The pathogenesis of atopic dermatitis

Öz

Atopic dermatitis (AD) is a very common and recurrent chronic an inflammatory skin diseases. Atopic dermatitis is a health problem for especially industrialized countries. However in recent years AD has been more common in our country. Multiple factors play role in the pathogenesis of AD. Although the etiology is not clear, it may be related to immunologically deviated T cell functions with precipitating factors in genetically predisposed people. In present article, we reviewed actual literature on the etiopathogenesis of AD.

Anahtar Kelimeler

• Atopic dermatitis, pathogenesis, genetic, immunological mechanisms

Atopik dermatit patogenezi

Öz

Atopik dermatit (AD), klinikte sık karşılaşılan ve tekrarlayan kronik inflamatuvar bir cilt hastalığıdır. AD özellikle endüstriyelleşmiş ülkelerin sorunudur. Ancak son yıllarda ülkemizde de AD sıklığı artmaktadır. Atopik dermatit\'in patogenezinde birçok faktörün üzerinde durulmaktadır. Ancak etyolojisi tam olarak bilinmemekle beraber genetik olarak eğilimli kişilerde bir grup tetikleyici faktörlerin etkisiyle T hücre fonksiyonlarındaki immünoljik sapma sonucu oluşmaktadır. Bu makalede atopik dermatitin etyopatogenezi ile ilgili güncel literatür bilgiler gözden geçirilmiştir.

Anahtar Kelimeler

• Atopik dermatit, patogenez, genetik, immünolojik

Kaynakça

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