The efficiency and side-effects of low-dose Fludarabine-Cyclophosphamide in the treatment of chronic lymphocytic leukemia

Öz

Anahtar Kelimeler

• Kronik lenfositik lösemi, fludarabin-siklofosfamid tedavisi, hematolojik toksisite

The efficiency and side-effects of low-dose Fludarabine-Cyclophosphamide in the treatment of chronic lymphocytic leukemia

Öz

The aim of this study was to evaluate the efficiency, as well as the hematologic and non-he

Anahtar Kelimeler

• -

Kaynakça

1. Laurenti L, Tarnani M, De Padua L, et al. Oral fludarabine and cyclophosphamide as front-line chemotherapy in pa- tients with chronic lymphocytic leukemia. The impact of biological parameters in the response duration. Ann Hema- tol 2008;87:891-8.
2. Catovsky D, Richards S, Matutes E, et al. Assessment of flu- darabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. Lancet 2007;370:197-8.
3. Lin TS. What is the optimal initial treatment for chron- ic lymphocytic leukemia? Oncology (Williston Park) 2007;21:1641-9
4. Foon KA, Boyiadzis M, Land SR, et al. Chemoimmunother- apy with low-dose fludarabine and cyclophosphamide and high dose rituximab in previously untreated patients with chronic lymphocytic leukemia. J Clin Oncol 2009;27:479- 80.
5. Forconi F, Fabbri A, Lenoci M, et al. Low-dose oral flu- darabine plus cyclophosphamide in elderly patients with untreated and relapsed or refractory chronic lymphocytic Leukaemia. Hematol Oncol 2008;26:247-51.
6. Fabbri A, Lenoci M, Gozzetti A, et al. Low-dose oral flu- darabine plus cyclophosphamide as first-line treatment in elderly patients with indolent non-Hodgkin lymphoma. Br J Haematol 2007;139:90-3.
7. Cazin B, Divine M, Leprêtre S, et al. High efficacy with five days schedule of oral fludarabine phosphate and cyclo- phosphamide in patients with previously untreated chronic lymphocytic leukaemia. Br J Haematol 2008;143:54-9. 2008;143:54-9.