı, açlık ve tokluk metabolizmasında etkili olduğu, bağışıklık sistemini güçlendirdiği, insülin direncini düşürerek glukoz metabolizmasını etkilediği ve beyin fonksiyonlarında olumlu etkilerinin olduğu bulunmuştur. Ancak diğer yağ asitlerinden üstünlük sağlamadığı konusunda da bazı çalışmalar mevcuttur. Bu derlemede orta zincirli yağ asitlerinin bazı özellikleri ve kronik hastalıklarda kullanımı konusunda bilgi vermek amaçlanmıştır.

Anahtar
Kelimeler: (3-5 Kelime): Orta zincirli yağ asidi, beslenme, beslenme tedavisi, hastalıklar

 

Use of Medium Chain Fatty Acids in Diseases

 

Abstract (≤250 WORDS)

       Medium chain fatty acids are composed of 6-12 carbon fatty acids and do not require bile salts and pancreatic enzymes for digestion. When they reach the small intestine, they are immediately transported to the liver and metabolized in the liver because they are in the form of fatty acids. This difference in the digestibility of medium chain fatty acids is extremely important because it sheds light on the treatment of many diseases. In recent years, medium chain fatty acids have been considered as an alternative treatment for some chronic diseases such as epilepsy, obesity, anorexia nervosa, disorders of lipid metabolism, inflammatory bowel diseases and type 2 diabetes. Studies have shown that diet rich in medium chain fatty acids increase ketone bodies, are effective in hunger and satiety metabolism, boost immune system, affect glucose metabolism by reducing insulin resistance and have positive effects on brain functions. However there are some studies concluding they are not superior to other fatty acids. This review was written to provide information on some properties of medium chain fatty acids and their use in some chronic diseases

Keywords:
(3-5
Words): Medium chain triglyceride, nutrition, nutritional therapy, diseases.

Anahtar Kelimeler

Orta zincirli yağ asidi, beslenme, beslenme tedavisi

Kaynakça

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