Sperm Morfolojisi ve Kromatin Kondensasyon Defektleri Arasındaki Korelasyon

Yıl 2008, Cilt: 39 Sayı: 4, 128 - 135, 20.07.2014

Sevilay Erimşah İsmail Seçkin Seyfettin Uludağ Tülay İrez

Anahtar Kelimeler

Spermatozoa, kromatin morfolojik anormallikler, elektron mikroskobu, erkek infertilitesi

Kaynakça

• 1. Hofmann N, Hilscher B. Use of aniline blue to assess chromatin condensation in morphologically normal spermatozoa in normal and infertile men. Hum Reprod 1991; 6: 979-982.
• 2. Vincent W. Aoki, Douglas T. Carrell . Human protamines and the developing spermatid:their structure, function, expression and relationship with male infertility. Asian J Androl 2003; 5: 315-324.
• 3. Foresta C, Zorzi M, Rossato M, Varotto A. Sperm nuclear instability and staining with aniline blue: abnormal persistence of histones in spermatozoa in infertile men. Int J Androl 1992; 15: 330-337
• 4. Sakkas D, Moffatt O, Manicardi GC, Mariethoz E, Tarozzi T, Bizzaro D. Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biology of reproduction 2002; 66: 1061-1067.
• 5. Sakkas D, Mariethoz E, Manicardi G, Bizzaro D, Bianchi PG, Bianchi U, Origin of DNA damage in ejaculated human spermatozoa. Reviews of Reproduction 1999; 4: 31-37.
• 6. Liu DY, Baker HW. Relationships between human sperm acrosin, acrosomes, morphology and fertilization in vitro. Hum Reprod 1990; 5: 298-303.
• 7. Bostofte E, Serup J, Rebbe H. Relation between morphologically abnormal spermatozoa and pregnancies obtained during a twenty-year follow-up period. Int J Androl 1982; 5(4): 379-86.
• 8. Evenson DP, Darzynkiewicz Z, Melamed MR. Relation of mammalian sperm chromatin heterogeneity to fertility. Science 1980; 210: 1131-1133.
• 9. Alexandre C, Bisson JP, David G. Total asthenospermia with an ultrastructural anomaly of the flagellum in two sterile brothers (author's transl) J Gynecol Obstet Biol Reprod 1978; 7: 31-38.
• 10. Dozortsev D, Rybouchkin A, De Sutter P, Qian C, Dhont M. Human oocyte activation following intracytoplasmic injection: the role of the sperm cell. Hum Reprod 1995; 10: 403-407.
• 11. Jack, A.H. and Hrudka, F. Patterns and dynamics of teratospermia induced in rams by parenteral treatment with ethylene dibromide. J Androl 1996; 16: 194-211.
• 12. Chemes, H., Fawcett, D.W. and Dym, M. Unusual features of the nuclear envelope in human spermatogenic cells. Anat Rec 1979; 192: 493-523.
• 13. Zamboni, L. Sperm structure and its relevance to infertility. An electron microscopic study. Arch Pathol Lab Med 1992; 116: 325-344.
• 14. Baccetti, B., Burrini, A.G., Collodel, G., Piomboni, P. and Renieri T.A “miniacrosome” sperm defect causing infertility in two brothers. J Androl 1991; 12: 104- 111.
• 15. Liu, D.Y. and Baker, H.W. Disordered acrosome reaction of spermatozoa bound to the zona pellucida: a newly discovered sperm defect causing infertility with reduced sperm±zona pellucida penetration and reduced fertilization in vitro. Hum Reprod 1994; 9: 1694-1700.
• 16. Kalahanis, J., Rousso, D., Kourtis, A., Mavromatidis, G., Makedos, G. and Panidis, D. Round-headed spermatozoa in semen specimens from fertile and subfertile men. J Reprod Med 2002; 47: 489-493.
• 17. Zamboni, L. The ultrastructural pathology of the spermatozoon as a cause of infertility: the role of electron microscopy in the evaluation of semen quality. Fertil Steril 1987; 48: 711-734.