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BibTex RIS Kaynak Göster

Yıl 2018, Cilt: 9 Sayı: 2, 100 - 102, 13.06.2018

Erdinç Şengüldür

https://doi.org/10.5799/jcei.433821

Öz

Kaynakça

  • 1. Evoy KE, Morrison MD, Saklad SR. Abuse and misuse of pregabalin and gabapentin. Drugs. 2017; 77: 403-26.
  • 2. Milicevic C, Crnobaric C, Nikolic S, Lecic-Tosevski D. A case of pregabalin intoxication. Psychiatriki. 2012;23:162-5.
  • 3. Ben-Menachem E. Pregabalin pharmacology and its relevance to clinical practice. Epilepsia. 2004;45:13-18.
  • 4. Aksakal E, Bakırcı E, Emet M. Complete atrioventricular block due to overdose of pregabalin. Am J Emerg Med. 2012;30:2101.
  • 5. Randinitis EJ, Posvar EL, Alvey CW, Sedman AJ, Cook JA, Bockbrader HN. Pharmacokinetics of pregabalin in subjects with various degrees of renal function. J Clin Pharmacol. 2003;43:277-83.
  • 6. De Smedt RHE, Jaarsma T, van den Broek SAJ, Haaijer-Ruskamp FM. Decompensation of chronic heart failure associatedwith pregabalin in a 73-year-old patient withpostherpetic neuralgia: a case report. Br J Clin Pharmacol. 2008;66:327-8. 7. De Smedt RHE, Jaarsma T, van den Broek SAJ, Haaijer-Ruskamp FM. Decompensation of chronic heart failure associatedwith pregabalin in a 73-year-old patient withpostherpetic neuralgia: a case report. Br J Clin Pharmacol. 2008;66:327-8.
  • 8. Belli E, Erkalp K, Yangın Z, Fadıllıoğlu S, Alagöl A. A new analgesic drug: pregabalin and the first intoxications. Agri. 2013; 25: 187-9.

Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram

Yıl 2018, Cilt: 9 Sayı: 2, 100 - 102, 13.06.2018

Erdinç Şengüldür

https://doi.org/10.5799/jcei.433821

Öz

Pregabalin is a lipophilic analogue of gamma-aminobutyric acid (GABA) and has a similar
chemical structure to gabapentin and is more potent than gabapentin. This report documents
the case of a 28-year-old male presenting with suicidal attempt by pregabalin intake. The
patient had an abnormal PR interval (reversible AV-block). He was managed with general
supportive care and symptomatic approach such as discontinuation of the drug, hydration with
IV fluids, oxygenation, gastric lavage and activated charcoal administration.

Anahtar Kelimeler

Pregabalin intoxication AV-block

Kaynakça

  • 1. Evoy KE, Morrison MD, Saklad SR. Abuse and misuse of pregabalin and gabapentin. Drugs. 2017; 77: 403-26.
  • 2. Milicevic C, Crnobaric C, Nikolic S, Lecic-Tosevski D. A case of pregabalin intoxication. Psychiatriki. 2012;23:162-5.
  • 3. Ben-Menachem E. Pregabalin pharmacology and its relevance to clinical practice. Epilepsia. 2004;45:13-18.
  • 4. Aksakal E, Bakırcı E, Emet M. Complete atrioventricular block due to overdose of pregabalin. Am J Emerg Med. 2012;30:2101.
  • 5. Randinitis EJ, Posvar EL, Alvey CW, Sedman AJ, Cook JA, Bockbrader HN. Pharmacokinetics of pregabalin in subjects with various degrees of renal function. J Clin Pharmacol. 2003;43:277-83.
  • 6. De Smedt RHE, Jaarsma T, van den Broek SAJ, Haaijer-Ruskamp FM. Decompensation of chronic heart failure associatedwith pregabalin in a 73-year-old patient withpostherpetic neuralgia: a case report. Br J Clin Pharmacol. 2008;66:327-8. 7. De Smedt RHE, Jaarsma T, van den Broek SAJ, Haaijer-Ruskamp FM. Decompensation of chronic heart failure associatedwith pregabalin in a 73-year-old patient withpostherpetic neuralgia: a case report. Br J Clin Pharmacol. 2008;66:327-8.
  • 8. Belli E, Erkalp K, Yangın Z, Fadıllıoğlu S, Alagöl A. A new analgesic drug: pregabalin and the first intoxications. Agri. 2013; 25: 187-9.
Toplam 7 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunumu
Yazarlar

Erdinç Şengüldür Bu kişi benim

Yayımlanma Tarihi 13 Haziran 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 9 Sayı: 2

Kaynak Göster

APA Şengüldür, E. (2018). Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram. Journal of Clinical and Experimental Investigations, 9(2), 100-102. https://doi.org/10.5799/jcei.433821
AMA Şengüldür E. Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram. J Clin Exp Invest. Haziran 2018;9(2):100-102. doi:10.5799/jcei.433821
Chicago Şengüldür, Erdinç. “Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram”. Journal of Clinical and Experimental Investigations 9, sy. 2 (Haziran 2018): 100-102. https://doi.org/10.5799/jcei.433821.
EndNote Şengüldür E (01 Haziran 2018) Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram. Journal of Clinical and Experimental Investigations 9 2 100–102.
IEEE E. Şengüldür, “Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram”, J Clin Exp Invest, c. 9, sy. 2, ss. 100–102, 2018, doi: 10.5799/jcei.433821.
ISNAD Şengüldür, Erdinç. “Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram”. Journal of Clinical and Experimental Investigations 9/2 (Haziran 2018), 100-102. https://doi.org/10.5799/jcei.433821.
JAMA Şengüldür E. Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram. J Clin Exp Invest. 2018;9:100–102.
MLA Şengüldür, Erdinç. “Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram”. Journal of Clinical and Experimental Investigations, c. 9, sy. 2, 2018, ss. 100-2, doi:10.5799/jcei.433821.
Vancouver Şengüldür E. Pregabalin Intoxication-Induced Prolonged PR Interval on Electrocardiogram. J Clin Exp Invest. 2018;9(2):100-2.