Chitosan Skalp Kesisinde Kullanılmalı mı?

Yıl 2016, Cilt: 1 Sayı: 1, 1 - 6, 15.08.2016

İsmail Altintop , Mehmet Yilmaz

Öz

Kafa
travması nedeniyle 20 yaşındaki erkek hasta 112 tarafından acil servisimize
getirilmiştir. Hastada, sol pariyetal bölge arkasından başlayıp sağ
oksipitotemporal bölgeye uzanan yarımay şeklinde yaklaşık 15 cm’lik tam kat
skalp kesisi mevcuttu. Ambulansta basınçlı kompres uygulanmasına rağmen kanam
durdurulamamıştı. Kanama kontrolünün zor olduğu ve kanamanın chitosan
yardımıyla durdurulduğu deneyimimizi paylaşmak için bu vakayı hazırladık.

Anahtar Kelimeler

Chitosan, kanama, scalp kesisi

Kaynakça

• 1. Atalan N. Hemostatic Drugs. Journal of Cardio-Vascular-Thoracic Anaesthesia and Intensive Care Society [Internet]. 2014;20(1):1–6. Available from: http://www.gkda.org.tr/index.php?option=com_content&view=article&id=827:mart-2014-march-2015&catid=60:duyurular&Itemid=283
• 2. Barnard J, Millner R. A Review of Topical Hemostatic Agents for Use in Cardiac Surgery. Annals of Thoracic Surgery [Internet]. Elsevier Inc.; 2009;88(4):1377–83. Available from: http://dx.doi.org/10.1016/j.athoracsur.2009.02.092
• 3. Archana D, Dutta J, Dutta PK. Evaluation of chitosan nano dressing for wound healing: Characterization, in vitro and in vivo studies. International journal of biological macromolecules. Elsevier; 2013;57:193–203.
• 4. Moura LIF, Dias AMA, Suesca E, Casadiegos S, Leal EC, Fontanilla MR, et al. Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. Elsevier; 2014;1842(1):32–43.
• 5. Momoh FU, Boateng JS, Richardson SCW, Chowdhry BZ, Mitchell JC. Development and functional characterization of alginate dressing as potential protein delivery system for wound healing. International journal of biological macromolecules. Elsevier; 2015;81:137–50.
• 6. Kumar MNVR. A review of chitin and chitosan applications. Reactive and functional polymers. Elsevier; 2000;46(1):1–27.
• 7. Dai T, Tanaka M, Huang Y-Y, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert review of anti-infective therapy. Taylor & Francis; 2011;9(7):857–79.
• 8. Pozza M, Millner RWJ. Celox (chitosan) for haemostasis in massive traumatic bleeding: experience in Afghanistan. European Journal of Emergency Medicine. LWW; 2011;18(1):31–3.
• 9. Lan G, Lu B, Wang T, Wang L, Chen J, Yu K, et al. Chitosan/gelatin composite sponge is an absorbable surgical hemostatic agent. Colloids and Surfaces B: Biointerfaces. Elsevier; 2015;136:1026–34.
• 10. Lan G, Lu B, Wang T, Wang L, Chen J, Yu K, et al. Chitosan/gelatin composite sponge is an absorbable surgical hemostatic agent. Colloids and Surfaces B: Biointerfaces [Internet]. Elsevier B.V.; 2015;136:1026–34. Available from: http://dx.doi.org/10.1016/j.colsurfb.2015.10.039
• 11. Whang HS, Kirsch W, Zhu YH, Yang CZ, Hudson SM. Hemostatic agents derived from chitin and chitosan. Journal of Macromolecular Science-Polymer Reviews [Internet]. 2005;C45(4):309–23. Available from: <Go to ISI>://000233400500002
• 12. Mohd Hilmi AB, Halim AS, Jaafar H, Asiah AB, Hassan A. Chitosan dermal substitute and chitosan skin substitute contribute to accelerated full-thickness wound healing in irradiated rats. BioMed research international. Hindawi Publishing Corporation; 2013;2013.
• 13. Baxter RM, Dai T, Kimball J, Wang E, Hamblin MR, Wiesmann WP, et al. Chitosan dressing promotes healing in third degree burns in mice: Gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling. Journal of Biomedical Materials Research Part A. Wiley Online Library; 2013;101(2):340–8.
• 14. June A. Prehospital combat casualty care The starting point of battlefield survival A Prehospital Trauma Registry for Tactical Combat Casualty Care. The United States Army Medical Department Journal [Internet]. 2011;(June):103. Available from: http://www.medicalsca.com/files/amedd_journal_apr-jun_2011.pdf#page=75
• 15. Fan L, Yang J, Wu H, Hu Z, Yi J, Tong J, et al. Preparation and characterization of quaternary ammonium chitosan hydrogel with significant antibacterial activity. International journal of biological macromolecules. Elsevier; 2015;79:830–6.
• 16. Berger J, Reist M, Mayer JM, Felt O, Peppas NA, Gurny R. Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. European Journal of Pharmaceutics and Biopharmaceutics. Elsevier; 2004;57(1):19–34.
• 17. Ferreira L, Guedes JF, Almeida-Aguiar C, Fonseca AM, Neves IC. Microbial growth inhibition caused by Zn/Ag-Y zeolite materials with different amounts of silver. Colloids and surfaces B, Biointerfaces. 2016 Feb;142:141–7.