Lacrimal gland adenoid cystic carcinoma treated with intraarterial chemotherapy

Abstract

Adenoid cystic carcinoma is a malignant tumor of glandular tissue and progresses with local relapse and distant metastasis. In this report, we present a case of lacrimal gland adenoid cystic carcinoma who treated by multimodal approach with intraarterial chemotherapy. A 32-year-old woman was diagnosed with adenoid cystic carcinoma (solid variant) of the left lacrimal gland. Neoadjuvant intraarterial cisplatin, intravenous doxorubicin, and orbital exenteration were performed. The patient was followed for 32 months without relapse. Achievement of long-time survival for this disease supports studies that show benefit of intraarterial chemotherapy.

Keywords

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İntraarteriyel kemoterapi ile tedavi edilen lakrimal gland adenoid kistik karsinomu olgusu

Öz

Adenoid kistik karsinom (AKK) lokal nüks ve uzak metastazlarla seyreden glanduler dokuların malign tümörüdür. Bu yazıda, intraarteriyel kemoterapi ile beraber multimodal yaklaşımla tedavi edilen bir lakrimal gland AKK olgusu sunuldu. Otuz iki yaşındaki kadın hastaya sol lakrimal gland AKK (solid varyant) tanısı konuldu. Neoadjuvan intraarteriyel sisplatin ve intravenöz doksorubisin tedavisinden sonra orbita eksanterasyonu uygulandı. Hasta 32 ay sonra halen hastalıksız izlemdedir. Söz konusu hastalık için iyi bir hastalıksız sağkalım süresi sağlanması, lakrimal gland AKK tedavisinde intraarteriyel kemoterapinin yararını gösteren yayınları destekler durumdadır.

Anahtar Kelimeler

• Adenoid kistik karsinom, intraarteryal kemoterapi, lakrimal gland

Kaynakça

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