A case of non-Hodgkin's lymphoma presenting as a large chest wall mass

Abstract

Malignant lymphoma as a solitary chest wall mass is rare. Although surgical resection is the main treatment modality for malignant chest wall tumors, the treatment of primary chest wall lymphomas is controversial. A 65-year-old male patient with an enlarging mass on the left side of his chest wall, which had first appeared four months before, applied to our hospital. The patient was directed to our polyclinic with a diagnosis of l a rge B-cell lymphoma after the biopsy. Following the clinical investigation, stage IIEB extranodal non-Hodgkin's lymphoma was determined, and after a palliative radiotherapy, eight cycles of chemotherapy were planned. However, shortly after the completion of the sixth cycle of chemotherapy, poor performance status developed secondary to chemotherapy and the patient was diagnosed with pulmonary embolus. Following the stop of chemotherapy after six cycles, a complete clinical remission and a nearly complete radiologic remission were achieved. The patient is still under follow-up and was free of disease at four months.

Keywords

• Middle Aged,Male,Biopsy,Lymphoma, Non-Hodgkin,Neoplasm Staging,Chemotherapy,Thoracic Wall

Göğüs duvarında büyük bir kitle şeklinde ortaya çıkan non-Hodgkin lenfoma olgusu

Öz

Göğüs duvarında izole kitle ile ortaya çıkan malign lenfoma olgularına nadir olarak rastlanmaktadır. Rezeksiyon göğüs duvarı malignitelerinde esas tedavi yöntemi olsa da primer göğüs duvarı lenfomalarının tedavisi tartışmalıdır. Altmış beş yaşındaki erkek hasta dört ay önce belirmeye başlayan ve gittikçe artan sol göğüs duvarındaki kitle nedeniyle hastanemize başvurdu. Hastanın yapılan biyopsisinde diffüz büyük B hücreli lenfoma (non-Hodgkin lenfoma) tanısı konularak polikliniğimize yönlendirildi. Klinik olarak evre IIEB kabul edilerek kısa süreli radyoterapi alan hastaya sekiz kür kemoterapi planlandı. Hastada altıncı kürden sonra kemoterapiye ikincil genel durum bozukluğu gelişti ve olası pulmoner emboli tanısı konuldu. Performans bozukluğu nedeniyle kemoterapisi kesilen hastada altı kür sonrasında yapılan değerlendirmede klinik tam yanıt ve radyolojik tama yakın yanıt alındı. Hasta dört aydır hastalıksız olarak takip edilmektedir.

Anahtar Kelimeler

• Göğüs duvarı tümörü, izole kitle, kemoterapi, non-Hodgkin lenfoma

Kaynakça

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