Isolated Xanthones from Lisotrigona furva Propolis in Vietnam
Öz
Propolis from stingless bees in Vietnam has
been used in traditional medicine to improve health and prevent diseases.
However, there have been few investigations on the chemical constituents and
bioactivity of Vietnamese stingless bee propolis. This work studied the
chemical composition of the stingless bee propolis collected from the nests of Lisotrigona
furva in Binhdinh province, Vietnam using combined chromatographic methods.
The chemical structures of isolated compounds were determined by MS, NMR
spectral analysis. Several xanthones including cochichinone A, cochichinone I,
cochichinone J, cratoxylumxanthone B, α-mangostanin and pruniflorone S were
isolated from the ethyl acetate extract of Lisotrigona furva propolis.
This is the first report on the chemical constituents of propolis from Lisotrigona
species. Cratoxylum cochinchinense (Hypericaceae) is the plant source
for the stingless bee Lisotrigona furva propolis.
Acknowledgements: This research is funded by Vietnam Academy of Science and Technology under grant number VAST.HTQT.BULGARIA.02/17-18
Anahtar Kelimeler
Kaynakça
- 1. Sanpa S., Popova M., Bankova V., Tunkasiri T., Eitssayeam S., Chantawannakul P. (2015). Antibacterial compounds from propolis of Tetragonula laeviceps and Tetrigona melanoleuca (Hymenoptera: Apidae) from Thailand. PLoS One, 10(5), e0126886.
- 2. Boonnak N., Karalai C., Chantrapromma S., Ponglimanont C., Fun H. K., Kanjana-Opas A., Chantrapromma K., Kato S. (2009). Anti-Pseudomonas aeruginosa xanthones from the resin and green fruits of Cratoxylum cochinchinense. Tetrahedron, 65(15), 3003-3013.
- 3. Li Z., Song Y. H., Uddin Z., Wang Y., Park K. H. (2018). Inhibition of protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase by xanthones from Cratoxylum cochinchinense, and their kinetic characterization. Bioorganic & medicinal chemistry, 26, 737-746