Ovine Theileriosis Enhances Cardiovascular Disease Biomarkers in Naturally Infected Sheep (Ghezel breed) in West Azerbaijan, Iran
Öz
This study was aimed to evaluate the plasma levels of cardiovascular disease biomarkers in naturally infected theileriosis in sheep (Ghezel breed). Theileria species are known to be ruminant blood parasites and involves deleterious effects in the livestock. Blood samples were collected from 30 selected sheep (Ghezel breed), naturally infected with theileriosis (infected group) and same number non-infected ones. Hematological parameters and the plasma concentrations of cardiac troponin I (cTnI), creatine kinase-MB (CK-MB) and homocysteine (Hcy) were determined in all samples. The results revealed that significant increase (P>0.01) in the level of cTnI, CK-MB, and Hcy concentrations in infected sheep compared with non-infected ones. In addition, cardiovascular biomarkers levels increased with aging and parasitemia rate (P<0.01). In conclusion, theileriosis provides evidence of the progression of cardiovascular biomarkers by aging and following elevation of parasitemia rate in Ghezel breed sheep and seems that further attention should be paid on this issue.
Anahtar Kelimeler
Kaynakça
- Andrade, Z.A., Andrade, S.G., Correa, R., Sadiqursky, M., Ferrans, V.J., 1994. Myocardial changes in acute Trypanosoma cruzi infection. American Journal of Pathology 144, 1403-1410.
- Boswood, A., 2009. Biomarkers in cardiovascular disease: Beyond natriuretic peptides. Journal of Veterinary Cardiology 11, 23-32.
- Chango, A., Abdennebi-Najar, L., 2011. Folate metabolism pathway and Plasmodium falciparum malaria infection in pregnancy. Nutrition Reviews 69, 34-40.
- Chillemi, R., Zappacosta, B., Simporè, J., Persichilli, S., Musumeci, M., Musumeci, S., 2004. Hyperhomocysteinemia in acute Plasmodium falciparum malaria: an effect of host-parasite interaction. Clinica Chimica Acta 348, 113-120.
- Col, R., Uslu, U., 2007. Changes in selected serum components in cattle naturally infected with Theileria annulata. Bulletin of the Veterinary Institute in Pulawy 51, 15-18.
- Diana, A., Guglielmini, C., Candini, D., Pietra, M., Cipone, M., 2007. Cardiac arrhythmias associated with piroplasmosis in the horse: A case report. Veterinary Journal 174, 193-195.
- Diniz, P.P.V.P., Morais, H.S.A., Breitschwerdt, E.B., Schwartz, D.S., 2008. Serum cardiac troponin I concentration in dogs with ehrlichiosis. Journal of Veterinary Internal Medicine 22, 1136-1143.
- Fartashvand, M., Nadalian, M.G., Sakha, M., Safi, S., 2013. Elevated Serum Cardiac Troponin I in Cattle with Theileriosis. Journal of Veterinary Internal Medicine 27, 194-199.
Ayrıntılar
Birincil Dil
Türkçe
Konular
Sağlık Kurumları Yönetimi
Bölüm
Araştırma Makalesi
Yazarlar
Kaveh Azımzadeh
Department of Clinical Sciences, Veterinary Faculty, Urmia Branch, Islamic Azad University, Urmia, IRAN
Yayımlanma Tarihi
1 Ocak 2017
Gönderilme Tarihi
20 Temmuz 2016
Kabul Tarihi
7 Eylül 2016
Yayımlandığı Sayı
Yıl 2017 Cilt: 43 Sayı: 1