Medicinal plants with reported anxiolytic and sedative activities in Nigeria: A systematic review

Yıl 2019, Cilt: 49 Sayı: 2, 92 - 104, 01.08.2019

Abdullahi Rabiu Abubakar Mainul Haque

Öz

DOI: 10.26650/IstanbulJPharm.2019.18008

Medicinal plants have been widely used in
folklore medicine in the treatment of various diseases such as mental and
neurological disorders. Mental disorders like anxiety and depression are very
common among Nigerian populace. The purpose of this review was to access and
evaluate several articles published on the anxiolytic and sedative properties
of medicinal plants in Nigeria and to find out the gaps left for further
research and drug development. Eighty-two publications available among Nigerian
Universities and Research Institutes between 2008 and 2018 were selected. Seven
electronic databases such as Nigerian Plant Database, HerbMed, AGRICOLA,
MedlinePlus, PubMed, ScienceDirect, and Springer-Link were thoroughly explored
from which 226 relevant articles were obtained using Google Scholar, Hotbot and
FreeFullPdf as search engines. A number of studies conducted to test for the
anxiolytic and sedative activity of medicinal plants in Nigeria were included.
Articles published between 2008 and 2018 were selected. The studies were
conducted in Nigeria. Research carried out before 2008 was not selected. All
publications with authorship outside Nigeria were excluded. Several medicinal
plants on which experiments were conducted were reported to have anxiolytic and
or sedative properties in Nigeria. Several medicinal plants have shown promise
as anxiolytic and sedative agents in laboratory animals’ studies. The majority
of these plants were used traditionally in the past to treat anxiety in
Nigeria. Further research on the efficacy and safety of these medicinal plants
could yield a more cost effective and perhaps safer alternative in the
treatment of anxiety among Nigerians.   

Cite this article as: Abubakar AR, Haque M
(2019). Medicinal plants with reported anxiolytic and sedative activities in
Nigeria: A systematic review. Istanbul J Pharm 49 (2): 92-104.

Anahtar Kelimeler

Anxiolytic, sedative, medicinal-plants, phytotheraphy, Nigeria

Kaynakça

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