SHEEHAN SENDROMU: OLGU SUNUMU

Öz

Sheehan sendrom, empty sella sendromun önemli nedenlerinden biridir. Klinik seyir değişken olup, intrapartum veya postpartum kanama sonrası ani ya da sinsice yıllar sonra gelişen hipofizer yetmezlik şeklinde olabilir. Biz, 14 yıl önce geçirdiği ciddi intrapartum kanama sonrası yavaş seyirli panhipopituitarizme neden olan nadir Sheehan sendromlu bayan olguyu sunmaktayız

Anahtar Kelimeler

• Sheehan sendrom,empty sella,adrenal yetmezlik,panhipopituitarizm

SHEEHAN SYNDROM: A CASE REPORT

Öz

Sheehan’s syndrome is one of important causes of empty-sella syndrome. The clinical presentation is variable with sudden or insidiously developing pituitary insufficiency after intrapartum or postpartum haemorrhage in years. We present an elderly woman with Sheehan syndrome who had slowly progressive hypopituitarism after 14 years of a severe intrapartum haemorrhage

Anahtar Kelimeler

• Sheehan syndrom,empty sella,adrenal insufficiency,panhypopituitarism

Kaynakça

1. Kovacs K. Sheehan syndrome. Lancet 2003; 361 (8): 520–522.
2. Huang Y.-Y, Ting m-K, HSH BRS, Tsar JS.Demonstration of reserved anterior pituitary function among the patients with amenorrhea after postpartum hemorrhage. Gynecol Endocrinol 2000; 14: 99-104
3. Muller B, Trepp R, Diem P, Christ E. das Paradoxon der TSH-Erho hung bei Sheehan-Syndrom. Dtsch MedWochenschr 2002;127: 2610-2612.
4. Arai H (2006) Empty sella syndrome. Nippon Rinsho .Rewiew: 212-216
5. De Marinis L, Bonadonna S,Bianchi A, Maria G, Giustina A (2005) Primary empty sella. J. Clin. Endocrinol Metab 90:5471-5477
6. Kelestimur F. Sheehan’s syndrome. Pitutary 2003; 6:181-188
7. Goswami R, Kochupillai N, Crock PA, Jaleel A, Gupta N. Pituitary autoimmunity in patients with Sheehan’s syndrome. J Clin Endocrinol Metab 2002; 87: 4137-4141.
8. Oliveira JHA, Persani L, Beck-Peccoz P, Abucham J. Investigating the paradox of hypothyroidism and increased serum thyrotropin (TSH) levels in Sheehan’s syndrome: characterization of TSH carbohydrate content and bioactivity. J Clin Endocrinol Metab 2001; 86: 1694-1699.

9. Diederich S, Franzen NF, Bahr V, Oelkers W. Severe hyponatremia due to hypopituitarism with adrenal insufficiency: report on 28 cases. Europ J Endoc 2003; 6: 609-617.
10. Orrego JJ, Barkan AL. Pituitary disorders. Drug treatment options. Drugs 2000; 59: 93-106.