Frequency of HBsAg, anti-HCV, and anti-HIV in pregnant women and/or patients with gynecologic diseases in a tertiary hospital

Abstract

Objective: Hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are viruses that can be transmitted to the health care work­ers by infected body fluids and from mother to the baby before, during or after delivery. In the present study, we aimed to investigate the frequency of hepatitis B surface antigens (HBsAg), hepatitis C antibodies (anti-HCV), and HIV antibodies (anti-HIV) in pregnant women and/or pa­tients with gynecologic diseases that admit to a university hospital in Bolu. Methods: HBsAg, anti-HCV, and anti-HIV results of the pregnant women and/or patients with gynecologic diseas­es that admitted to the obstetrics and gynecology clinics between January 2006 and June 2012 were retrospec­tively investigated. All markers were tested in the micro­biology laboratory of our hospital by using macro ELISA method (Axsyme and Architect i2000SR systems, Abbott Diagnostics, Chicago, IL, USA). Results: The frequency of HBsAg, anti-HCV, and anti- HIV positivity were 1.8%, 0.5%, and 0% in pregnant wom­en and 1.9%, 1.1%, and 0% in patients with gynecologic diseases, respectively. Conclusion: The frequencies detected in our hospital are at low levels as seen in developed countries. Since there is no effective method of prevention especially from HCV, awareness of this serologic result before high risk proce­dures will enable the doctors and the health care workers to take extensive measures to prevent the transmission of the disease. J Clin Exp Invest 2013; 4 (2): 166-170

Keywords

• anti-HCV, anti-HIV, HBsAg, pregnant wom­en, gynecology

Üçüncü basamak bir hastanedeki gebe ve/veya jinekolojik hastalıklı kadınlarda HBsAg, anti-HCV ve anti-HIV sıklığı

Öz

Amaç: Hepatit B virüsü (HBV), Hepatit C virüsü (HCV) ve insan immün yetmezlik virüsü (HIV) enfekte vücut sı­vılarıyla sağlık çalışanlarına ve enfekte anneden bebe­ğe bulaşabilen virüslerdir. Çalışmamızda Bolu ilinde bir üniversite hastanesine başvuran gebe ve/veya jinekolojik hastalıklı kadınlarda; hepatit B yüzey antijenleri (HBsAg), hepatit C antikorları (anti-HCV) ve HIV antikorlarının (an­ti-HIV) sıklığını belirlemeyi amaçladık. Yöntemler: Ocak 2006-Haziran 2012 tarihleri arasında Kadın Hastalıkları ve Doğum polikliniklerine başvuran gebe ve/veya jinekolojik hastalıklı kadınlara ait HBsAg, anti-HCV ve anti-HIV sonuçları retrospektif olarak tarandı. Tüm belirteçler hastanemiz mikrobiyoloji laboratuvarında makro ELISA yöntemi kullanılarak (Axsyme ve Archite­ct i2000SR sistemleri, Abbott Diagnostics, Chicago, IL, ABD) çalışıldı. Bulgular: HBsAg, anti-HCV ve anti-HIV pozitifliği gebe kadınlarda %1.8, %0.5 ve %0, jinekolojik hastalıklı kadın­larda ise bu oranlar %1.9, %1.1 ve %0 olarak saptandı. Sonuç: Hastanemizde tespit edilen sıklıklar gelişmiş ülkeler seviyesindedir. Özellikle HCV için sekonder ko­runma amacıyla uygulanabilecek etkin bir yöntem olma­dığından, hastalarda müdahale öncesi HBsAg, anti-HCV ve anti-HIV pozitifliğinin bilinmesi hekim ve diğer sağlık çalışanları tarafından hastalık bulaşını önleyici tedbirlerin alınmasına imkân sağlayacaktır.

Anahtar Kelimeler

• anti-HCV, anti-HIV, HBsAg, gebe ka­dınlar, jinekoloji

Kaynakça

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