BibTex RIS Kaynak Göster

A case of hyperamylasemia: Macroamylasemia? Review of the literature

Yıl 2011, , 98 - 101, 01.03.2011
https://doi.org/10.5799/ahinjs.01.2011.01.0219

Öz

Amylase is one of the analyzed tests in patients evaluated for abdominal pain. Macroenzyme disorder, a benign condition without any requirement for any treatment is among the reasons of the high serum enzyme levels. Macroamylasemia is the most frequently encountered macroenzyme disorder. Herein, we present a patient with abdominal pain and persistent high amylase levels considered as macroamylasemia. Establishing the diagnosis of macroenzyme disorder as the cause of the unexplained high enzyme levels prevents unnecessary, expensive and even invasive diagnostic and therapeutic procedures.

Kaynakça

  • Pieper-Bigelow C, Strocchi A, Levitt MD. Where does se- rum amylase come from and where does it go? Gastroen- terol Clin North Am 1990;19:793-810.
  • Clink D, Weaver D, Bouwman D, Sessions S, Stephany J. Clinical application of organ spesific isoamylases. Am Surg 1982;48:422-425.
  • Türkçapar N, Özden A. Macroenzymes. Güncel Gastroen- teroloji 2005;9:161-166.
  • Goldberg DM, Spooner RJ. Amylase, isoamylase and ma- croamylase. Digestion 1975;13:56-75.
  • Galasso PJ, Litin SC, O’Brien JF. The macroenzymes: a clinical review. Mayo Clin Proc 1993;68:349-354.
  • Srivastava R, Fraser C, Gentleman D, Jamieson La, Murphy MJ. Hyperamylasemia: not the usual aspects. BMJ 2005;331:890-891.
  • Otsuki M. Usefulness of amylase isoenzyme determination for the diagnosis of pancreatic diseases. Nippon Rinsho 1995;53:1184-1191.
  • Warshaw AL, Hawboldt MM. Puzzling persistent hypera- mylasemia, probably neither pancreatic nor pathologic. Am J Surg 1988;155:453-456.
  • Gallucci F, Buono R, Ferrara L, Madrid E, Miraglia S, Uomo G. Chronic asymptomatic hyperamylasemia unre- lated to pancreatic diseases. Adv Med Sci 2010;30:143- 145.
  • Levitt MD, Cooperband SR. Hyperamylasemi from the binding of serum amylase by an 11S IgA globulin. N Eng J Med 1968;278:474-479.
  • Klonoff DC. Macroamylasemi and other immunoglobulin- complexed enzyme disorders. West J Med 1980;133:392- 407.
  • Durr HK, Bode C, Krupinski R, Bode CH. A comparison between naturally occuring macroamylasemia and macroamylasemia induced by hydroxyethyl-starch. Eur J Clin Invest 1978;8:189-191.
  • Levitt MD. Clinical use of amylase clearence and isoamy- lase measurements. Mayo Clin Proc 1979;54:428-431.
  • Levitt MD, Ellis C. A rapid and simple assay to determine if macroamylase is the cause of hyperamylasemia. Gastro- enterology 1982;83:378-382.

Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi

Yıl 2011, , 98 - 101, 01.03.2011
https://doi.org/10.5799/ahinjs.01.2011.01.0219

Öz

Karın ağrısı ile başvuran hastalarda istenen tetkiklerden biri de serum amilazıdır. Serum amilaz enzim yükseklik nedenlerinden birisi de selim seyirli ve herhangi bir tedavi gerektirmeyen makroenzimlerdir. Makroenzimlerin en sık görüleni makroamilazemidir. Yazımızda karın ağrısı ve sebat eden amilaz yüksekliği ile başvuran makroamilazemili bir vaka sunulmaktadır. Açıklanamayan enzim artışının nedeni olarak makroenzimin tespit edilememesi pahalı, gereksiz, sıklıkla invaziv işlemlerle alternatif tanıların araştırılmasına ve cerrahi gibi agresif tedavilere neden olabilir.

Kaynakça

  • Pieper-Bigelow C, Strocchi A, Levitt MD. Where does se- rum amylase come from and where does it go? Gastroen- terol Clin North Am 1990;19:793-810.
  • Clink D, Weaver D, Bouwman D, Sessions S, Stephany J. Clinical application of organ spesific isoamylases. Am Surg 1982;48:422-425.
  • Türkçapar N, Özden A. Macroenzymes. Güncel Gastroen- teroloji 2005;9:161-166.
  • Goldberg DM, Spooner RJ. Amylase, isoamylase and ma- croamylase. Digestion 1975;13:56-75.
  • Galasso PJ, Litin SC, O’Brien JF. The macroenzymes: a clinical review. Mayo Clin Proc 1993;68:349-354.
  • Srivastava R, Fraser C, Gentleman D, Jamieson La, Murphy MJ. Hyperamylasemia: not the usual aspects. BMJ 2005;331:890-891.
  • Otsuki M. Usefulness of amylase isoenzyme determination for the diagnosis of pancreatic diseases. Nippon Rinsho 1995;53:1184-1191.
  • Warshaw AL, Hawboldt MM. Puzzling persistent hypera- mylasemia, probably neither pancreatic nor pathologic. Am J Surg 1988;155:453-456.
  • Gallucci F, Buono R, Ferrara L, Madrid E, Miraglia S, Uomo G. Chronic asymptomatic hyperamylasemia unre- lated to pancreatic diseases. Adv Med Sci 2010;30:143- 145.
  • Levitt MD, Cooperband SR. Hyperamylasemi from the binding of serum amylase by an 11S IgA globulin. N Eng J Med 1968;278:474-479.
  • Klonoff DC. Macroamylasemi and other immunoglobulin- complexed enzyme disorders. West J Med 1980;133:392- 407.
  • Durr HK, Bode C, Krupinski R, Bode CH. A comparison between naturally occuring macroamylasemia and macroamylasemia induced by hydroxyethyl-starch. Eur J Clin Invest 1978;8:189-191.
  • Levitt MD. Clinical use of amylase clearence and isoamy- lase measurements. Mayo Clin Proc 1979;54:428-431.
  • Levitt MD, Ellis C. A rapid and simple assay to determine if macroamylase is the cause of hyperamylasemia. Gastro- enterology 1982;83:378-382.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Olgu Sunumu
Yazarlar

Mehmet Yalnız Bu kişi benim

Mehmet Asoğlu Bu kişi benim

Ulvi Demirel Bu kişi benim

Cem Aygün Bu kişi benim

İbrahim Halil Bahçecioğlu Bu kişi benim

Yayımlanma Tarihi 1 Mart 2011
Yayımlandığı Sayı Yıl 2011

Kaynak Göster

APA Yalnız, M., Asoğlu, M., Demirel, U., Aygün, C., vd. (2011). Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi. Journal of Clinical and Experimental Investigations, 2(1), 98-101. https://doi.org/10.5799/ahinjs.01.2011.01.0219
AMA Yalnız M, Asoğlu M, Demirel U, Aygün C, Bahçecioğlu İH. Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi. J Clin Exp Invest. Mart 2011;2(1):98-101. doi:10.5799/ahinjs.01.2011.01.0219
Chicago Yalnız, Mehmet, Mehmet Asoğlu, Ulvi Demirel, Cem Aygün, ve İbrahim Halil Bahçecioğlu. “Hiperamilazemili Bir Vaka: Makroamilazemi? Literatürün gözden geçirilmesi”. Journal of Clinical and Experimental Investigations 2, sy. 1 (Mart 2011): 98-101. https://doi.org/10.5799/ahinjs.01.2011.01.0219.
EndNote Yalnız M, Asoğlu M, Demirel U, Aygün C, Bahçecioğlu İH (01 Mart 2011) Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi. Journal of Clinical and Experimental Investigations 2 1 98–101.
IEEE M. Yalnız, M. Asoğlu, U. Demirel, C. Aygün, ve İ. H. Bahçecioğlu, “Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi”, J Clin Exp Invest, c. 2, sy. 1, ss. 98–101, 2011, doi: 10.5799/ahinjs.01.2011.01.0219.
ISNAD Yalnız, Mehmet vd. “Hiperamilazemili Bir Vaka: Makroamilazemi? Literatürün gözden geçirilmesi”. Journal of Clinical and Experimental Investigations 2/1 (Mart 2011), 98-101. https://doi.org/10.5799/ahinjs.01.2011.01.0219.
JAMA Yalnız M, Asoğlu M, Demirel U, Aygün C, Bahçecioğlu İH. Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi. J Clin Exp Invest. 2011;2:98–101.
MLA Yalnız, Mehmet vd. “Hiperamilazemili Bir Vaka: Makroamilazemi? Literatürün gözden geçirilmesi”. Journal of Clinical and Experimental Investigations, c. 2, sy. 1, 2011, ss. 98-101, doi:10.5799/ahinjs.01.2011.01.0219.
Vancouver Yalnız M, Asoğlu M, Demirel U, Aygün C, Bahçecioğlu İH. Hiperamilazemili bir vaka: Makroamilazemi? Literatürün gözden geçirilmesi. J Clin Exp Invest. 2011;2(1):98-101.