MENİSKEKTOMİ MATERYALLERİNDE HİSTOPATOLOJİK BULGULAR VE KALSİYUM DEPOLANMASI SIKLIĞI 142 ARTROSKOPİK MENİSKEKTOMİ

Öz

Dize ait meniskektomi materyallerinde yaş ve cinsiyet dağılımları yanısıra kalsiyum depolanması prevalansının belirlenmesi amaçlandı. Menisküs ve fibröz kartilaj dokusu eksize edilen 142 olgu erkek/kadın:76/66, ortalama yaş:43 kalsiyum depolanması ve diğer parametreleri belirlemek için incelendi. Menisküs doku örnekleri formalin fiksasyonu sonrası ışık mikroskobu ve polarize mikroskop ile histolojik olarak incelendi. Kalsiyum depolanması 8 %5.6 olguda izlendi. Kalsiyum depolanması için cinsiyet dağılımı açısından farklılık görülmedi. Kalsiyum depolanması olan olgular ileri yaş grubundaydı. Meniskektomi materyallerinde kalsiyum pirofosfat kristal depo hastalığı nadir değildir. Çalışma sonuçları inflamasyon ve kapiller proliferasyonun kalsiyum depolanması olanlarda olmayanlara oranla daha sık olduğunu göstermektedir. Yangısal değişikliklere ek olarak kalsiyum depolanmasının hiperparatiroidizm, hemokromatozis, hipotiroidizm ve Wilson hastalığı gibi sistemik olarak araştırılması gereken hastalıklarla arasıra birlikte olabilmesi nedeniyle, meniskektomi materyelleri disseke edilmeli ve olabilecek değişiklikleri belirlemek için mikroskobik olarak incelenmelidir

Anahtar Kelimeler

• Tibial menisküs,kondrokalsinozis,kalsiyum pirofosfat

HISTOPATHOLOGIC FINDINGS AND THE PREVALANCE OF CALCIUM DEPOSITION IN MENISCECTOMY MATERIALS. 142 ARTHROSCOPIC MENISCECTOMY

Abstract

We aimed to determine the prevalence of menisceal calcium deposition as well as its possible predilection for age and sex in meniscectomy materials of the knee. We reviewed tissue sections from 142 patients M/F: 76/66, mean age: 43 yrs to determine the frequency of meniscal and fibrous cartilage calcification and other parameters. Histological evaluation on meniscal samples after formalin fixation was carried out by light microscopy and polarized light microscopy. Calcium deposition was found in 8 5.6% patients. No sex difference was present for the calcium deposition. Increased prevalence of menisceal calcification with age was observed . CPPD Calcium pyrophosphate dihydrate crystal deposition disease of the knee is not infrequent in meniscectomy materials. The results of this study indicate that inflammation and capillary proliferation were seen more frequent in calcium deposition group than those without deposits. Meniscectomy materials should be dissected and reviewed microscopically for detection calcium deposition in addition to inflammatory changes, because of occasional association with diseases like hyperparathyroidism, hypothyroidism, hemochromatosis, Wilson disease that require systemic evaluation

Keywords

• Menisci-tibial,chondrocalcinosis,calcium pyrophosphate

Kaynakça

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