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A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds

Yıl 2015, Cilt: 41 Sayı: 2, 185 - 190, 01.07.2015

Öz

By X-ray computed tomography (CT), density characteristics of the tibiae bones in 25 experimental adult male rats were studied after their tibiae bones have experimentally fractured and then repaired by osteosynthesis using different implants. According to the data that was obtained by computed tomography, it has been defined that bone densities depend on the type of the implant and the chemical composition of the coating which is applied on the surface of the implant. Thus, average values of the density of the tibiae bones in the experimental rats with implants coated with a combination of titanium and hafnium nitrides were not different from the density values of the intact bones. At the same time, the densities of the tibiae in rats with implants made of copper and implants coated with a combination of titanium and zirconium nitrides were 1.5-2 times lower than those of the intact bones. This leads us to conclude that implants coated with titanium and hafnium nitrides are biologically and chemically inert because less pathologic changes in the bone tissue were observed, in contrast to the copper-based implants and those where the coating contains zirconium.

Kaynakça

  • Abdullin, I.S., Mironov, M., Garipova, G.I., 2004. Germicidal and biologically resistant coatings for medical implants and instruments. Med Technology 4, 20-22.
  • Akhtyamov, I.F., Gatina, E.B., Kadyrov, F.F., Shaehov, M.F., 2012. Study the interaction of a biocompatible coating of a mixture of metal nitrides of group IV with living tissues. Herald of Kazan Technological University 15 (20), 176 -179.
  • Akhtyamov, I.F., Shakirova, F.V., Gatina, E.B., Zubairova, L.D., Aliyev, E.I. 2013. Evaluation of the acute phase in experimental osteosynthesis with implants coated with bioinert metal superhard nitrides. Genius Orthopedics Academician GA Ilizarov 4, 80-83.
  • Akhtyamov, I.F., Shakirova, F.V., Gatina, E.B., Manirambona, J.C., 2014. Clinical study of impact of implants made of different types of metals on the physical state of the experimental animals. Genius Orthopedii Moscow 4, 36-43.
  • Amstutz, H.C., Campbell, P., Kossovsky, N., Clarke, I.C., 1992. Mechanism and clinical significance of wear debris induced osteolysis. Clinical Orthopaedics and Related Research 276, 7-18.
  • Brandes, E.A., Brook, G.B., 1992. Smithells Metals Reference Book. 7th ed. Oxford, Butterworth-Heinemann. pp. 26- 32.
  • Cooke, F.W., 1992. Ceramics in orthopedic surgery. Clinical Orthopaedics and Related Research 276, 135-146.
  • Davidson, J.A., 1993. Characteristics of metal and ceramic total hip bearing surfaces and their effect on long-term ultra high molecular weight polyethylene wear. Clinical Orthopaedics and Related Research 294, 361-378.
  • Dyachkova, G.V., Diachkov, K.A., Aleksandrov, S.M., Larionov, T.A., Klyushin, N.M., 2013. Assessment of bone quality by computed tomography in patients with chronic osteomyelitis. Journal Traumatology and Orthopaedics 3, 88-95.
  • Dyachkova, G.V., Mitin, Y.L., 2011. Semiotics of proliferative changes in the femur chronic osteomyelitis that developed after acute osteomyelitis. Journal of Traumatology and Orthopedics 4, 60-64.
  • Edelson, J.G., 1984. Congenital dislocation and computerized axial tomography. Journal of Bone and Joint Surgery, 66 (4), 472-478.
  • Hermawan, H., Mantovani, D., 2009. Degradable metallic biomaterials: The concept, current developments and future directions. Minerva Biotecnologica 21, 207-216.
  • Horowitz, S.M., Purdon, M.A., 1995. Mechanisms of cellular recruitment inaseptic loosening of prosthetic joint implants. Calcified Tissue International 57, 301-305.
  • Lewis, N., Nelson, L., Lewin, N., Howland, M.A., Hoffman, R., Goldfrank, L., Flomenbaum, N., 2002. Goldfrank's Toxicologic McGraw-Hill, Chapter 82C.
  • (7th Edition), “Copper,”
  • Lidin, R.A, Molochko, V.A., Andreeva, L.L., 2000. Chemical properties of non organic elements. Chemistry. Moscow. pp. 361-364.
  • Pappas, M.J., Makris, G., Buechel, F.F., 1995. Titanium nitride ceramic film against polyethylene: a 48 million cycle wear test. Clinical Orthopaedics and Related Research 317, 64-70.
  • Peterson, C.D., Hillberry, B.M., Heck, D.A., 1988. Component wear of total knee prostheses using Ti-6Al-4V, titanium nitride coated Ti-6Al-4V, and cobalt-chromium- molybdenum femoral components. Journal of Biomedical Materials Research 22 (10), 887-903.
  • Steinemann, S.G., 1996. Metal implants and surface reactions. Injury 27 (Suppl3), 16-22.
  • Summer, B., Fink, U., Zeller, R., Rueff, F., 2007. Patch test reactivity to a cobalt-ch romium-molybdenum alloy and stainless steel in metal-allergic patients in correlation to the metal ion release. Contact Dermatitis 57 (1), 35-39.
  • Zagorodnii, N.V., Bukhtin, K.M., Kudinov, O.A., Chragyan, G.A., 2013. Reaction to cobalt as a cause of revision knee arthroplasty. Journal of Traumatology and Orthopedics 2, 65-68.

Transosseöz Osteosentez Altındaki Kemik Dokusunun Dansitometrik Parametrelerinin Aşırı Sert Bileşiklerle Kaplanmış Deneysel İmplantlar Kullanarak Karşılaştırmalı Çalışması

Yıl 2015, Cilt: 41 Sayı: 2, 185 - 190, 01.07.2015

Öz

Erişkin, erkek 25 deney sıçanının tibia kemikleri deneysel olarak kırılıp, sonra çeşitli implantlar kullanılarak osteosentez yoluyla düzeltilmesini takiben X-ışın bilgisayarlı tomografi (CT) kullanılarak tibia kemiklerinin dansite özellikleri araştırıldı. Bilgisayarlı tomografi ile elde edilen veriler ışığında, kemik yoğunluklarının implant tipine ve implantın yüzeyine uygulanan kaplamanın kimyasal kompozisyonuna bağlı olduğu tanımlandı. Böylelikle, titanyum ve hafniyum nitrit kombinasyonu ile kaplı implantları bulunan sıçanlardaki tibia kemikleri yoğunluklarının ortalama değerleri dokunulmamış kemiklerin yoğunluk değerlerinden farklı değildi. Aynı zamanda, bakırdan yapılmış implantlı ile titanyum ve zirkonyum nitrit kombinasyonu ile kaplanmış implantlı sıçanlardaki tibia yoğunlukları dokunulmamış kemiklerdekilerden 1,5-2 kat daha düşüktü. Bu da bizi, bakır-bazlı implantlara ve kaplamanın zirkonyum içerdiği implantlara oranla kemik dokusunda daha az patolojik değişiklikler gözlemlendiğinden titanyum ve hafniyum nitrit ile kaplanmış implantların biyolojik ve kimyasal olarak inert oldukları sonucuna varıldı.

Kaynakça

  • Abdullin, I.S., Mironov, M., Garipova, G.I., 2004. Germicidal and biologically resistant coatings for medical implants and instruments. Med Technology 4, 20-22.
  • Akhtyamov, I.F., Gatina, E.B., Kadyrov, F.F., Shaehov, M.F., 2012. Study the interaction of a biocompatible coating of a mixture of metal nitrides of group IV with living tissues. Herald of Kazan Technological University 15 (20), 176 -179.
  • Akhtyamov, I.F., Shakirova, F.V., Gatina, E.B., Zubairova, L.D., Aliyev, E.I. 2013. Evaluation of the acute phase in experimental osteosynthesis with implants coated with bioinert metal superhard nitrides. Genius Orthopedics Academician GA Ilizarov 4, 80-83.
  • Akhtyamov, I.F., Shakirova, F.V., Gatina, E.B., Manirambona, J.C., 2014. Clinical study of impact of implants made of different types of metals on the physical state of the experimental animals. Genius Orthopedii Moscow 4, 36-43.
  • Amstutz, H.C., Campbell, P., Kossovsky, N., Clarke, I.C., 1992. Mechanism and clinical significance of wear debris induced osteolysis. Clinical Orthopaedics and Related Research 276, 7-18.
  • Brandes, E.A., Brook, G.B., 1992. Smithells Metals Reference Book. 7th ed. Oxford, Butterworth-Heinemann. pp. 26- 32.
  • Cooke, F.W., 1992. Ceramics in orthopedic surgery. Clinical Orthopaedics and Related Research 276, 135-146.
  • Davidson, J.A., 1993. Characteristics of metal and ceramic total hip bearing surfaces and their effect on long-term ultra high molecular weight polyethylene wear. Clinical Orthopaedics and Related Research 294, 361-378.
  • Dyachkova, G.V., Diachkov, K.A., Aleksandrov, S.M., Larionov, T.A., Klyushin, N.M., 2013. Assessment of bone quality by computed tomography in patients with chronic osteomyelitis. Journal Traumatology and Orthopaedics 3, 88-95.
  • Dyachkova, G.V., Mitin, Y.L., 2011. Semiotics of proliferative changes in the femur chronic osteomyelitis that developed after acute osteomyelitis. Journal of Traumatology and Orthopedics 4, 60-64.
  • Edelson, J.G., 1984. Congenital dislocation and computerized axial tomography. Journal of Bone and Joint Surgery, 66 (4), 472-478.
  • Hermawan, H., Mantovani, D., 2009. Degradable metallic biomaterials: The concept, current developments and future directions. Minerva Biotecnologica 21, 207-216.
  • Horowitz, S.M., Purdon, M.A., 1995. Mechanisms of cellular recruitment inaseptic loosening of prosthetic joint implants. Calcified Tissue International 57, 301-305.
  • Lewis, N., Nelson, L., Lewin, N., Howland, M.A., Hoffman, R., Goldfrank, L., Flomenbaum, N., 2002. Goldfrank's Toxicologic McGraw-Hill, Chapter 82C.
  • (7th Edition), “Copper,”
  • Lidin, R.A, Molochko, V.A., Andreeva, L.L., 2000. Chemical properties of non organic elements. Chemistry. Moscow. pp. 361-364.
  • Pappas, M.J., Makris, G., Buechel, F.F., 1995. Titanium nitride ceramic film against polyethylene: a 48 million cycle wear test. Clinical Orthopaedics and Related Research 317, 64-70.
  • Peterson, C.D., Hillberry, B.M., Heck, D.A., 1988. Component wear of total knee prostheses using Ti-6Al-4V, titanium nitride coated Ti-6Al-4V, and cobalt-chromium- molybdenum femoral components. Journal of Biomedical Materials Research 22 (10), 887-903.
  • Steinemann, S.G., 1996. Metal implants and surface reactions. Injury 27 (Suppl3), 16-22.
  • Summer, B., Fink, U., Zeller, R., Rueff, F., 2007. Patch test reactivity to a cobalt-ch romium-molybdenum alloy and stainless steel in metal-allergic patients in correlation to the metal ion release. Contact Dermatitis 57 (1), 35-39.
  • Zagorodnii, N.V., Bukhtin, K.M., Kudinov, O.A., Chragyan, G.A., 2013. Reaction to cobalt as a cause of revision knee arthroplasty. Journal of Traumatology and Orthopedics 2, 65-68.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Galimzyan Kabırov Bu kişi benim

Faina Shakırova Bu kişi benim

Jean Manırambona Bu kişi benim

Ildar Akhtıamov Bu kişi benim

Elmira Gatına Bu kişi benim

Rustem Zakırov Bu kişi benim

Nailya Munırova Bu kişi benim

Yayımlanma Tarihi 1 Temmuz 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 41 Sayı: 2

Kaynak Göster

APA Kabırov, G., Shakırova, F., Manırambona, J., Akhtıamov, I., vd. (2015). A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 41(2), 185-190. https://doi.org/10.16988/iuvfd.2015.37584
AMA Kabırov G, Shakırova F, Manırambona J, Akhtıamov I, Gatına E, Zakırov R, Munırova N. A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds. iuvfd. Ağustos 2015;41(2):185-190. doi:10.16988/iuvfd.2015.37584
Chicago Kabırov, Galimzyan, Faina Shakırova, Jean Manırambona, Ildar Akhtıamov, Elmira Gatına, Rustem Zakırov, ve Nailya Munırova. “A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated With Superhard Compounds”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 41, sy. 2 (Ağustos 2015): 185-90. https://doi.org/10.16988/iuvfd.2015.37584.
EndNote Kabırov G, Shakırova F, Manırambona J, Akhtıamov I, Gatına E, Zakırov R, Munırova N (01 Ağustos 2015) A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 41 2 185–190.
IEEE G. Kabırov, “A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds”, iuvfd, c. 41, sy. 2, ss. 185–190, 2015, doi: 10.16988/iuvfd.2015.37584.
ISNAD Kabırov, Galimzyan vd. “A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated With Superhard Compounds”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 41/2 (Ağustos 2015), 185-190. https://doi.org/10.16988/iuvfd.2015.37584.
JAMA Kabırov G, Shakırova F, Manırambona J, Akhtıamov I, Gatına E, Zakırov R, Munırova N. A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds. iuvfd. 2015;41:185–190.
MLA Kabırov, Galimzyan vd. “A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated With Superhard Compounds”. İstanbul Üniversitesi Veteriner Fakültesi Dergisi, c. 41, sy. 2, 2015, ss. 185-90, doi:10.16988/iuvfd.2015.37584.
Vancouver Kabırov G, Shakırova F, Manırambona J, Akhtıamov I, Gatına E, Zakırov R, Munırova N. A Comparative Study of Densitometric Parameters of the Bone Tissue Under Transosseous Osteosynthesis by Using Experimental Implants Coated with Superhard Compounds. iuvfd. 2015;41(2):185-90.