Araştırma Makalesi
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Yıl 2013, Cilt: 13 Sayı: 2, 1641 - 1645, 25.12.2013

Öz

Kaynakça

  • Hansen, K. M., Thundat, T., “Microcantilever biosensors”, Methods, Vol: 37, No: 1, pp. 57-64, 2005.
  • Frometa, N. R., “Cantilever biosensors”, Biotecnologia Aplicada, Vol: 23, No: 4, pp. 320-323, 2006.
  • Bais, B., Rahim, R. A., Majlis, B. Y., “Finite element and system level analyses of piezoresistive microcantilever for biosensing applications”, Australian Journal of Basic & Applied Sciences, Vol: 5, No: 12, pp. 1038-1046, 20 Lim, Y. C., Kouzani, A. Z., Duan, W., Kaynak, A., “Effects of design parameters on sensivity of microcantiilever biosensors”, IEEE International Conference on Complex Medical Engineering-ICME, 2010.
  • Alvarez, M., Lechuga, L. M., “Microcantilever-based platforms as biosensing tools”, Analyst, Vol: 135, No: 5, pp. 827-836, 2010.
  • Ziegler, C., “Cantilever based biosensors”, Analytical & Bioanalytical Chemistry. Vol: 379, No: 7/8, pp. 946-959, 200 Villanueva, G., Rius, G., Montserrat, J., Murano, F. P., Bausells, J., “Piezoresistive microcantilevers for biomolecular force detection”, SCED, Spanish Conference on Electron Devices IEEE, 2007.
  • He, J. H., Li, Y. F., ”High sensivity piezoresistive cantilever sensor for biomolecular detection” , Journal of Physics: Conference Series, Vol: 34, pp. 429-435, 2006.
  • Johnson, B. N., Mutharasan, R., “Biosensing using dynamic - mode cantilever sensors: A review”, Biosensors and Bioelectronics , Vol: 32, No: 1, pp. 1-18, 2011.
  • Datar, R., Kim, S., Jeon, S., Hesketh, P., Manalis, S., Boisen, A., Thundat, T., “Cantilever sensors: Nanomechanical tools for diagnostics”, MRS Bulletin, Vol: 34, No: 6, pp449-454, 2009.
  • Mutyala, M. S. K., Bandhanadham, D., Pan, L., Pendyala, V. R., Ji, H. F., “Mechanical and electronic approaches to improve the sensivity of microcantilever sensors”, Acta Mech Sin, Vol: 25, No: 1, pp. 1-12, 2009.
  • Yang, M., Zhang, X., Vafai, K., Ozkan, C. S., “High sensitivity piezoresistive cantilever design and optimization for analyte-receptor binding”, Journal of Micromechanics and Microengineering, Vol: 13, No: 6, pp. 864-872 , 200 Kale, N. S., Nag, S., Pinto, R., Rao, V. R., “Fabrication and characterization of a polymeric microcantilever with an encapsulated hotwire cvd polysilicon piezoresitor”, Journal of Microelectromechanical Systems, Vol: 18, No:1, pp. 7987, 2009.
  • Park, S. J., Doll, J. C., Pruitt, B., “Piezoresistive cantilever performance - part 1: Analytical model for sensivity”, Journal of Microelectromechanical Systems, Vol: 19, No:1, pp. 137-148, 2010..
  • Thilagar, S. H., Kalairasi, A. R., “Design, simulation and analysis of cantilever sensor for in-vitro LDL detection”, Sensors & Transducers Journal, Vol: 130, No: 7, pp. 136141, 2011.
  • Rahim, R. A., Bais, B., Majlis, B. Y., “Design and analysis of MEMS piezoresistive SiO2 cantilever based sensor with stress concentration region for biosensing applications”, IEEE International Conference on Semiconductor Electronics, ICSE 2008, pp. 211-215, 2008.
  • Senturia, S. D., Microsystem Design, Kluwer Acadamic, 200 Kassegne, S., Madou, M., Whitten, R., Zoval, J., Mather, E., Sarkar, K., Hodko, D., Maity, S., “Design issues in SOIbased high sensivity piezoresistive cantilever devices”, Proc. SPIE, Vol: 4693, pp. 588-597, 2002.
  • Sacu, I. E., 2012. INVESTIGATION OF BIOMEDICAL APPLICATIONS OF MEMS, M.S. Thesis, Kayseri, 2012.
  • Chivukula, V., Wang, M., Ji, H. F., Khaliq, A., Fang, J., Varahramyan, K., “Simulation of SiO2-based piezoresitive microcantilevers”, Sensors and Actuators A: Physical, Vol: 125, No: 2, pp. 526–533 Elsevier, 2006.
  • Liu, C., Foundations of MEMS, Chapter 6, Pearson, 2006.
  • Ibrahim Ethem SACU was born in Kayseri, Turkey. He received the B.Sc. and M.Sc. degrees in Electrical & Electronics Engineering from the Erciyes University in 2010 and 2012, respectively. Since 2010, he has been a member of academic staff with Erciyes University, Engineering Faculty, Biomedical
  • Dept., Kayseri, Turkey. His current research interests include medical electronics, biosensors and circuit design. Mustafa ALCI was born in Kayseri, Turkey, in 1957. He graduated at the Electronic Dept. of the Technology Faculty, Gazi University, Ankara, in 1979. Then he received the B.Sc. degree from Erciyes University, Kayseri, in 1983, M.Sc. degree from the Middle East Technical University, Ankara, in 1986 and Ph.D. degree from Erciyes University, Kayseri, in 1989, respectively, all in Electrical & Electronics Engineering. Since 1979, he is a member of academic staff with Erciyes University
  • Engineering Faculty, Electronic Engineering Dept., Kayseri, Turkey. His current research interests include image processing, noise and coding artifacts suppression, fuzzy systems, medical electronics, chaotic systems and circuit design.

DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR

Yıl 2013, Cilt: 13 Sayı: 2, 1641 - 1645, 25.12.2013

Öz

Microcantilevers are one of the basic micromechanical structures. They are fixed at one ends and the other ends can move freely like a diving board. Their sizes are in the micrometer and nanometer ranges. Microcantilevers are called microcantilever sensors when their surfaces are functionalized to detect specific molecules. Since these sensors have offered remarkable possibilities in detection, they have been used in many fields such as clinical diagnosis, drug screening and pathogen detection. In the microcantilever sensors, various detection methods are available such as piezoresistive, optical, capacitive and piezoelectric. Each sensing method holds own advantages and disadvantages. By the advantage of allowing integration of the read-out electronics on the same chip, piezoresistive detection becomes prominent. So piezoresistive detection is chosen in this work and a basic piezoresistive microcantilever biosensor design is introduced. Furthermore, by making geometrical alterations on microcantilever and piezoresistive layer, effects of these variations upon sensitivity, vertical displacement and change in resistance are investigated. Additionally, effects of different shaped holes upon sensor are studied.

Kaynakça

  • Hansen, K. M., Thundat, T., “Microcantilever biosensors”, Methods, Vol: 37, No: 1, pp. 57-64, 2005.
  • Frometa, N. R., “Cantilever biosensors”, Biotecnologia Aplicada, Vol: 23, No: 4, pp. 320-323, 2006.
  • Bais, B., Rahim, R. A., Majlis, B. Y., “Finite element and system level analyses of piezoresistive microcantilever for biosensing applications”, Australian Journal of Basic & Applied Sciences, Vol: 5, No: 12, pp. 1038-1046, 20 Lim, Y. C., Kouzani, A. Z., Duan, W., Kaynak, A., “Effects of design parameters on sensivity of microcantiilever biosensors”, IEEE International Conference on Complex Medical Engineering-ICME, 2010.
  • Alvarez, M., Lechuga, L. M., “Microcantilever-based platforms as biosensing tools”, Analyst, Vol: 135, No: 5, pp. 827-836, 2010.
  • Ziegler, C., “Cantilever based biosensors”, Analytical & Bioanalytical Chemistry. Vol: 379, No: 7/8, pp. 946-959, 200 Villanueva, G., Rius, G., Montserrat, J., Murano, F. P., Bausells, J., “Piezoresistive microcantilevers for biomolecular force detection”, SCED, Spanish Conference on Electron Devices IEEE, 2007.
  • He, J. H., Li, Y. F., ”High sensivity piezoresistive cantilever sensor for biomolecular detection” , Journal of Physics: Conference Series, Vol: 34, pp. 429-435, 2006.
  • Johnson, B. N., Mutharasan, R., “Biosensing using dynamic - mode cantilever sensors: A review”, Biosensors and Bioelectronics , Vol: 32, No: 1, pp. 1-18, 2011.
  • Datar, R., Kim, S., Jeon, S., Hesketh, P., Manalis, S., Boisen, A., Thundat, T., “Cantilever sensors: Nanomechanical tools for diagnostics”, MRS Bulletin, Vol: 34, No: 6, pp449-454, 2009.
  • Mutyala, M. S. K., Bandhanadham, D., Pan, L., Pendyala, V. R., Ji, H. F., “Mechanical and electronic approaches to improve the sensivity of microcantilever sensors”, Acta Mech Sin, Vol: 25, No: 1, pp. 1-12, 2009.
  • Yang, M., Zhang, X., Vafai, K., Ozkan, C. S., “High sensitivity piezoresistive cantilever design and optimization for analyte-receptor binding”, Journal of Micromechanics and Microengineering, Vol: 13, No: 6, pp. 864-872 , 200 Kale, N. S., Nag, S., Pinto, R., Rao, V. R., “Fabrication and characterization of a polymeric microcantilever with an encapsulated hotwire cvd polysilicon piezoresitor”, Journal of Microelectromechanical Systems, Vol: 18, No:1, pp. 7987, 2009.
  • Park, S. J., Doll, J. C., Pruitt, B., “Piezoresistive cantilever performance - part 1: Analytical model for sensivity”, Journal of Microelectromechanical Systems, Vol: 19, No:1, pp. 137-148, 2010..
  • Thilagar, S. H., Kalairasi, A. R., “Design, simulation and analysis of cantilever sensor for in-vitro LDL detection”, Sensors & Transducers Journal, Vol: 130, No: 7, pp. 136141, 2011.
  • Rahim, R. A., Bais, B., Majlis, B. Y., “Design and analysis of MEMS piezoresistive SiO2 cantilever based sensor with stress concentration region for biosensing applications”, IEEE International Conference on Semiconductor Electronics, ICSE 2008, pp. 211-215, 2008.
  • Senturia, S. D., Microsystem Design, Kluwer Acadamic, 200 Kassegne, S., Madou, M., Whitten, R., Zoval, J., Mather, E., Sarkar, K., Hodko, D., Maity, S., “Design issues in SOIbased high sensivity piezoresistive cantilever devices”, Proc. SPIE, Vol: 4693, pp. 588-597, 2002.
  • Sacu, I. E., 2012. INVESTIGATION OF BIOMEDICAL APPLICATIONS OF MEMS, M.S. Thesis, Kayseri, 2012.
  • Chivukula, V., Wang, M., Ji, H. F., Khaliq, A., Fang, J., Varahramyan, K., “Simulation of SiO2-based piezoresitive microcantilevers”, Sensors and Actuators A: Physical, Vol: 125, No: 2, pp. 526–533 Elsevier, 2006.
  • Liu, C., Foundations of MEMS, Chapter 6, Pearson, 2006.
  • Ibrahim Ethem SACU was born in Kayseri, Turkey. He received the B.Sc. and M.Sc. degrees in Electrical & Electronics Engineering from the Erciyes University in 2010 and 2012, respectively. Since 2010, he has been a member of academic staff with Erciyes University, Engineering Faculty, Biomedical
  • Dept., Kayseri, Turkey. His current research interests include medical electronics, biosensors and circuit design. Mustafa ALCI was born in Kayseri, Turkey, in 1957. He graduated at the Electronic Dept. of the Technology Faculty, Gazi University, Ankara, in 1979. Then he received the B.Sc. degree from Erciyes University, Kayseri, in 1983, M.Sc. degree from the Middle East Technical University, Ankara, in 1986 and Ph.D. degree from Erciyes University, Kayseri, in 1989, respectively, all in Electrical & Electronics Engineering. Since 1979, he is a member of academic staff with Erciyes University
  • Engineering Faculty, Electronic Engineering Dept., Kayseri, Turkey. His current research interests include image processing, noise and coding artifacts suppression, fuzzy systems, medical electronics, chaotic systems and circuit design.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Makaleler
Yazarlar

İbrahim Sacu

Mustafa Alcı

Yayımlanma Tarihi 25 Aralık 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 13 Sayı: 2

Kaynak Göster

APA Sacu, İ., & Alcı, M. (2013). DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering, 13(2), 1641-1645.
AMA Sacu İ, Alcı M. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering. Aralık 2013;13(2):1641-1645.
Chicago Sacu, İbrahim, ve Mustafa Alcı. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering 13, sy. 2 (Aralık 2013): 1641-45.
EndNote Sacu İ, Alcı M (01 Aralık 2013) DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering 13 2 1641–1645.
IEEE İ. Sacu ve M. Alcı, “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”, IU-Journal of Electrical & Electronics Engineering, c. 13, sy. 2, ss. 1641–1645, 2013.
ISNAD Sacu, İbrahim - Alcı, Mustafa. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering 13/2 (Aralık 2013), 1641-1645.
JAMA Sacu İ, Alcı M. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering. 2013;13:1641–1645.
MLA Sacu, İbrahim ve Mustafa Alcı. “DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR”. IU-Journal of Electrical & Electronics Engineering, c. 13, sy. 2, 2013, ss. 1641-5.
Vancouver Sacu İ, Alcı M. DESIGN OF A BASIC PIEZORESISTIVE MICROCANTILEVER BIOSENSOR. IU-Journal of Electrical & Electronics Engineering. 2013;13(2):1641-5.