Araştırma Makalesi

Autonomic Dysfunction in Epileptic Patients

Cilt: 9 Sayı: 2 13 Haziran 2018
PDF İndir
EN

Autonomic Dysfunction in Epileptic Patients

Abstract

Objective: To investigate autonomic symptoms in different types of epilepsy in comparison to
control subjects. To observe whether autonomic symptoms cause possible morbidity and
mortality and to make a preliminary remedy
Patients and Methods: A retrospective chart review was conducted for 28 patients diagnosed
with epilepsy including 18 patients with complex partial epilepsy (CPE) and 10 patients with
primary generalized epilepsy (PJE). Their autonomic symptoms were assessed using the
COMPASS-31 questionnaire in comparison to a control group of 18 subjects.
Results: No statistically significant differences were found in autonomic dysfunction symptoms
between patients with CPE and patients with PJE. However, constipation and insomnia which
autonomic symptoms were statistically significantly more common in epileptic patients
compared to the control group.
Conclusions: It is important to recognize and watch out for symptoms of autonomic dysfunction
in patients with epilepsy. We believe that awareness for these symptoms is essential both to
reduce associated disability and develop specific treatment strategies and to predict sudden
unexpected death in epileptic patients.

Keywords

Kaynakça

  1. 1. Baysal Kıraç L. Otonomik belirtili nöbeti olan olgularda elektrofizyolojik verilerin ve otoantikorların araştırılması (Yan dal uzmanlık tezi). İstanbul: İstanbul Üniversitesi İstanbul Tıp Fakültesi; 2015.
  2. 2. Moseley B, Bateman L, Millichap JJ, Wirrell E, Panayiotopoulos CP. Autonomic epileptic seizures, autonomic effects of seizures, and SUDEP. Epilepsy Behav. 2013;26:375-85.
  3. 3. Miller WR, Young N, Friedman D, Buelow JM, Devinsky O. Discussing sudden unexpected death in epilepsy (SUDEP) with patients: Practices of health-care providers. Epilepsy Behav. 2014; 32: 38-41.
  4. 4. Ramachandran Nair R, Jack SM, Strohm S. SUDEP: To discuss or not? Recommendations from bereaved relatives. Epilepsy Behav. 2016; 56: 20-5.
  5. 5. Butler IJ, Lankford JE, Hashmi SS, Numan MT. Biogenic amine metabolism in juvenile neurocardiogenic syncope with dysautonomia. Ann Clin Transl Neurol. 2014;1:251-7.
  6. 6. Wadhwania R, Butler I, Hashmi S, Numan M, Lankford J. Dysautonomia: Retrospective study of amino acids, cytokines and neurotransmitter metabolites. Ann Neurol. 2016;80:S299.
  7. 7. Gordon N. Reflex sympathetic dystrophy. Brain Dev 1996;18:257-62.6. Guidelines for epidemiologic studies on epilepsy. Commission on Epidemiology and Prognosis, International League Against Epilepsy. Epilepsia. 1993;34(4):592-6.
  8. 8. Devinsky O. Effects of seizures on autonomic and cardiovascular function. Epilepsy Curr. 2004;4:43-46.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

13 Haziran 2018

Gönderilme Tarihi

15 Ocak 2018

Kabul Tarihi

11 Mart 2018

Yayımlandığı Sayı

Yıl 2018 Cilt: 9 Sayı: 2

Kaynak Göster

APA
Özer, G. (2018). Autonomic Dysfunction in Epileptic Patients. Journal of Clinical and Experimental Investigations, 9(2), 76-80. https://doi.org/10.5799/jcei.433809
AMA
1.Özer G. Autonomic Dysfunction in Epileptic Patients. J Clin Exp Invest. 2018;9(2):76-80. doi:10.5799/jcei.433809
Chicago
Özer, Gökhan. 2018. “Autonomic Dysfunction in Epileptic Patients”. Journal of Clinical and Experimental Investigations 9 (2): 76-80. https://doi.org/10.5799/jcei.433809.
EndNote
Özer G (01 Haziran 2018) Autonomic Dysfunction in Epileptic Patients. Journal of Clinical and Experimental Investigations 9 2 76–80.
IEEE
[1]G. Özer, “Autonomic Dysfunction in Epileptic Patients”, J Clin Exp Invest, c. 9, sy 2, ss. 76–80, Haz. 2018, doi: 10.5799/jcei.433809.
ISNAD
Özer, Gökhan. “Autonomic Dysfunction in Epileptic Patients”. Journal of Clinical and Experimental Investigations 9/2 (01 Haziran 2018): 76-80. https://doi.org/10.5799/jcei.433809.
JAMA
1.Özer G. Autonomic Dysfunction in Epileptic Patients. J Clin Exp Invest. 2018;9:76–80.
MLA
Özer, Gökhan. “Autonomic Dysfunction in Epileptic Patients”. Journal of Clinical and Experimental Investigations, c. 9, sy 2, Haziran 2018, ss. 76-80, doi:10.5799/jcei.433809.
Vancouver
1.Gökhan Özer. Autonomic Dysfunction in Epileptic Patients. J Clin Exp Invest. 01 Haziran 2018;9(2):76-80. doi:10.5799/jcei.433809