Dose and Time Controlled Electronic Insulin Pen: Bilensulin

Yıl 2017, Cilt: 17 Sayı: 1, 3083 - 3089, 27.03.2017

Mana Sezdı , Ahmet Bilen

Öz

In this
study, an electronic insulin pen was designed for diabetic patients dependent
on insulin use in order to prevent wrong timing and wrong dosage caused from
old age, vision or mental illness. During design, the patients’ necessities
such as easy-to-use, have been considered. The insulin pen that can be used
electronically for routine dose injections, and that is called as Bilensülin,
was designed to be able to used manually in the emergency. It is aimed that the
patient can set the dose easily by using the fairly simple menu of the device.
Additionally, the device was designed as reusable by changing the insulin
cartridge. Because the tube chamber was designed to be suitable for all types
of insulin, it can be used by changing cartridge without using different pen.
Dose accuracy was tested by performing insulin dose measurements on a sensitive
balance, and dose of Bilensulin was compared with the three types of insulin
pens.The patent has been applied for this designed electronic insulin pen. The
mechanism of change of cartridge has been put into the foreground in terms of
ease of use and constituted the sub-structure of the patent application.  Currently, the studies on the device are
continuing.

Anahtar Kelimeler

Insulin, dose, diabetes, insulin pen

Kaynakça

• [1] P. Sonksen, J. Sonksen, "Insulin: understanding its action in health and disease", Br J Anaesth, vol. 85, no. 1, pp. 69-79, July, 2000.
• [2] M. P. Baruah, "Insulin pens: the modern delivery devices", J Assoc Physicians India, vol. 59, pp. 38-40, Apr, 2011.
• [3] D. K. Dang, J. Lee, "Analysis of symposium articles on insulin pen devices and alternative insulin delivery methods", J Diabetes Sci Technol., vol. 4, no. 3, pp. 558-561, May, 2010.
• [4] S. L. Schwartz, D. A. Ignaut, J. N. Bodie, "Humalog KwikPen: an insulin-injecting pen designed for ease of use", Expert Rev Med Devices, vol. 7, no. 6, pp. 735-743, Nov, 2010.
• [5] E. K. McCoy, B. M. Wright, "A review of insulin pen devices", Postgraduate Medicine, vol. 122, no. 3, pp. 81-88, May, 2010.
• [6] G. Spollett, "Insulin devices: addressing barriers to insulin therapy with the ideal pen", Diabetes Educator, vol. 34, no. 6, pp. 957-960, 963,967, Nov, 2008.
• [7] D. A. Ignaut, M. R. Opincar, P. E. Clark, M. K. Palaisa, S. M. Lenox, "Engineering study comparing injection force and dose accuracy between two prefilled insulin injection pens", Curr Med Res Opin, vol. 25, no. 12, pp. 2829-2833, Dec, 2009.
• [8] T. L. Pearson, "Practical aspects of insulin pen devices", J Diabetes Sci Technol., vol. 4, no. 3, pp. 522-531, May, 2010.
• [9] A. Bode, "Development of the SoloSTAR insulin pen device: design verification and validation", Expert Opin Drug Del, vol. 6, no. 1, pp. 103-112, Dec, 2009.
• [10] D. A. Nadeau, C. Campos, M. Niemeyer, T. Bailey, "Healtcare professional and patient assessment of a new prefilled insulin pen versus two widely available prefilled insulin pens for ease of use, teaching and learning", Curr Med Res Opin, vol. 28, no. 1, pp. 3-13, Jan, 2012.