Three Cases of Adenomyoepithelioma: An Unusual Breast Neoplasm

Yıl 2016, , 91 - 93, 01.03.2016

Murat Özgür Kılıç , Meral Sen Cenap Dener Dilek Kösehan , Sibel Yenidünya

https://doi.org/10.5799/jcei.328693

Öz

Adenomyoepithelioma of the breast is an unusual tumor characterized by biphasic proliferation of both epithelial and
myoepithelial cells. Although most of these tumors have a benign course, a small number of malignant lesions have
been reported in the literature. Adenomyoepithelioma is also characterized by propensity for local recurrence. Therefore,
the sufficiency of initial surgery plays very important role in the management of these tumors. Due to the potential
to malignant transformation and high risk of local recurrence, totally excision with wide margins should be performed
in surgical treatment of these tumors. In this paper, three cases of adenomyoepithelioma of the breast with different
clinical presentations and radiological findings were reported. J Clin Exp Invest 2016; 7 (1): 91-93

Anahtar Kelimeler

Adenomyoepithelioma, breast, diagnosis, treatment

Kaynakça

• 1. Hamperl H. The myothelia (myoepithelial cells). Normal state; regressive changes; hyperplasia; tumors. Curr Topics Pathol 1970;53:161-220.
• 2. Ruiz-Delgado ML, López-Ruiz JA, Eizaguirre B, et al. Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. Acta Radiol 2007;48:27-29.
• 3. Howlett DC, Mason CH, Biswas S, et al. Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology. AJR 2003;180:799-803.
• 4. Fırat U, Keleş A, Mızrak B. Yüksek Ki-67 indeksi ile birlikte memenin malign adenomiyoepitelyoması: Literatür eşliğinde olgu sunumu. J Clin Exp Invest 2011;2:425-429.
• 5. Harigopal M, Park H, Chen X, Rosen PP. Pathologic quiz case: a rapidly increasing breast mass in a postmenopausal woman. Malignant adenomyoepithelioma. Arch Pathol Lab Med 2004;128:235-236.
• 6. Park YM, Park JS, Jung HS, et al. Imaging features of benign adenomyoepithelioma of the breast. J Clin Ultrasound 2013;41:218-223.
• 7. Hatzung G, Grunwald S, Zygmunt M, et al. Sonoelastography in the diagnosis of malignant and benign breast lesions: initial clinical experiences. Ultraschall Med 2010;31:596- 603.
• 8. Petrozza V, Pasciuti G, Pacchiarotti A, et al. Breast adenomyoepithelioma: a case report with malignant proliferation of epithelial and myoepithelial elements. World J Surg Oncol 2013;11:285.
• 9. Behranwala KA, Nasiri N, A’Hern R, Gui GP. Clinical presentation and long-term outcome of pure myoepithelial carcinoma of the breast. Eur J Surg Oncol 2004;30:357-361.
• 10. Iyengar P, Ali SZ, Brogi E. Fine-needle aspiration cytology of mammary adenomyoepithelioma: a study of 12 patients. Cancer 2006;108:250-256.