Beta-human chorionic gonadotropin concentrations in cervicovaginal secretions as an early marker of preterm delivery

Abstract

Objectives: To investigate beta-human corionic gonadotropin (β-hCG) levels in cervicovaginal secretions as an early marker for preterm delivery. Methods: The study included 55 patients at 25-36 of gestational weeks with preterm delivery risk factors including a history of preterm labor in a previous pregnancy or history of second trimester abortion. Beta-human chorionic gonadotropin (β-hCG) levels of cervicovaginal secretions were measured in all patients by the radioimmunoassay method using a commercial kit. Results: Preterm delivery was observed in 25 patients and 30 patients gave term delivery. No significant differences were found between preterm and term delivery groups in age, gravidity and parity (P>0.05). APGAR scores and anthropometric measurements of newborns were significantly lower in preterm delivery group (P

Keywords

• Preterm delivery, beta-hCG, predictive value, servico-vaginal secretions

Preterm doğumun erken bir belirteci olarak serviko-vajinal sekresyonlardaki gonadotropin konsantrasyonları

Öz

Amaç: Preterm doğum erken belirteci olarak serviko-vajinal sekresyonlardaki koriyonik gonadotropin\'in rolünü araştırmak. Yöntemler: Bir önceki doğumu erken doğum veya ikinci trimester düşük öyküsü risk faktörü olan, 25-36 gebelik haftasına sahip 55 gebe çalışmaya alındı. Hastaların tümünde servikovajinal sekresyonlardaki beta-insan koriyonik gonadotropin (β-hCG) düzeyleri radioimmunassay yöntemiyle ticari bir kit kullanılarak ölçüldü. Bulgular: Gebelerden 25\'i preterm, 30\'u term doğum yaptı. Term ve preterm doğum yapana gebe grupları arasında yaş, gebelik sayısı ve parite açısından farklılık saptanmadı (P>0.05). Preterm doğum grubunda yenidoğan APGAR skorları ve bebeklerin antropometrik ölçümleri term doğum grubundan anlamlı düşük bulundu (P

Anahtar Kelimeler

• Preterm doğum, beta-hCG, prediktif değer, serviko-vajinal sekresyonlar

Kaynakça

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