Investigation of Framingham Risk Factors in Turkish adults

Abstract

Objectives: The aim of this study was to determine 10-year risk for development of cardiovascular diseases using Framingham risk scoring as a tool for the estimation of coronary risk and renew the blood lipid levels. Materials and methods: Samples from fasting 3169 healthy donors declaring as having no cardiovascular disease and diabetes (1800 women, mean age 46.8±9.2 years) and 1369 men, mean age 46.03±8.4 years) were tested and scored according to risk factors in both genders. Results: When average values were considered, total cholesterol level was higher (204±42 mg/dL) according to reactive insert reference values. High total kolesterol and low HDL-C levels were seen in 20% and 19.5% of men and 32.6% and 1.1% of women, respectively. The number of participants having systolic blood pressure ≥130 mmHg and diastolic blood pressure ≥ 85 mmHg were 775 (24.5%) and the distribution of those values was 10.6 % in men and 13.9% in women. The mean 10-year cardiovascular disease risks were 9.4 % in men and 4.6% in women among 3169 participants. Conclusion: A 10-year risk of coronary disease, in Turkish males was 2-fold higher than in Turkish females. Use of Framingham study in clinical assessments maintains to be a valid method in preventive approaches for development of cardiovascular diseases.

Keywords

• Framingham risk score, coronary heart disease, HDL-cholesterol, LDL-cholesterol, total cholesterol

Türk erişkinlerde Framingham Risk Faktörlerinin araştırılması

Öz

Amaç: Çalışmanın amacı, Framingham Risk Skorlamasını kullanarak belli bir grupta 10 yıllık koroner kalp hastalığı gelişim riskini belirlemek ve kan lipid değerlerini tekrar gözden geçirmektir. Gereç ve yöntemler: Örnekler kardiyovasküler bir hastalığı ve diyabeti olmadığını beyan eden 3169 katılımcıdan toplandıktan sonra (1800 kadın; yaş ortalaması 46.8±9.2 yıl ve 1369 erkek; yaş ortalaması 46.03±8.4 yıl) bir dizi risk faktörleri [yaş, total kolesterol (kolesterol-T), cinsiyet, HDL-kolesterol (HDL-K), sistolik kan basıncı, diyabet varlığı ve sigara kullanımı] yönünden skorlandırılmıştır. Bulgular: Ortalama değerler göz önüne alındığında, kolesterol-T düzeyi, reaktif içeriğinde belirlenen üst sınırın (200 mg/dL) üzerinde tespit edilmiştir (204±42 mg/dL). Yüksek kolesterol-T ve düşük HDL-K düzeyi, erkeklerde sırasıyla % 20 ve % 19.5 ve kadınlarda % 32.6 ve % 1.1 olarak bulundu. Sistolik kan basıncı ≥130 mmHg ve diyastolik kan basıncı ≥85 mmHg olan katılımcıların sayısı 775 (% 24.5) adet olup bu değerlerin cinsiyete göre dağılımı erkeklerde % 10.6, kadınlarda % 13.9 olarak bulunmuştur. On yıllık koroner kalp hastalığı riski, 3169 katılımcı arasından erkeklerde % 9.4 ve kadınlarda % 4.6 bulunmuştur (p

Anahtar Kelimeler

• Framingham risk skorlaması, koroner kalp hastalığı, HDL-kolesterol, LDL-kolesterol, total kolesterol

Kaynakça

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