Araştırma Makalesi

DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR

Cilt: 13 Sayı: 2 25 Aralık 2013
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DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR

Öz

Microcantilevers are one of the basic micromechanical structures. They are fixed at one ends and the other ends can move freely like a diving board. Their sizes are in the micrometer and nanometer ranges. Microcantilevers are called microcantilever sensors when their surfaces are functionalized to detect specific molecules. Since these sensors have offered remarkable possibilities in detection, they have been used in many fields such as clinical diagnosis, drug screening and pathogen detection. In the microcantilever sensors, various detection methods are available such as piezoresistive, optical, capacitive and piezoelectric. Each sensing method holds own advantages and disadvantages. By the advantage of allowing integration of the read-out electronics on the same chip, piezoresistive detection becomes prominent. So piezoresistive detection is chosen in this work and a basic piezoresistive microcantilever biosensor design is introduced. Furthermore, by making geometrical alterations on microcantilever and piezoresistive layer, effects of these variations upon sensitivity, vertical displacement and change in resistance are investigated. Additionally, effects of different shaped holes upon sensor are studied.

Anahtar Kelimeler

Kaynakça

  1. Hansen, K. M., Thundat, T., “Microcantilever biosensors”, Methods, Vol: 37, No: 1, pp. 57-64, 2005.
  2. Frometa, N. R., “Cantilever biosensors”, Biotecnologia Aplicada, Vol: 23, No: 4, pp. 320-323, 2006.
  3. Bais, B., Rahim, R. A., Majlis, B. Y., “Finite element and system level analyses of piezoresistive microcantilever for biosensing applications”, Australian Journal of Basic & Applied Sciences, Vol: 5, No: 12, pp. 1038-1046, 20 Lim, Y. C., Kouzani, A. Z., Duan, W., Kaynak, A., “Effects of design parameters on sensivity of microcantiilever biosensors”, IEEE International Conference on Complex Medical Engineering-ICME, 2010.
  4. Alvarez, M., Lechuga, L. M., “Microcantilever-based platforms as biosensing tools”, Analyst, Vol: 135, No: 5, pp. 827-836, 2010.
  5. Ziegler, C., “Cantilever based biosensors”, Analytical & Bioanalytical Chemistry. Vol: 379, No: 7/8, pp. 946-959, 200 Villanueva, G., Rius, G., Montserrat, J., Murano, F. P., Bausells, J., “Piezoresistive microcantilevers for biomolecular force detection”, SCED, Spanish Conference on Electron Devices IEEE, 2007.
  6. He, J. H., Li, Y. F., ”High sensivity piezoresistive cantilever sensor for biomolecular detection” , Journal of Physics: Conference Series, Vol: 34, pp. 429-435, 2006.
  7. Johnson, B. N., Mutharasan, R., “Biosensing using dynamic - mode cantilever sensors: A review”, Biosensors and Bioelectronics , Vol: 32, No: 1, pp. 1-18, 2011.
  8. Datar, R., Kim, S., Jeon, S., Hesketh, P., Manalis, S., Boisen, A., Thundat, T., “Cantilever sensors: Nanomechanical tools for diagnostics”, MRS Bulletin, Vol: 34, No: 6, pp449-454, 2009.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Mühendislik

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

25 Aralık 2013

Gönderilme Tarihi

25 Aralık 2013

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2013 Cilt: 13 Sayı: 2

Kaynak Göster

APA
Sacu, İ., & Alcı, M. (2013). DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering, 13(2), 1641-1645. https://izlik.org/JA55KX34CW
AMA
1.Sacu İ, Alcı M. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering. 2013;13(2):1641-1645. https://izlik.org/JA55KX34CW
Chicago
Sacu, İbrahim, ve Mustafa Alcı. 2013. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering 13 (2): 1641-45. https://izlik.org/JA55KX34CW.
EndNote
Sacu İ, Alcı M (01 Aralık 2013) DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering 13 2 1641–1645.
IEEE
[1]İ. Sacu ve M. Alcı, “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”, IU-Journal of Electrical & Electronics Engineering, c. 13, sy 2, ss. 1641–1645, Ara. 2013, [çevrimiçi]. Erişim adresi: https://izlik.org/JA55KX34CW
ISNAD
Sacu, İbrahim - Alcı, Mustafa. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering 13/2 (01 Aralık 2013): 1641-1645. https://izlik.org/JA55KX34CW.
JAMA
1.Sacu İ, Alcı M. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering. 2013;13:1641–1645.
MLA
Sacu, İbrahim, ve Mustafa Alcı. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering, c. 13, sy 2, Aralık 2013, ss. 1641-5, https://izlik.org/JA55KX34CW.
Vancouver
1.İbrahim Sacu, Mustafa Alcı. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering [Internet]. 01 Aralık 2013;13(2):1641-5. Erişim adresi: https://izlik.org/JA55KX34CW