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Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species

Yıl 2018, Cilt: 1 Sayı: 3 - 2nd Propolis Conference Special Issue, 40 - 40, 08.12.2018

Öz

The clinical relevance of biofilms has become more apparent, however despite
this increased prominence they remain difficult to treat. Biofilm formation
relies on bacterial communication mechanisms known as quorum sensing (QS). QS
presents a novel target for antimicrobials. It is postulated that QS inhibition
would not so readily lead to the development of resistance, a common barrier in
the treatment of infectious disease. This study set out to establish whether
propolis could have an impact on biofilm formation.



Gram positive and negative bacterial species of clinical relevance were
tested, namely
Staphylococcus aureus, Escherichia coli and Pseudomonas
aeruginosa.
In addition, Chromobacterium violaceum was used to
determine QS inhibition. The effects of an ethanoic extraction of propolis
(0-2.5% v/v) on biofilm formation was assessed using colourimetry.
  Manuka honey was tested as a comparison due
to its known impact on biofilm formation and QS.

Propolis extract at low concentrations was found to
inhibit biofilm formation in all bacteria tested. Effects were similar in both
Gram positive and negative bacteria. Whilst Manuka honey also achieved an
inhibitory effect on biofilm formation, this was to a lesser extent. Propolis
was also found to be particularly potent at inhibiting QS in
C. violaceum. Our
data demonstrates that propolis has potent anti-biofilm properties. These
properties are at least in part due to QS inhibition, which is shown by the inhibition
production of homoserine lactone in
C. violaceum. This study
demonstrates the therapeutic potential of propolis in inhibiting biofilm
formation in a range of clinically relevant bacteria. 


Kaynakça

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Yıl 2018, Cilt: 1 Sayı: 3 - 2nd Propolis Conference Special Issue, 40 - 40, 08.12.2018

Öz

Kaynakça

  • .
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm 2nd Propolis Conference Special Issue
Yazarlar

K. Tennıck Bu kişi benim

S. Wafa Bu kişi benim

H. Fearnley Bu kişi benim

M. Gomez Escalada Bu kişi benim

Yayımlanma Tarihi 8 Aralık 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 1 Sayı: 3 - 2nd Propolis Conference Special Issue

Kaynak Göster

APA Tennıck, K., Wafa, S., Fearnley, H., Gomez Escalada, M. (2018). Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species. Journal of Apitherapy and Nature, 1(3), 40-40.
AMA Tennıck K, Wafa S, Fearnley H, Gomez Escalada M. Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species. J.Apit.Nat. Aralık 2018;1(3):40-40.
Chicago Tennıck, K., S. Wafa, H. Fearnley, ve M. Gomez Escalada. “Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species”. Journal of Apitherapy and Nature 1, sy. 3 (Aralık 2018): 40-40.
EndNote Tennıck K, Wafa S, Fearnley H, Gomez Escalada M (01 Aralık 2018) Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species. Journal of Apitherapy and Nature 1 3 40–40.
IEEE K. Tennıck, S. Wafa, H. Fearnley, ve M. Gomez Escalada, “Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species”, J.Apit.Nat., c. 1, sy. 3, ss. 40–40, 2018.
ISNAD Tennıck, K. vd. “Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species”. Journal of Apitherapy and Nature 1/3 (Aralık 2018), 40-40.
JAMA Tennıck K, Wafa S, Fearnley H, Gomez Escalada M. Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species. J.Apit.Nat. 2018;1:40–40.
MLA Tennıck, K. vd. “Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species”. Journal of Apitherapy and Nature, c. 1, sy. 3, 2018, ss. 40-40.
Vancouver Tennıck K, Wafa S, Fearnley H, Gomez Escalada M. Effects of Propolis on the Quorum Sensing of Selected Biofilm Producing Bacterial Species. J.Apit.Nat. 2018;1(3):40-.
  • 23484   ASOS Index