The relationship between blood lactate levels and mortality in pediatric intensive care patients

Abstract

Objective: To determine relationship between blood lactate level and mortality rate in children admitted to the intensive care unit. Methods: 298 critically ill patients aged between 28 days and 16 years admitted to Dicle University Hospital, the third step Pediatric Intensive Care Unit in between January 2007 and December 2007 were included. Age, sex, diagnosis, Glasgow coma score points, the first measured blood lactate levels (lactate 1) and the arithmetic average of all measured blood lactate levels during treatment (lactate 2) of cases were evaluated. Patients were divided into group A (lactate < 20 mg/dl) and B (lactate &ge; 20 mg/dl). According to the results, patients were classified as survivors and non-survivors. Both lactate 1 and lactate 2 were compared with mortality rates. Results: In this study, a total of 298 patients were evaluated, 158 of them were nonsurvivors and 140 were survivors. A significant correlation was found between lactate levels and mortality rates. Lactate levels were higher in non-survivor cases (p

Keywords

• Pediatric intensive care unit, critically ill children, blood lactate levels, mortality

Çocuk yoğun bakım hastalarında kan laktat düzeyleri ile mortalite arasındaki ilişki

Öz

Amaç: Çocuk yoğun bakım servisinde takip edilen kritik hasta çocuklardaki kan laktat düzeyi ile mortalite arasındaki ilişkiyi belirlemek Yöntemler: Ocak 2007 ve Aralık 2007 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi, üçüncü basamak Çocuk Yoğun Bakım Ünitesinde takip edilmiş, kritik hasta 28 günden büyük ve 16 yaşından küçük çocuklar seçildi. Hastaların yaşı, cinsiyeti, tanısı, Glasgow koma skorlaması puanı, ilk ölçülmüş kan laktat düzeyi (laktat 1) ve tedavi sırasında tüm ölçülmüş kan laktat düzeylerinin aritmetik ortalaması (laktat 2) verileri retrospektif olarak değerlendirildi. Hastalar; grup A (laktat &le;19 mg/dl) ve grup B (laktat &ge;20mg/dl) olarak iki gruba ayrıldı. Sonlanıma göre, hastalar yaşayanlar ve ölenler olarak iki gruba ayırıldı. Bu grupların mortalite oranları ve laktat düzeylerini karşılaştırıldı. Bulgular: Çalışmada; 140&#39;ı yaşamış ve 158&#39;i ölmüş olan toplam 298 vaka değerlendirildi. Laktat 1 ve laktat 2 seviyeleri ile mortalite arasında anlamlı bir ilişki bulundu. Ölen hastalarda laktat düzeyi anlamlı olarak daha yüksekti (p

Anahtar Kelimeler

• Çocuk yoğun bakım ünitesi, kritik hasta çocuk, kan laktat düzeyi, mortalite

Kaynakça

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