Incidence of pterygium in patients admitted to a university hospital

Abstract

Objectives: This study aimed to investigate the incidence of pterygium in a particular district of Istanbul, its association with age, and gender, and the severity of the disease. Methods: All patients aged ≥ 30 years referred to our outpatient clinics between January 2009 and December 2009 were included in this retrospective study. Age, gender, anterior segment photos, and findings of biomicroscopic eye examination were evaluated. Results: The incidence of pterygium for all age groups was 2.91% (male 1.75%, female 3.67%) with an increasing incidence with age. A significant difference was detected in its incidence favoring female patients in 40-49, and 70-79, and male patients in ≥ 80 age groups, respectively. In addition, pterygium was seen in one (75.4%) or both eyes (24.6%) preferring right or left eye in 50.7%, and 49.3% of the patients, respectively. Pterygium was in nasal or temporal region in 98%, and 2% of the patients, respectively. The disease state in 59.9% of the patients was consistent with Stage 2 pterygium. The distance of pterygium from limbus was observed greatest in 60-69, and at a minimum in 40-49 age groups. No relationship was found between eye colour and development of pterygium. Conclusion: The incidence of pterygium increases with age. Incidence of pterygium differs between genders but without any significant difference. Its occurrence in one or both eyes and in right and left eyes was not influenced by gender of the patients. A statistically significant impact of eye colour of the patient on the development of pterygium was not disclosed. J Clin Exp Invest 2013; 4 (4): 436-442

Keywords

• Pterygium, incidence, İstanbul

Bir üniversite hastanesine başvuran hastalarda pterjiyum sıklığı

Öz

Amaç: Bu çalışma, İstanbul ilinde belirli bir bölgedeki pterjiyum insidansını, yaş, cinsiyet ve hastalık şiddetini araştırmayı amaçladı. Yöntemler: Bu retrospektif çalışmada, polikliniğimize Ocak 2009 ve Aralık 2009 tarihleri arasında başvuran 30 yaş ve üzerindeki tüm hastalar dâhil edildi. Hastaların yaş, cinsiyet, ön segment fotoğrafları, biomikroskopik göz muayenesi bulguları değerlendirildi. Bulgular: Pterjiyumun tüm yaş grupları için prevelansının %2,91 (erkeklerde %1,75, kadınlarda %3,67) olduğu; yaş arttıkça pterjiyum görülme sıklığının arttığı, 40-49 yaş grubunda ve 70-79 yaş grubunda bayanlar lehine, 80 ve üstü yaş grubunda ise erkekler lehine anlamlı bir prevelans farkı mevcut olduğu ortaya konuldu. Ayrıca, pterjiyum %75,4 hastada tek tarafta, %24,6 hastada ise çift tarafta; %50,7 hastada sağ gözde, %49,3 hastada sol gözde görüldü. Pterjiyum, hastaların %98\'inde nazal bölgede iken %2\'sinde temporal bölgede idi. Hastaların %59,9\' u Evre 2 pterjiyum ile uyumlu idi. Hastanın göz rengi ile pterjiyum gelişmesi arasında bir ilişki yoktu. Sonuç: Pterjiyum gelişme riski yaş ilerledikçe yükselmektedir. Pterjiyum prevelansı cinsiyet açısından farklılık gösterse de, bu fark anlamlı düzeyde değildir. Pterjiyumun tek ya da çift gözde görülme ile sağ ya da sol gözde görülmenin cinsiyetten etkilenmediği ortaya konulmuştur. Hastanın göz renginin pterjiyum gelişimi üzerine anlamlı bir etkisinin olmadığı izlendi.

Anahtar Kelimeler

• Pterjiyum, insidans, İstanbul

Kaynakça

1. Grimmett MR, Holland EJ. Management of pterygium. In: Krachmer JH, Mannis MJ, Holland EJ, eds. Cor- nea, Surgery of Cornea and conjunctiva. Mosby St. Louis Vol III, 1997;153:1873-1875.
2. Verlee DL. Ophthalmic survey in the Solomon Islands. Am J Ophthalmol 1968;66:304-319.
3. Saw SM, Tan D. Pterygium: prevalance, demography and risk factors. Ophthalmic Epidemiol 1999;6:219- 228.
4. Rojas Jr, Malaga H. Pterygium in Lima, Peru. Ann Oph- thalmol 1986;18:147-149.
5. Forsius H, Maertens K, Fellman J. Changes of the eye caused by the climate in Rwanda, Africa. Ophthalmic Epidemiol 1995;2:107-113.
6. Detels R, Dhir SP. Ptergium: A geophraphical study. Arch Ophthalmol 1967;78:485-491.
7. Moran DJ, Hollows FC. Ptergium and ultraviolet radiation: a positive corelation. Br J Ophthalmol 1984;68:343-346.
8. Mackenzie FD, Hirsh LW, Battistutta D, Gren A. Risk anlaysis in the development of ptergia. Ophthalmol- ogy 1992;99:1056-1061.

9. Taylor HR. Studies on tear film in climatic droplet kera- topathy and ptergium. Arch Ophthalmol 1980;98:86- 88.
10. Waller SG, Adamis AP. Ptergium. In: Tasman W, Jae- ger EA, eds. Duane’s Clinical Ophthalomology. Lip- pincott Comp. Philedelphia. 1994,Chapter 35, 1-13.
11. Bilek B, Keklikçi U, Şakalar YB, et al. Comparison of Amniotic Membrane Grafts and Intraoperative Mito- mycin C for Primary Pterygium Excision. Dicle Med J 2008;35: 44-49.
12. Lim R, Mitchell P, Cumming RG. Cataract associa- tions with pinguecula and pterygium: the Blue Moun- tains Eye Study. Am J Ophthalmol 1998;126:717-719.
13. Wong TY, Foster PJ, Johnson GJ, et al. The preva- lence and risk factors for pterygium in an adult Chi- nese population in Singapore: the Tanjong Pagar sur- vey. Am J Ophthalmol 2001;131:176-183.
14. Hilgers JHC. Pterygium: its insidence, heredity and etiology. Am J Ophthalmol 1960;50:635-644.
15. Buratto L, Phillips RL, Carito G. Pterygium Surgery, Thorofare: Slack Incorporated, 2000.
16. Duke-Helder S. Pterygium. In: Duke-Helder. Diseases of the outer eye. Conjunctiva. In: System of ophthal- mology, vol 8; pt.1, St. Louis, C.V Mosby, 1965:573- 585.
17. Gazzard G, Saw SM, Farook M, et al. Pterygium in Indonesia: prevalence, severity and risk factors. Br J Ophthalmol 2002;86:1341-1346.
18. Bueno-Gimeno I, Montes-Mico R, Espana-Gregori E, Pons AM. Epidemiologic study of pterygium in a Sa- haran population. Ann Ophthalmol 2002;34:43-46.
19. McCarty C, Fu CL, Taylor HR. Epidemiology of pterygium in Victoria, Australia. Br J Ophthalmol 2000;84:289-292.
20. Luthra R, Nemesure BB, Wu SY, et al. Frequency and risk factors for pterygium in the Barbados Eye Study. Arch Ophthalmol 2001; 119:1827-1832.
21. Wu K, He M, Xu J, Li S. Pterygium in aged popu- lation in Doumen County, China. Yan Ke Xue Bao 2002;18:181-184.
22. Lu P, Chen X, Kang Y, et al. Pterygium in Tibetans: a population-based study in China. Clin Experiment Ophthalmol 2007;35:828-833.
23. Taylor HR. Aetiology of climatic droplet keratopathy and pterygium. Br J Ophthalmol 1980; 64:154-163.
24. Taylor HR, West S, Munoz B, et al. The long-term effects of visible light on the eye. Arch Ophthalmol 1992;110:99-104.
25. Hill JC, Maske R. Pathogenesis of pterygium. Eye 1989;3:218-226.
26. Liang QF, Xu L, Jin XY, et al. Epidemiology of pte- rygium in aged rural population of Beijing, China. Chin Med J (Engl) 2010;123:1699-1701.
27. Schellini SA, dos Reis Veloso CE, Lopes W, et al. Characteristics of patients with pterygium in the Botu- catu region. Arq Bras Oftalmol 2005;68:291-294.