Derleme
BibTex RIS Kaynak Göster

ANABOLİK ETKİYE SAHİP BESİN TAKVİYELERİ: POTANSİYEL MEKANİZMALAR VE KAS GELİŞİMİ

Yıl 2017, Cilt: 4 Sayı: 2, 48 - 56, 01.10.2017

Öz

Kuvvet antrenmanı yapanların temel amaçlarından biri kas
kütlesinde artış sağlamaktır. Düzenli olarak yapılan kuvvet antrenmanları, her
ay 0 ila 1 kg arasında yağsız vücut ağırlığında (YVA) artışa neden
olabilmektedir. Ancak bu gelişim tüm bireylerde aynı düzeyde
gerçekleşmemektedir. Bunun nedeni olarak, spor özgeçmişi, deneyim, beslenme ve
genetizm gibi faktörler gösterilmektedir. Bundan dolayı kuvvet egzersizi
yapanlar, YVA arttırmak için kuvvet antrenmanlarının yanında genellikle
besinsel takviyeler veya farmakolojik ajanları da kullanmaktadırlar. Kas
gelişimi (hipertrofi) ve kuvvet artırmada aminoasit ve protein sentezinin rolü
bilinmesine rağmen takviye olarak bu protein tozları ve aminoasitlerin
kullanımı hala tartışmalıdır. Günlük alınması gereken protein miktarından daha
fazla protein tüketmenin hem elit sporcular hem de rekreasyonel spor yapanlar
arasında oldukça yaygındır. Ancak, fazla tüketilen bu protein ve aminoasit
türevlerinin sportif performansı ve kas kütlesini arttırdığına dair çok az
bilimsel kanıt bulunmaktadır. Bundan dolayı bu derleme çalışmada, anabolik
etkiye sahip olan besin takviyelerin potansiyel etki mekanizmaları hakkında
kanıta dayalı açıklamalar yapmaya çalışılmıştır. 

Kaynakça

  • Erdman KA, Fung TS, Reimer RA. (2006). Influence of performance level on dietary supplementation in elite Canadian athletes. Med Sci Sports Exerc. 38, 349–56. Lieberman HR, Stavinoha TB, Mcgraw SM, et al. (2010). Use of dietary supplements among active-duty U.S. Army soldiers. Am J Clin Nutr. 92, 985–95. Petroczi A, Naughton CP. (2008).The age-gender-status profile of high performing athletes in the UK taking nutritional supplements: Lessons for the future. J Int Soc Sports Nutr. 5:2. Pasiakos SM, Montain SJ, Young AJ. (2013).Protein supplementation in U.S. Military personnel. J Nutr.143, 1815–9. Erdman KA, Fung TS, Doyle-Baker PK, et al. (2007). Dietary supplementation of high-performance Canadian athletes by age and gender. Clin J Sport Med. 17, 458–64. Lemon PW. (2000) Beyond the zone: protein needs of active individuals. J Am Coll Nutr. 19, (5 Suppl.): 513-21 Williams MH. (1999). Facts and fallacies of purported ergogenic amino acid supplements. Clin Sports Med.18 (3). 633-49 Tarnopolsky MA, Atkinson SA, MacDougall JD, et al. (1992). Evaluation of protein requirements for trained strength athletes. J Appl Physiol. 73 (5): 1986-95. Pasiakos, S. M., McLellan, T. M., & Lieberman, H. R. (2015). The effects of protein supplements on muscle mass, strength, and aerobic and anaerobic power in healthy adults: a systematic review. Sports medicine, 45(1), 111-131. Campbell, B. I. (2011). NSCA s Guide to Sport and Exercise Nutrition. Human Kinetics. Campbell B, Kreider RB, Ziegenfuss T, et al. (2007). International society of sports nutrition position stand: protein and exercise. J Int Soc Sports Nutr.4:8. Rodriguez NR, DiMarco NM, Langley S. (2009). Nutrition and athletic performance. Joint position statement for the American Dietetic Association, Dietiticians of Canada and the American College of Sports Medicine. Med Sci Sports Exerc. 41, 709–31. Chesley, A., MacDougall, J. D., Tarnopolsky, M. A., Atkinson, S. A., and Smith, K. , (1992).Changes in human muscle protein synthesis after resistance exercise, J. Appl. Physiol., 73, 1383 Marable, N. L., Hickson, J. F., Korslund, M. K., Herbert, W. G., Desjardins, R. F., and Thye, F. W., (1979). Urinary nitrogen excretion as influence by a muscle building exercise program and protein intake variation, Nutr. Rep. Int., 19, 795, Yarasheski, K. E., Zachwieja, J. J., Angelopoulos, T. J., and Bier, D. M.,(1993).Short-term growth hormone treatment does not increase muscle protein synthesis in experienced weightlifters, J. Appl. Physiol., 74, 3073, Elam, R. P., Hardin, D. H., Sutton, R. A. L., and Hagen, L., (1989). Effects of arginine and ornithine on strength, lean body mass and urinary hydroxyproline in adult males, J. Sports Med. Phys. Fit., 29, 52, Kraemer WJ. (1994). General adaptations to resistance and endurance training. In: Baechle T, editor. Essentials of strength training and conditioning. Champaign (IL): Human Kinetics,127-50. Forbes GB.( 1991).Exercise and body composition. J Appl Physiol. 70: 994-7. Wilmore JH. (1974). Alterations in strength, body composition, and anthropometric measurements consequent to a 10 week weight training program. Med Sci Sport Exerc 6: 133-8. Hider, R. C., E. B. Fern, and D. R. London. (1960). Relationship between intracellular amino acids and protein synthesis in the extensor digitorum longus muscle of rats. Biochem. J. 114: 171–178. Børsheim, E., Tipton, K. D., Wolf, S. E., & Wolfe, R. R. (2002). Essential amino acids and muscle protein recovery from resistance exercise. American Journal of Physiology-Endocrinology And Metabolism, 283(4), 648-657. Biolo G, Tipton KD, Klein S, and Wolfe RR. (1997). An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol Endocrinol Metab 273: 122– 129,. Tipton KD, Ferrando AA, Phillips SM, Doyle D Jr, and Wolfe RR. (1999). Post exercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol Endocrinol Metab 276: 628–634,. Wernbom M, Augustsson J, Thomee R (2007) The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans. Sports Med 37: 225–264 Benardot, D. (2006). Advanced sports nutritions. (Vol.11). Champaign, III, USA: Human kinetics, Nagle, EJ., and Bassett, D.R. (1989). Energ):' metabolism. In Nutrition in exercise and sport, ed. Hickson, J .E, and Wolinsky, I. Boca Raton, FL: CRC Press, 87-106. Greenhaff, P.L. (1995). Creatine and its application as an ergogenic aid. Int.]. Sport Nutr. 5: 1-11 O.Greenhaff, P.L., Casey, A., Shon, A.H., Harris, R, Soderlund, K, and Hultman, E. (1993). Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin. Sci. 84: 565-571. Maughan, R.J. (1995). Creatine supplementation and exercise performance. Inti. ]. Sport Nutr. 5: 94-101. VolekJS and Rawson ES. (2004) Scientific basis and practical aspects of creatine supplementation for athletes. Nutrition.20: 609-614. Kozak, C.]., Benardot, D., Cody, M., Doyle, J.A., and Thompson, W:R (1996). The effect of creatine monohydrate supplementation on anaerobic power and anaerobic endurance in elite female gymnasts. Master's thesis, Georgia State University. Koenig C, Benardot 0, Cody M, and Thompson (2004). The influence of creatine monohydrate and carbohydrate supplements on repeated jump height. Medicine and Science in Sports and Exercise 36(5): 347. Maughan, RJ. (1995). Creatine supplementation and exercise performance. Inti.]. Sport Nutr. 5: 94-101. Walker,J.B. (1979). Creatine biosynthesis, regulation, and function. Adv. Enzmmol. 50: 117-142. Lemon, P.W. and Proctor, D.N. (1991). Protein intake and athletic performance. Sports Medicine, 12, 313-325. Dangin M, Guillet C, Garcia-Rodenas C, et al. (2003) The rate of protein digestion affects protein gain differently during aging in humans. J Physiol. 549: 635–644. Paddon-Jones D, Sheffield-Moore M, Katsanos CS, et al. (2006) Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol. 41: 215–219. Paddon-Jones D, Sheffield-Moore M, Aarsland A, et al. (2005). Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am J Physiol Endocrinol Metab. 288: 761–767. Paddon-Jones D, Sheffield-MooreM, Urban RJ, et al. (2004). Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab.89: 4351–4358. Burke DG, Chilibeck PD, Davidson KS, et al. (2001). The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength. Int J Sport Nutr Exerc Metab. 11: 349–364. Cribb PJ, Williams AD, Hayes A, Carey MF. (2006). The effect of whey isolate on strength, body composition and plasma glutamine. Int J Sports Nutr Exerc Metab. 16: 494–509. Cribb PJ, Williams AD, Hayes A. A(2007). creatine–protein–carbohydrate supplement enhances responses to resistance training. Med Sci Sports Exerc Cribb PJ, Williams AD, Stathis CG, et al. (2007). Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc 39: 298–307. Hayes, A., & Cribb, P. J. (2008). Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training. Current Opinion in Clinical Nutrition & Metabolic Care, 11(1), 40-44. Tipton KD, Borsheim E, Wolf S, et al. (2003). Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab. 284: 76–89. Tipton KD, Elliott TA, Cree MG, et al. (2004)Ingestion of casein and whey proteins result in muscle anabolism after resistance exercise. Med Sci Sports Exerc. 36: 2073–2081. Cribb PJ.( 2005).Whey proteins in sports nutrition. Arlington: US Dairy Export Council; Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr 2006; 136: 533–537. Layman DK, Walker DA. (2006) Potential importance of leucine in treatment of obesity and the metabolic syndrome. J Nutr.136: 319–323. Farnfield MM, Carey KA, Cameron-Smith D. (2005). Whey protein supplementation and resistance training to enhance muscle growth in young and older adults. Asia Pac J Clin Nutr. 14 (Suppl):S69. Rennie MJ. (1996) Glutamine metabolism and transport in skeletal muscle and heart and their clinical relevance. J Nutr. 126 (4 Suppl.): 1142-9. Rennie MJ, Tadros L, Khogali S, et al. (1994). Glutamine transport and its metabolic effects. J Nutr. 124 (8 Suppl.): 1503-8. Low SY, Taylor PM, Rennie MJ. (1996). Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume. J Physiol (Lond). 492 (Pt 3): 877-85 Varnier M, Leese GP, Thompson J, et al. (1995). Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am J Physiol 269 (2 Pt 1): 309-15. Parry-Billings M, Budgett R, Koutedakis K, et al. (1992). Plasma amino acid concentrations in the overtraining syndrome: possible effects on the immune system. Med Sci Sport Exerc. 24: 1353-8 Kargotich S, Rowbottom DG, Keast D, et al. (1996). Plasma glutamine changes after high intensity exercise in elite male swimmers [abstract]. Med Sci Sport Exerc 28: 133 Kreider RB. (1998). Central fatigue hypothesis and overtraining. In: Kreider RB, Fry AC, O’Toole ML, editors. Overtraining in sport. Champaign (IL): Human Kinetics, 309-31. Zuhl MN, Lanphere KR, Kravitz L, Mermier CM, Schneider S, Dokladny K, Moseley PL. (2014). Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression. J Appl Physiol. 116: 183–191. Dokladny K, Zuhl MN, Mandell M, Bhattacharya D, Schneider S, Deretic V, Moseley PL. (2013). Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. J Biol Chem. 288: 14959–14972. Castell L.( 2003). Glutamine supplementation in vitro and in vivo, in exercise and in immunodepression. Sports Med.33: 323–345. Cruzat VF, Rogero MM, Tirapegui J. (2010). Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise. Cell Biochem Funct. 28: 24–30. Lambert GP, Broussard LJ, Mason BL, Mauermann WJ, Gisolfi CV. (2001). Gastrointestinal permeability during exercise: effects of aspirin and energy-containing beverages. J Appl Physiol. 90(1985): 2075–2080. Carr EL, et al.( 2010). Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J Immunol. 185: 1037–1044. Legault, Z., Bagnall, N., & Kimmerly, D. S. (2015). The influence of oral L-glutamine supplementation on muscle strength recovery and soreness following unilateral knee extension eccentric exercise. International journal of sport nutrition and exercise metabolism, 25(5), 417-426. Zuhl, M., Dokladny, K., Mermier, C., Schneider, S., Salgado, R., & Moseley, P. (2015). The effects of acute oral glutamine supplementation on exercise-induced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells. Cell Stress and Chaperones, 20(1), 85-93. Phillips SM, Tipton KD, Aarsland A,Wolf SE,Wolfe RR. (1997). Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol. 273: 99–107. Miller SL, Tipton KD, Chinkes DL, Wolf SE, Wolfe RR. (2003). Independent and combined effects of amino acids and glucose after resistance exercise. Med Sci Sports Exerc. 35: 449–55. Beelen M, Koopman R, Gijsen AP, et al. (2008). Protein coingestion stimulates muscle protein synthesis during resistance-type exercise. Am J Physiol Endocrinol Metab. 295: 70–7. Levenhagen DK, Gresham JD, Carlson MG, Maron DJ, Borel MJ, Flakoll PJ. (2001). Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis. Am J Physiol Endocrinol Metab. 280: 982–93. Tipton KD, Rasmussen BB, Miller SL, et al. (2001). Timing of amino acidcarbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab. 281: 197–206. Nair KS, Schwartz RG, Welle S. (1992). Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Am J Physiol. 263 (5 Pt 1): 928-34 Nissen S, Sharp R, Ray M, et al. (1996). Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training. J Appl Physiol. 81: 2095-104 Green, A.L., Hultman, E., Macdonald, I.A., Sewell, D.A., Greenhaff, P.L. (1996) Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol, 27(5): 821-6 Steenge, G.R., Lambourne, J., Casey, A., Macdonald, I.A., Greenhaff, P.L. (1998) Stimulatory effect of insulin on creatine accumulation in human skeletal muscle. Am J Physiol, 275(6): 974-9
Yıl 2017, Cilt: 4 Sayı: 2, 48 - 56, 01.10.2017

Öz

Kaynakça

  • Erdman KA, Fung TS, Reimer RA. (2006). Influence of performance level on dietary supplementation in elite Canadian athletes. Med Sci Sports Exerc. 38, 349–56. Lieberman HR, Stavinoha TB, Mcgraw SM, et al. (2010). Use of dietary supplements among active-duty U.S. Army soldiers. Am J Clin Nutr. 92, 985–95. Petroczi A, Naughton CP. (2008).The age-gender-status profile of high performing athletes in the UK taking nutritional supplements: Lessons for the future. J Int Soc Sports Nutr. 5:2. Pasiakos SM, Montain SJ, Young AJ. (2013).Protein supplementation in U.S. Military personnel. J Nutr.143, 1815–9. Erdman KA, Fung TS, Doyle-Baker PK, et al. (2007). Dietary supplementation of high-performance Canadian athletes by age and gender. Clin J Sport Med. 17, 458–64. Lemon PW. (2000) Beyond the zone: protein needs of active individuals. J Am Coll Nutr. 19, (5 Suppl.): 513-21 Williams MH. (1999). Facts and fallacies of purported ergogenic amino acid supplements. Clin Sports Med.18 (3). 633-49 Tarnopolsky MA, Atkinson SA, MacDougall JD, et al. (1992). Evaluation of protein requirements for trained strength athletes. J Appl Physiol. 73 (5): 1986-95. Pasiakos, S. M., McLellan, T. M., & Lieberman, H. R. (2015). The effects of protein supplements on muscle mass, strength, and aerobic and anaerobic power in healthy adults: a systematic review. Sports medicine, 45(1), 111-131. Campbell, B. I. (2011). NSCA s Guide to Sport and Exercise Nutrition. Human Kinetics. Campbell B, Kreider RB, Ziegenfuss T, et al. (2007). International society of sports nutrition position stand: protein and exercise. J Int Soc Sports Nutr.4:8. Rodriguez NR, DiMarco NM, Langley S. (2009). Nutrition and athletic performance. Joint position statement for the American Dietetic Association, Dietiticians of Canada and the American College of Sports Medicine. Med Sci Sports Exerc. 41, 709–31. Chesley, A., MacDougall, J. D., Tarnopolsky, M. A., Atkinson, S. A., and Smith, K. , (1992).Changes in human muscle protein synthesis after resistance exercise, J. Appl. Physiol., 73, 1383 Marable, N. L., Hickson, J. F., Korslund, M. K., Herbert, W. G., Desjardins, R. F., and Thye, F. W., (1979). Urinary nitrogen excretion as influence by a muscle building exercise program and protein intake variation, Nutr. Rep. Int., 19, 795, Yarasheski, K. E., Zachwieja, J. J., Angelopoulos, T. J., and Bier, D. M.,(1993).Short-term growth hormone treatment does not increase muscle protein synthesis in experienced weightlifters, J. Appl. Physiol., 74, 3073, Elam, R. P., Hardin, D. H., Sutton, R. A. L., and Hagen, L., (1989). Effects of arginine and ornithine on strength, lean body mass and urinary hydroxyproline in adult males, J. Sports Med. Phys. Fit., 29, 52, Kraemer WJ. (1994). General adaptations to resistance and endurance training. In: Baechle T, editor. Essentials of strength training and conditioning. Champaign (IL): Human Kinetics,127-50. Forbes GB.( 1991).Exercise and body composition. J Appl Physiol. 70: 994-7. Wilmore JH. (1974). Alterations in strength, body composition, and anthropometric measurements consequent to a 10 week weight training program. Med Sci Sport Exerc 6: 133-8. Hider, R. C., E. B. Fern, and D. R. London. (1960). Relationship between intracellular amino acids and protein synthesis in the extensor digitorum longus muscle of rats. Biochem. J. 114: 171–178. Børsheim, E., Tipton, K. D., Wolf, S. E., & Wolfe, R. R. (2002). Essential amino acids and muscle protein recovery from resistance exercise. American Journal of Physiology-Endocrinology And Metabolism, 283(4), 648-657. Biolo G, Tipton KD, Klein S, and Wolfe RR. (1997). An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol Endocrinol Metab 273: 122– 129,. Tipton KD, Ferrando AA, Phillips SM, Doyle D Jr, and Wolfe RR. (1999). Post exercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol Endocrinol Metab 276: 628–634,. Wernbom M, Augustsson J, Thomee R (2007) The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans. Sports Med 37: 225–264 Benardot, D. (2006). Advanced sports nutritions. (Vol.11). Champaign, III, USA: Human kinetics, Nagle, EJ., and Bassett, D.R. (1989). Energ):' metabolism. In Nutrition in exercise and sport, ed. Hickson, J .E, and Wolinsky, I. Boca Raton, FL: CRC Press, 87-106. Greenhaff, P.L. (1995). Creatine and its application as an ergogenic aid. Int.]. Sport Nutr. 5: 1-11 O.Greenhaff, P.L., Casey, A., Shon, A.H., Harris, R, Soderlund, K, and Hultman, E. (1993). Influence of oral creatine supplementation on muscle torque during repeated bouts of maximal voluntary exercise in man. Clin. Sci. 84: 565-571. Maughan, R.J. (1995). Creatine supplementation and exercise performance. Inti. ]. Sport Nutr. 5: 94-101. VolekJS and Rawson ES. (2004) Scientific basis and practical aspects of creatine supplementation for athletes. Nutrition.20: 609-614. Kozak, C.]., Benardot, D., Cody, M., Doyle, J.A., and Thompson, W:R (1996). The effect of creatine monohydrate supplementation on anaerobic power and anaerobic endurance in elite female gymnasts. Master's thesis, Georgia State University. Koenig C, Benardot 0, Cody M, and Thompson (2004). The influence of creatine monohydrate and carbohydrate supplements on repeated jump height. Medicine and Science in Sports and Exercise 36(5): 347. Maughan, RJ. (1995). Creatine supplementation and exercise performance. Inti.]. Sport Nutr. 5: 94-101. Walker,J.B. (1979). Creatine biosynthesis, regulation, and function. Adv. Enzmmol. 50: 117-142. Lemon, P.W. and Proctor, D.N. (1991). Protein intake and athletic performance. Sports Medicine, 12, 313-325. Dangin M, Guillet C, Garcia-Rodenas C, et al. (2003) The rate of protein digestion affects protein gain differently during aging in humans. J Physiol. 549: 635–644. Paddon-Jones D, Sheffield-Moore M, Katsanos CS, et al. (2006) Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol. 41: 215–219. Paddon-Jones D, Sheffield-Moore M, Aarsland A, et al. (2005). Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am J Physiol Endocrinol Metab. 288: 761–767. Paddon-Jones D, Sheffield-MooreM, Urban RJ, et al. (2004). Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab.89: 4351–4358. Burke DG, Chilibeck PD, Davidson KS, et al. (2001). The effect of whey protein supplementation with and without creatine monohydrate combined with resistance training on lean tissue mass and muscle strength. Int J Sport Nutr Exerc Metab. 11: 349–364. Cribb PJ, Williams AD, Hayes A, Carey MF. (2006). The effect of whey isolate on strength, body composition and plasma glutamine. Int J Sports Nutr Exerc Metab. 16: 494–509. Cribb PJ, Williams AD, Hayes A. A(2007). creatine–protein–carbohydrate supplement enhances responses to resistance training. Med Sci Sports Exerc Cribb PJ, Williams AD, Stathis CG, et al. (2007). Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc 39: 298–307. Hayes, A., & Cribb, P. J. (2008). Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training. Current Opinion in Clinical Nutrition & Metabolic Care, 11(1), 40-44. Tipton KD, Borsheim E, Wolf S, et al. (2003). Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab. 284: 76–89. Tipton KD, Elliott TA, Cree MG, et al. (2004)Ingestion of casein and whey proteins result in muscle anabolism after resistance exercise. Med Sci Sports Exerc. 36: 2073–2081. Cribb PJ.( 2005).Whey proteins in sports nutrition. Arlington: US Dairy Export Council; Norton LE, Layman DK. Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise. J Nutr 2006; 136: 533–537. Layman DK, Walker DA. (2006) Potential importance of leucine in treatment of obesity and the metabolic syndrome. J Nutr.136: 319–323. Farnfield MM, Carey KA, Cameron-Smith D. (2005). Whey protein supplementation and resistance training to enhance muscle growth in young and older adults. Asia Pac J Clin Nutr. 14 (Suppl):S69. Rennie MJ. (1996) Glutamine metabolism and transport in skeletal muscle and heart and their clinical relevance. J Nutr. 126 (4 Suppl.): 1142-9. Rennie MJ, Tadros L, Khogali S, et al. (1994). Glutamine transport and its metabolic effects. J Nutr. 124 (8 Suppl.): 1503-8. Low SY, Taylor PM, Rennie MJ. (1996). Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume. J Physiol (Lond). 492 (Pt 3): 877-85 Varnier M, Leese GP, Thompson J, et al. (1995). Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am J Physiol 269 (2 Pt 1): 309-15. Parry-Billings M, Budgett R, Koutedakis K, et al. (1992). Plasma amino acid concentrations in the overtraining syndrome: possible effects on the immune system. Med Sci Sport Exerc. 24: 1353-8 Kargotich S, Rowbottom DG, Keast D, et al. (1996). Plasma glutamine changes after high intensity exercise in elite male swimmers [abstract]. Med Sci Sport Exerc 28: 133 Kreider RB. (1998). Central fatigue hypothesis and overtraining. In: Kreider RB, Fry AC, O’Toole ML, editors. Overtraining in sport. Champaign (IL): Human Kinetics, 309-31. Zuhl MN, Lanphere KR, Kravitz L, Mermier CM, Schneider S, Dokladny K, Moseley PL. (2014). Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression. J Appl Physiol. 116: 183–191. Dokladny K, Zuhl MN, Mandell M, Bhattacharya D, Schneider S, Deretic V, Moseley PL. (2013). Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. J Biol Chem. 288: 14959–14972. Castell L.( 2003). Glutamine supplementation in vitro and in vivo, in exercise and in immunodepression. Sports Med.33: 323–345. Cruzat VF, Rogero MM, Tirapegui J. (2010). Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise. Cell Biochem Funct. 28: 24–30. Lambert GP, Broussard LJ, Mason BL, Mauermann WJ, Gisolfi CV. (2001). Gastrointestinal permeability during exercise: effects of aspirin and energy-containing beverages. J Appl Physiol. 90(1985): 2075–2080. Carr EL, et al.( 2010). Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J Immunol. 185: 1037–1044. Legault, Z., Bagnall, N., & Kimmerly, D. S. (2015). The influence of oral L-glutamine supplementation on muscle strength recovery and soreness following unilateral knee extension eccentric exercise. International journal of sport nutrition and exercise metabolism, 25(5), 417-426. Zuhl, M., Dokladny, K., Mermier, C., Schneider, S., Salgado, R., & Moseley, P. (2015). The effects of acute oral glutamine supplementation on exercise-induced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells. Cell Stress and Chaperones, 20(1), 85-93. Phillips SM, Tipton KD, Aarsland A,Wolf SE,Wolfe RR. (1997). Mixed muscle protein synthesis and breakdown after resistance exercise in humans. Am J Physiol. 273: 99–107. Miller SL, Tipton KD, Chinkes DL, Wolf SE, Wolfe RR. (2003). Independent and combined effects of amino acids and glucose after resistance exercise. Med Sci Sports Exerc. 35: 449–55. Beelen M, Koopman R, Gijsen AP, et al. (2008). Protein coingestion stimulates muscle protein synthesis during resistance-type exercise. Am J Physiol Endocrinol Metab. 295: 70–7. Levenhagen DK, Gresham JD, Carlson MG, Maron DJ, Borel MJ, Flakoll PJ. (2001). Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis. Am J Physiol Endocrinol Metab. 280: 982–93. Tipton KD, Rasmussen BB, Miller SL, et al. (2001). Timing of amino acidcarbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab. 281: 197–206. Nair KS, Schwartz RG, Welle S. (1992). Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Am J Physiol. 263 (5 Pt 1): 928-34 Nissen S, Sharp R, Ray M, et al. (1996). Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training. J Appl Physiol. 81: 2095-104 Green, A.L., Hultman, E., Macdonald, I.A., Sewell, D.A., Greenhaff, P.L. (1996) Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol, 27(5): 821-6 Steenge, G.R., Lambourne, J., Casey, A., Macdonald, I.A., Greenhaff, P.L. (1998) Stimulatory effect of insulin on creatine accumulation in human skeletal muscle. Am J Physiol, 275(6): 974-9
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Konular Spor Hekimliği
Bölüm Hareket ve Egzersiz Bilimi
Yazarlar

Muhammed Emin Kafkas

Emrah Demirtaş Bu kişi benim

Armağan Kafkas

Yayımlanma Tarihi 1 Ekim 2017
Gönderilme Tarihi 6 Kasım 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 4 Sayı: 2

Kaynak Göster

APA Kafkas, M. E., Demirtaş, E., & Kafkas, A. (2017). ANABOLİK ETKİYE SAHİP BESİN TAKVİYELERİ: POTANSİYEL MEKANİZMALAR VE KAS GELİŞİMİ. İnönü Üniversitesi Beden Eğitimi Ve Spor Bilimleri Dergisi, 4(2), 48-56.

------------------------------------------------------------------------------------------------------------------------------