TAVŞANLARDA ENDOTRAKEAL ENTUBASYON TEKNiĞİ KULLANILARAK İNHALASYON ANESTEZİSİ UYGULAMASI

Yıl 2005, Cilt: 31 Sayı: 1, 139 - 148, 08.03.2013

Özlem Güzel , E. Perk Mustafa Aktaş , Yalçın Devecioğlu

Öz

ÖZET

Bu çalişmada 12 tavşan kullanıldı. Olgulara intravenöz (IV) yol ile 0.5 mg/kg diazepam premedikasyonu yapıldı. Anestezi induksiyonunda 10 mg/kg IV propofol kullanıldı ve sonrasında tavşanlar entübe edildi. Entübasyonu takiben sevofluranla inhalasyon anestezisi uygulandı.

Çalışmada, tavşanlarda endotrakeal entubasyon tekniği ile klinik uygulamalarda ve deneysel çalışmalarda güvenli ve kontrollü bir anestezi sağlanabileceği sonucuna varılmıştır.

Anahtar Kelimeler: Endotrakeal entubasyon, inhalasyon anestezisi, tavşan.

 

ABSTRACT

ADMINISTRATION OF INHALATION ANAESTHESIA IN RABBITS USING THE ENDOTRACHEAL INTUBATION TECHNIQUE

This study carried out on 12 rabbits. Intravenous (IV) diazepam premedication at a dose of 0.5mg/kg was given to the animals. Anaesthesia induction was performed using propofol at a dose of l0 mg/kg IV and the rabbits were intubated subsequently. After intubation, inhalation anaesthesia was administered using sevoflurane.

In this study, it has been concluded that by using the endotracheal technique in rabbits, a reliable and controlled anaesthesia can be achieved in clinical cases and experimental studies.

Key Words: Endotracheal intubation, inhalation anesthesia, rabbit.

 

Anahtar Kelimeler

Kndotrakeal entübasyon. inhalas>on anestezisi, tavşan

Kaynakça

• Alexander, D.J., Clark, G . C . : A simple method of oral endotracheal intubation in rabbits. Lab A n i m Sci., 1980; 30 (5): 871-873.
• Borkovvski, R., K a r a s , A.Z.: Sedation and anesthesia o f pet rabbits. Clin Tech Small A n i m Pract., 1999; 14 (1): 44-49.
• Clutton, E . : Anaesthetic Equipment. In: Manual o f Small Animal Anaesthesia and Analgesia. Ed. Seymour, C , Gleed, R., Cheltenham. B S A V A , 1999, 19-41.
• F i c k , T . E . , Schalm, S.W.: A simple technique for endotracheal intubation in rabbits. Lab Anim., 1987; 21 (3): 265-266.
• Flecknell, P.: Rabbits. Rodents and Ferrets. In: Manual of Small Animal Anaesthesia and Analgesia. Ed.: Seymour, C , Gleed, R., Cheltenhan, B S A V A , 1999.295-304.
• Fujita, M., Morimoto, Y., Ishihara, M., Shimizu, M., Takase, B., Maehara, T . , Kikuchi, M.: A new rabbit model o f myocardial infarction without endotracheal intubation. J Surg Res., 2004; 116 (1):124-128.
• Gonzalez Gıl, A.s Illera, J . C . , Silvan, G., Illera, M.: Plasma glucocorticoid concentrations after fentanyl-droperidol, ketamine-xylazine and ketamine- diazepam anaesthesis in New Zealand white rabbits. Veterinary Record, 2 0 0 1 ; 148: 784-786.
• Güzel, Ö., Perk, E . C . : Köpeklerde genel anestezi prosedürü ve intraoperatif periyotta rastlanan kardiyak ritm bozukluklarının tanı ve sağaltımı. İstanbul Üniv. Vet. Fak. Derg., 2002; 28 (2): 381-401.
• Holmes, D.D.: Rabbits. In: Clinacal Laboratory Animal Medicine. The Iovva State University Press., Iovva, 1990, 45-58.
• Özköse, Z., Menteş, B.B., Görgül, A.: Deney Hayvanlarında Anestezi. Barok Ofset, Ankara, 1998.
• Perk, E . C . , D ü z g ü n , O., Güzel, O., Mutlu, Z.: Domuzlarda inhalasyon anestezisi. İstanbul Üniv. Vet. Fak. Derg., 2004; 30 (1): 47-59.
• Skarda, T . R . , Bednarski, R . M . , M u i r , W.W., Hubbell, J . A . E . : Handbook of Veterinary Anesthesia. In Chapter 23. Second Edition., Mosby, St. Louis, 1995; 341-371.
• Takeda, T . , Makita, K., Ishikavva, S., kaneda, K., Yokoyama, K., Amaha, K . : Uptake and elimination o f sevollurane in rabbit tissues-an in vivo magnetic resonance spectroscopy study. Can J Anaesth., 2000; 47 (6): 579-584.
• Taoda, M., Hashimoto, K., Karasavva, F . , Satoh, T . : The effect of sevoflurane and enflurane on renal sympathetic nerve activity in sinoaortic denerved rabbits. Masui.,2000; 49 (12): 1328-1332. 14$ Özlem GÜZEL - E. Cem PERK - Mustafa AKTAŞ - Yalçın DEVECİOĞLU
• Tennant, B.: Small Animal Formulary. Second Edition. Hampshire. B S A V A , 1997.
• Thurmon, C . J . , Tranquilli, J.W., Benson, J.G.: Lump&Jones" Veterinary Anesthesia. In: Chapter 2 1 . W i l I i a m s & W i k i n s , Baltimore, 1996; 686-735.
• VVeinstein, C . H . , Fujimoto, J . L . , VVishner, R . E . , \ewton, P.O.: Anesthesia o f six-week-old New Zealand White rabbits for thoracotomy. Contemp Top Lab Anim Sci., 2000; 39 (3): 19-22.
• X u , J . M . , Chang, Y . T . , Hu, D.X.: Protective effects of sevoflurane pretreatment on myocardial isehemia-reperfusion injury in rabbits. Hunan Y i Ke Da Xue Xue Bao., 2 0 0 1 ; 28; 2 6 ( 1 ) : 79-82.