Meme kanserli bir hastada 18-Floro-de-oksi-Glukoz pozitron emisyon tomografisinde multiple kemik metastazları: Olgu sunumu ve literatürün gözden geçirilmesi [Multiple bone metastases detected on 2-[18F]-fluoro-2-deoxy-d-glucose PET]

Abstract

Bone scintigraphy has been widely used to assess skeletal metastasis in patients with breast cancer. 18F-FDG-PET/CT is another imaging modality that has gained previously wide use to determine metastasis based on increased glucose metabolism in malignant cells. Generally, these two modalities give similar results in evaluation of bone metastasis of breast cancer. In this breast cancer case, 99mTc-MDP bone scintigraphy showed normal findings in regards to skeletal metastasis while 18F-FDG-PET/CT, contrast-enhanced CT and MRI revealed multiple metastatic focuses.

Keywords

• 18F-fluorodeoxyglucose, bone metastasis, bone scintigraphy, positron emission tomography

Meme kanserli bir hastada 18-Floro-de-oksi-Glukoz pozitron emisyon tomografisinde multiple kemik metastazları: Olgu sunumu ve literatürün gözden geçirilmesi

Öz

Kemik sintigrafisi, meme kanserli hastaların iskelet sistemi metastazlarının değerlendirilmesinde halen yaygın olarak kullanılmaktadır. 18F-FDG-PET/BT, malign hücrelerde artmış glukoz metabolizmasının görüntülenmesi prensibine dayanarak metastazları tespit etmede son yıllarda yaygın kullanım alanı kazanmış diğer bir görüntüleme yöntemidir. Genel olarak, meme kanserinin kemik metastazlarının tespitinde bu iki yöntem benzer sonuçlar vermektedir. Meme kanserli bu olguda 99mTc-MDP kemik sintigrafisi kemik metastazı yönünden normal bulgular göstermesine karşın 18F-FDG-PET/BT, kontrastlı BT ve MR\'da iskelet sisteminde birçok odakta kemik metastazları tespit edilmiştir.

Anahtar Kelimeler

• 18F-florodeoksiglikoz, kemik metastazı, kemik sintigrafisi, pozitron emisyon tomografisi

Kaynakça

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